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Publications

Highlighted Manuscripts

Afzali B, Lechler RI, Hernandez-Fuentes MP. Allorecognition and the alloresponse: clinical implications. Tiss Antigens 69:545-56, 2007.

 [PubMed] [Reprint]
Aly TA, Ide A, Jahromi MM, Barker JM, Fernando MS, Babu SR, Yu L, Miao D, Erlich HA, Fain PR, Barriga KJ, Norris JM, Rewers MJ, and Eisenbarth GS. Extreme genetic risk for type 1A diabetes. Proc Natl Acad Sci. 103:14074-14079, 2006. [PubMed] [Reprint]
Aly TA, Eller E, Ide A, Gowan K, Babu SR, Erlich HA, Rewers MJ, Eisenbarth GS, and Fain PR. Multi-SNP analysis of MHC region: Remarkable conservation of HLA-A1-B8-DR3 haplotype. Diabetes 55:1265-1269, 2006. [PubMed] [Reprint]
Asare A, Gao Z, Carey VJ, Wang R, Seyfert-Margolis V. Power enhancement via multivariate outlier testing with gene expression arrays.  Bioinformatics 25: 48-53, 2009. [PubMed] [Reprint]
Asare AL, Kolchinsky SA, Gao Z, Wang R, Raddassi K, Bourcier K, Seyfert-Margolis V. Differential gene expression profiles are dependent upon method of peripheral blood collection and RNA isolation. BMC Genomics 9:474, 2008. [PubMed] [Reprint]
Babaya N, Liu E, Miao D, Li M, Yu L, Eisenbarth GS. Murine high specificity/sensitivity competitive europium insulin autoantibody assay. Diabetes Technol Ther 11:227-33, 2009. [PubMed] [Reprint]
Barker JM, Goehrig SH, Barriga K, Hoffman M, Slover R, Eisenbarth GS et al. Clinical characteristics of children diagnosed with type 1 diabetes through intensive screening and follow-up. Diabetes Care 27:1399-1404, 2004. [PubMed] [Reprint]
Barker JM, Barriga K, Yu L, Miao D, Erlich H, Norris JN et al. Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). JCEM 89:3896-3902, 2004. [PubMed] [Reprint]
Barker JM, Barriga K, Yu L, Miao D, Erlich H, Norris JN et al. Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). JCEM 89:3896-3902, 2004. [PubMed] [Reprint]
Baschal EE, Aly TA, Babu SR, Fernando MS, Yu L, Miao D et al. HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY population. Diabetes 56:2405-2409, 2007. [PubMed] [Reprint]
Bluestone JA, Krensky AM, Turka LA, Rotrosen D, Matthews JB. Ten years of the Immune Tolerance Network: An integrated clinical research organization.  Sci Transl Med 2, 19cm7, 2010. [PubMed] [Reprint]
Bluestone JA, Matthews JB, Krensky AM. The immune tolerance network: the "Holy Grail" comes to the clinic. J Am Soc Nephrol 11:2141-6, 2000. [PubMed] [Reprint]
Bluestone JA, Matthews J. The Immune Tolerance Network: tolerance at the crossroads. Philos Trans R Soc Lond B Biol Sci 356:773-6, 2001. [PubMed] [Reprint]
Bluestone JA, Matthews JB. The immune tolerance network--an NIH/JDF-supported initiative to bring tolerance research into the clinic: a major new resource for clinical immunologists. Clin Immunol 96:171-3, 2000. [PubMed] [Reprint]
Bourdette DN, Edmonds, E, Smith C, Bowen JD, Guttmann CRG, Nagy ZP, Simon J, Whitham R, Lovera J, Yadav V, Mass M, Spencer L, Culbertson N, Bartholomew RM, Theofan G, Milano J, Offner H, Vandenbark AA. A highly immunogenic trivalent T cell receptor peptide vaccine. Multiple Sclerosis 11: 1-10, 2005. [PubMed] [Reprint]
Brennan DC, Shannon MB, Koch MJ, Polonsky KS, Desai N, Shapiro J. Portal vein thrombosis complicating islet transplantation in a recipient with the Factor V Leiden mutation. Transplantation 78:172-3, 2004. [PubMed] [Reprint]
Bunde T, Kirchner A, Hoffmeister B, Habedank D, Hetzer R, Cherepnev G, Proesch S, Reinke P, Volk H-D, Lehmkuhl H, Kern F. Protection from cytomegalovirus after transplantation is orrelated with immediate early 1–specific CD8 T cells. J Exp Med 201: 1031–1036, 2005. [PubMed] [Reprint]
Casale TB, Busse WW, Kline JN, Ballas ZK, Moss MH, Townley RG, Mokhtarani M, Seyfert-Margolis V, Asare A, Bateman K, Deniz Y, Immune Tolerance Network. Omalizumab Pretreatment Decreases Acute Reactions Following Rush Immunotherapy for Ragweed-Induced Seasonal Allergic Rhinitis. J Allergy Clin Immunol 117: 134-140, 2006. [PubMed] [Reprint]
Creticos PS, Schroeder JT, Hamilton RG, Alcer-Whaley SL, Bhattignavong AP, Lindblad R, Hoffman R, Seyfert V, Eiden JJ, Broide D, Immune Tolerance Network Group (2006): Immunotherapy with a Ragweed–Toll-Like Receptor 9 Agonist Vaccine for Allergic Rhinitis.  New Engl J Med 355: 1445-1455, 2006. [PubMed] [Reprint]
Danke NA, Koelle DM, Yee C, Beheray S, Kwok WW. Autoreactive T cells in healthy individuals. J Immunol 172: 5967-5972, 2004. [PubMed] [Reprint]
Danke NA, Koelle DM, Kwok WW. Persistence of herpes simplex virus type 2 VP16-specific CD4(+) T cells. Hum Immunol 66: 777-87, 2005. [PubMed] [Reprint]
de Jager W, Bourcier K, Rijkers GT, Prakken BJ, Seyfert-Margolis V. Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays. BMC Immunol 10:52, 2009. [PubMed] [Reprint]
Derks RA, Jankowska-Gan E, Xu Q, Burlingham WJ. Dendritic cell type determines the mechanism of bystander suppression by adaptive T regulatory cells specific for the minor antigen HA-1. J Immunol 179: 3443-51, 2007. [PubMed] [Reprint]
Devendra D, Eisenbarth GS. Interferon alpha - a potential link in the pathogenesis of viral induced Type 1 diabetes and autoimmunity. Clin Immunol 111: 225-33, 2004. [PubMed] [Reprint]
Devendra D, Liu E, Eisenbarth GS. Type 1 diabetes: recent developments. Brit Med J 328:750-754, 2004. [PubMed] [Reprint]
Diamond B, Bluestone J, Wofsy D. The immune tolerance network and rheumatic disease: immune tolerance comes to the clinic. Arthritis Rheum 44:1730-5, 2001. [PubMed] [Reprint]
Ding R, Li B, Muthukumar T, Dadhania D, Medeiros M, Hartono C, Serur D, Seshan SV, Sharma VK, Kapur S, and Suthanthiran M. CD103 mRNA levels in urinary cells predict acute rejection of renal allografts. Transplantation 75: 1307-1312, 2003. [PubMed] [Reprint]
Ding R, Medeiros M, Dadhania D, Muthukumar T, Kracker D, Kong JM, Epstein SR, Sharma VK, Seshan SV, Li B, and Suthanthiran M. Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine. Transplantation 74:987-994, 2002. [PubMed] [Reprint]
Eisenbarth G, Jasinski J. Disease Prevention with Islet Autoantigens. Endocrinology and Metabolism Clinics of North America 2004; 33(1):59-74. [PubMed] [Reprint]
Eisenbarth GS, Gottlieb PA. Autoimmune Polyendocrine Syndromes. New Engl J Med 2004; 350:36-47. [PubMed] [Reprint]
Francis JN, James LK, Paraskevopoulos G, Wong C, Calderon MA, Durham SR, Till SJ. Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activity. J Allergy Clin Immunol 121:1120-1125, 2008. [PubMed] [Reprint]
Fudaba Y, Spitzer TR, Shaffer J, Kawai T, Fehr TI, Delmonico F, Preffer F, Tolkoff-Rubin N, Dey B, Saidman SL, Kraus A, Bonnefoix T, McAfee S, Kattleman K, Colvin RB, Sachs DH, Cosimi AB, Sykes M. Myeloma responses and tolerance following combined kidney and non-myeloablative marrow transplantation: in vivo and in vitro analyses.  Am J Transplant 6: 2121-2133, 2006. [PubMed] [Reprint]
Game DS, Hernandez-Fuentes MP, Lechler RI. Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro. Am J Transplant 3: 454-64, 2005. [PubMed] [Reprint]
Gebauer BS, Hricik DE, Atallah A, Bryan K, Riley J, Tary-Lehmann M, Greenspan NS, Boehm BO, Hering BJ, Heeger PS. Evolution of the Enzyme-Linked Immunosorbent Spot Assay for post-transplant alloreactivity as a potentially useful immune monitoring tool. Am J Transplantation 2:857-866, 2002. [PubMed] [Reprint]
Giannoni F, Barnett J, Bi K, Samodal R, Lanza P, Marchese P, Billetta R, Vita R, Klein MR, Prakken B, Kwok WW, Sercarz E, Altman A, Albani S. Clustering of T cell ligands on artificial APC membranes influences T cell activation and protein kinase C theta translocation to the T cell plasma membrane. J Immunol 174: 3204-11, 2005. [PubMed] [Reprint]
Gonzalez JC, Kwok WW, Wald A, McClurkan CL, Huang J, Koelle DM. Expression of cutaneous lymphocyte-associated antigen and E-selectin ligand by circulating human memory CD4+ T lymphocytes specific for herpes simplex virus type 2. J Infect Dis 191: 243-54, 2005. [PubMed] [Reprint]
Grant J, Bourcier K, Wallace S, Pan D, Conway A, Seyfert-Margolis V, Wallace PK. Validated protocol for FoxP3 reveals increased expression in type 1 diabetes patients. Cytometry B Clin Cytom 76B: 69-78, 2009. [PubMed] [Reprint]
Hahne F, Khodabakhshi AH, Bashashati A, Wong CJ, Gascoyne RD, Weng AP, Seyfert-Margolis V, Bourcier K, Asare A, Lumley T, Gentleman R, Brinkman RR. Per-channel basis normalization methods for flow cytometry data. Cytometry A 77:121-31, 2010. [PubMed] [Reprint]
Hernandez-Fuentes MP, Lechler RI. Chronic graft loss: Immunological and non-immunological factors. In "Kidney Transplantation: Strategies to Prevent Organ Rejection. Ronco C., Chiaramonte S., Remuzzi G (eds). Contrib Nephrol, Basel , Karger, 146: 54-64, 2005. [PubMed]
Herold KC, Gitelman S, Greenbaum C, Puck J, Hagopian W, Gottlieb P, Sayre P, Bianchine P, Wong E, Seyfert-Margolis V, Bourcier K, Bluestone JA; Immune Tolerance Network ITN007AI Study Group. Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years. Clin Immunol 132: 166-173, 2009. [PubMed] [Reprint]
Hoffenberg EJ, Emery LM, Barriga KJ, Bao F, Taylor J, Eisenbarth GS et al. Clinical features of children with screening-identified evidence of celiac disease. Peds 113:1254-1259, 2004. [PubMed] [Reprint]
Huan J, Culbertson N, Spencer L, Bartholomew R, Burrows GG, Chou YK, Bourdette D, Ziegler SF, Offner H, Vandenbark AA. Decreased Foxp3 levels in multiple sclerosis patients. J Neurosci Res 81: 45-52, 2005. [PubMed] [Reprint]
Kawai, T, Cosimi AB, Spitzer TR, Tolkoff-Rubin, N, Suthanthiran M, Saidman SL, Shaffer J, Preffer FI, Ding R, Sharma V, Fishman JA, Dey B, Ko DSC, Hertl M, Goes NB, Wong W, Williams WW, Colvin RB, Sykes M, Sachs DH. HLA-Mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 358: 353-61, 2008. [PubMed] [Reprint]
Klunker S, Saggar LR, Seyfert-Margolis V, Asare AL, Casale TB, Durham SR, Francis JN; Immune Tolerance Network Group. Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding. J Allergy Clin Immunol 120: 688-95, 2007. [PubMed] [Reprint]
Knechtle SJ, Pascual J, Bloom DD, Torrealba JR, Jankowska-Gan E, Burlingham WJ, Kwun J, Colvin RB, Seyfert-Margolis V, Bourcier K, Sollinger HW. Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring. American Journal of Transplantation 9: 1087-1098, 2009. [PubMed] [Reprint]
Lee JA, Spidlen J, Boyce K, Cai J, Crosbie N, Dalphin M, Furlong J, Gasparetto M, Goldberg M, Goralczyk EM, Hyun B, Jansen K, Kollmann T, Kong M, Leif R, McWeeney S, Moloshok TD, Moore W, Nolan G, Nolan J, Nikolich-Zugich J, Parrish D, Purcell B, Qian Y, Selvaraj B, Smith C, Tchuvatkina O, Wertheimer A, Wilkinson P, Wilson C, Wood J, Zigon R; International Society for Advancement of Cytometry Data Standards Task Force, Scheuermann RH, Brinkman RR. MIFlowCyt: the minimum information about a Flow Cytometry Experiment. Cytometry A 73:926-30, 2008. [PubMed] [Reprint]
Liu E, Eisenbarth GS. Accepting clocks that tell time poorly: fluid-phase versus standard ELISA autoantibody assays. Clin Immunol 125:120-126, 2007. [PubMed] [Reprint]
Mallone R, Kochik SA, Laughlin EM, Gersuk VH, Reijonen H, Kwok WW, Nepom GT. Differential recognition and activation thresholds in human autoreactive GAD-specific T-cells. Diabetes 53: 971-977, 2004. [PubMed] [Reprint]
Mallone R, Kochik SA, Reijonen H, Carson B, Ziegler SF, Kwok W, Nepom GT. Functional avidity directs T-cell fate in autoreactive CD4+ T-cells. Blood 102: 4103-8, 2005. [PubMed] [Reprint]
Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, ITN/JDRF Type 1 Diabetes Combination Therapy Assessment Group.  Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN–JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin. Exp. Immunol. 160: 176-184, 2010. [Reprint]
Matthews JB, Ramos E, Bluestone JA. Clinical trials of transplant tolerance: slow but steady progress. Am J Transplant 3:794-803, 2003. [PubMed] [Reprint]
Maus MV, Kovacs B, Kwok WW, Nepom GT, Schlienger K, Riley JL, Allman D, Finkel TH, June CH. Extensive replicative capacity of human central memory T cells. J Immunol 172: 6675-6683, 2004. [PubMed] [Reprint]
Mazariegos GV, Zahorchak AF, Reyes J, Ostrowski L, Flynn B, Zeevi A, Thomson AW. Dendritic cell subset ratio in peripheral blood correlates with successful withdrawal of immunosuppression in liver transplant patients. Am J Transplant 3:689-96, 2003. [PubMed] [Reprint]
Miao D, Yu L, Tiberti C, Cuthbertson DD, Rewers MJ, DiMario U, Eisenbarth GS, Dotta F. ICA512(IA-2) Epitope Specific Assays Distinguish Transient from Diabetes Associated Autoantibodies. J Autoimmun 2002; 18:191-6. [PubMed] [Reprint]
Miao D, Yu L, Eisenbarth GS. Role of autoantibodies in type 1 diabetes. Front Biosci 12:1889-1898, 2007 [PubMed] [Reprint]
Muthukumar T, Dadhania D, Ding R, Snopkowski C, Naqvi R, Lee JB, Hartono C, Li B, Sharma VK, Seshan SV, Kapur S, Hancock WW, Schwartz JE, Suthanthiran M. Messenger RNA for FOXP3 in the urine of renal allograft recipients. New Engl J Med 353: 2342-51, 2005. [PubMed] [Reprint]
Muthukumar T, Ding R, Dadhania D, Medeiros M, Li B, Sharma VK, Hartono C, Serur D, Seshan S, Volk H-D, Reinke P, Kapur S, and Suthanthiran M. Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts. Transplantation 75: 1565-1570, 2003. [PubMed] [Reprint]
Nepom, G. T. MHC multimers: expanding the clinical toolkit Clin. Immunol. 106:1-4, 2003. [PubMed] [Reprint]
Newell KA, Asare A, Kirk AD, Gisler TD, Bourcier K, Suthanthiran M, Burlingham WJ, Marks WH, Sanz I, Lechler RI, Hernandez-Fuentes MP, Turka LA, Seyfert-Margolis VL. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest 120: 1836-1847, 2010. [PubMed] [Reprint]
O'Connor MJ, Shankar RD, Parrish DB, Das AK. Knowledge-data integration for temporal reasoning in a clinical trial system. Int J Med Inform. 78:S77-85, 2009. [PubMed] [Reprint]
Offner H, Vandenbark AA. Congruent effects of estrogen and T cell receptor peptide therapy on regulatory T cells in EAE and MS. Intl Rev Immunol 24:447-477, 2005. [PubMed]
Orban T, Farkas K, Jalahej H, Kis J, Treszl A, Falk B, Reijonen H, Wolfsdorf J, Ricker A, Matthews JB, Tchao N, Sayre P, Bianchine P. Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy. J Autoimmun. 34: 408-415, 2010. [PubMed] [Reprint]
Porcheray F, Wong W, Saidman SL, De Vito J, Girouard TC, Chittenden M, Shaffer J, Tolkoff-Rubin N, Dey BR, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Zorn E. B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am J Transplant 9: 2126-35, 2009. [PubMed] [Reprint]
Reijonen, H. and Kwok, W. W. Use of HLA class II tetramers in tracking antigen-specific T cells and mapping T-cell epitopes. Methods 29:282-288, 2003. [PubMed] [Reprint]
Rotrosen D, Matthews JB, Bluestone JA. The immune tolerance network: a new paradigm for developing tolerance-inducing therapies. J Allergy Clin Immunol 110:17-23, 2002. [PubMed] [Reprint]
Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Bourcier K, Sharif A, Krajewska M, Lord GM, Roberts I, Goldman M, Wood KJ, Newell K, Seyfert-Margolis V, Warrens AN, Janssen U, Volk HD, Soulillou JP, Hernandez-Fuentes MP, Lechler RI. Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest 120: 1848-1861, 2010. [PubMed] [Reprint]
Saxon, A. What impact will the Immune Tolerance Network have on the future treatment of allergic diseases? Clin Exp Allergy 34: 1657-1659, 2004. [PubMed] [Reprint]
Seyfert-Margolis V, Turka LJ. Marking a path to transplant tolerance [Commentary]. J Clin Invest 118:2684-6, 2008. [PubMed] [Reprint]
Seyfert-Margolis V, Gisler TD, Asare AL, Wang RS, Dosch HM, Brooks-Worrell B, Eisnenbarth GS, Palmer JP, Greenbaum CJ, Gitelman SE, Nepom GT, Bluestone JA, Herold KC. Analysis of T cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled study. Diabetes 55: 2588-94, 2006. [PubMed] [Reprint]
Shamji MH, Wilcock LK, Wachholz PA, Dearman RJ, Kimber I, Wurtzen PA, Larché M, Durham SR, Francis JN. The IgE-facilitated allergen binding (FAB) assay: validation of a novel flow-cytometric based assay for the detection of inhibitory antibody responses. J Immunol Meth 317: 71-9, 2006. [PubMed] [Reprint]
Shankar RD, Martins SB, O'Connor MJ, Parrish DB, Das AK. Representing and Reasoning with Temporal Constraints in Clinical Trials Using Semantic Technologies. In: Biomedical Engineering Systems and Technologies, Springer Berlin Heidelberg, Fred A, Filipe J, Gamboa H, Editors, pp 520-530, 2009. [Reprint]
Shapiro AMJ, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, Secchi A'Brendel MD, Berney T, Brennan DC, Cagliero E, Alejandro R, Ryan EA, DiMercurio B, Morel P, Polonsky KS, Reems J, Bretzel RG, Bertuzzi F, Froud T, Kandaswamy R, Sutherland DER, Eisenbarth G, Segal M, Preksaitis J, Korbutt GS, Barton FB, Viviano L, Seyfert-Margolis V, Bluestone J, and Lakey JRT (2006): International Multicenter Trial of Islet Transplantation with the Edmonton Protocol in Type 1 Diabetes.  New Engl J Med 355: 1318-1330, 2006. [PubMed] [Reprint]
Srikantha M, Sergeant R, Khan T, Lechler RI, Davey N, Hernandez-Fuentes MP, Warrens AN. Retrospective tissue typing of the kidney donor from recipient urine. Kidney Int 74:952-5, 2008. [PubMed] [Reprint]
St. Clair EW, Turka LA, Saxon A, Matthews JB, Sayegh MH, Eisenbarth GS, Bluestone J. New reagents on the horizon for immune tolerance. Ann Rev Medicine 58:329–46, 2007. [PubMed] [Reprint]
Thomson AW, Mazariegos GV, Reyes J, Donnenberg VS, Donnenberg AD, Bentlejewski C, Zahorchak AF, O'Connell PJ, Fung JJ, Jankowska-Gan E, Burlingham WJ, Heeger PS, Zeevi A. Monitoring the patient off immunosuppression: Conceptual framework for a proposed tolerance assay study in liver transplant recipients. Transplantation 72:S13-22, 2001. [PubMed] [Reprint]
Vandenbark AA, TCR peptide vaccination in multiple sclerosis: boosting a deficient natural regulatory network that may involve TCR-specific CD4+CD25+ Treg cells. Current Drug Targets – Inflammation & Allergy 4: 217-229, 2005. [PubMed]
Vandenbark AA, Culbertson NE, Bartholomew RM, Huan J, Agotsch M, LaTocha D, Yadav V, Mass M, Whitham R, Lovera J, Milano J, Theofan G, Chou YK, Offner H, Bourdette DN. Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis. Immunology 123: 66-78, 2008. [PubMed] [Reprint]
Vandenbark AA, Culbertson NE. Trivalent T cell receptor peptide vaccine for treatment of multiple sclerosis targets predominant V genes widely implicated in autoimmune diseases and allergy. In: Immune Regulation and Immunotherapy in Autoimmune Disease. Zhang J, ed. Springer Life Sciences, pp 369-408, 2007. [PubMed]
Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Guttmann CRG, Rusche JR, Khoury SJ. CTLA4Ig treatment in patients with multiple sclerosis: An open-label, phase 1 clinical trial. Neurology 71: 917-924, 2008 [PubMed] [Reprint]
Wang J, Miao D, Babu S, Yu J, Barker J, Klingensmith G, Rewers M, Eisenbarth GS, and Yu L. Prevalence of autoantibody-negative diabetes is not rare at all ages and increases with older age and obesity. J Clin Endocrinol Metab 92:88-92, 2007. [PubMed] [Reprint]
Xu Q, Lee J, Jankowska-Gan E, Schultz J, Roennburg DA, Haynes LD, Kusaka S, Sollinger HW, Knechtle SJ, Vanbuskirk AM, Torrealba JR, Burlingham WJ. Human CD4+CD25low Adaptive T Regulatory Cells Suppress Delayed-Type Hypersensitivity during Transplant Tolerance. J Immunol 178: 3983-3995, 2007. [PubMed] [Reprint]
Yang J, Jaramillo A, Shi R, Kwok WW, Mohanakumar T. In vivo biotinylation of the major histo-compatibility complex (MHC) class II/peptide complex by co-expression of BirA enzyme for the generation of MHC class II/tetramers. Hum Immunol 65: 692-699, 2004. [PubMed] [Reprint]
Yu J, Steck AK, Babu S, Yu L, Miao D, McFann K, Hutton J, Eisenbarth GS, Klingensmith G. Single nucleotide transcription factor 7-like 2 (TCF7L2) gene polymorphisms in antiislet autoantibody-negative patients at onset of diabetes. J Clin Endocrinol Metab 94:504-10, 2009 [PubMed] [Reprint]
Yu J, Steck AK, Babu S, Yu L, Miao D, McFann K, Hutton J, Eisenbarth GS, Klingensmith G. Single nucleotide transcription factor 7-like 2 (TCF7L2) gene polymorphisms in antiislet autoantibody-negative patients at onset of diabetes. J Clin Endocrinol Metab 94:504-10, 2009 [PubMed] [Reprint]
Yu L, Wang J, O'Dell JR, Oates J, Arend WP, Eisenbarth GS. Anti-dsDNA antibody assay: high specificity and sensitivity with a filtration radioassay in comparison to low specificity with the standard ELISA. J Rheumatol 34:734-739, 2007. [PubMed] [Reprint]
Zhang L, Barker JM, Babu S, Su M, Stenerson M, Cheng M et al. A robust immunoassay for anti-interferon autoantibodies that is highly specific for patients with autoimmune polyglandular syndrome type 1. Clin Immunol 125:131-137, 2007. [PubMed] [Reprint]

Highlighted Meeting Abstracts

Anantharaman P, Dadhania D, Muthukumar T, Aull M, Seshan S, Hartono C, Serur D, Ding R, Li B, Kapur S, and Suthanthiran M. Measurement of mRNA for granzyme B in urine in the first week of renal transplantation predicts clinical as well as histological outcome. (Abstract #1129) American Transplant Congress, Washington, DC, May 30 - Jun 4, 2003. [Abstract]
Anantharaman P, Dadhania D, Muthukumar T, Aull M, Seshan S, Hartono C, Serur D, Ding R, Li B, Suthanthiran M, Kapur S. Noninvasive surrogate for protocol biopsies of renal allografts and a mechanistic guide for the weaning of immunosuppressive therapy. (Abstract #1158) American Transplant Congress, Washington, DC, May 30 - Jun 4, 2003. [Abstract]
Andreola G, Chittenden M, Shaffer J, Cosimi AB, Kawai T, Cotter P, Dey BR, Tolkoff-Rubin N, Preffer F, Saidman S, Kattleman K, Spitzer TR, Sachs DH, Sykes M Mechanisms of Donor-Specific Unresponsiveness Following Loss of Chimerism in Recipients of Haploidentical Combined Bone Marrow/Kidney Transplantation . FOCIS 2009, San Francisco, CA, June 11-14, 2009. [Abstract]
Asare A, Gao Z, Wang R, Carey V, Seyfert-Margolis V Gene expression quality assurance algorithm improves statistical power in clinical immune tolerance studies. Immunology and Gene Expression, Cold Spring Harbour, NY, April 22-26, 2008. [Abstract]
Asare AL, Kolchinsky SA, Wood P, Seyfert-Margolis VL. Comparison of RNA Preparation Methods and Their Effect on Cytokine/Chemokine Gene Expression. (Abstract #Su1.60) 2005 Meeting of the Federation of Clinical Immunology Societies, Boston, MA, May 12-16, 2005. [Abstract]
Bourcier K, Grant J, Liu Z, Wallace S, Wallace P, Seyfert-Margolis V. Optimizing preparation and shipping of blood samples from multi-site clinical trials to a central core facility for flow cytometric analysis. XXV Congress of the International Society for hte Advancement of Cytometry, Seattle, WA, May 8-12, 2010. [Abstract]
Boyce K, Spencer T. Using automated extract, transform and load (ETL) processes to build an integrated warehouse of clinical and mechanistic results in immunology-based trials. American Medical Informatics Association Symposium Spring Congress, Phoenix, AZ, May, 2006. [Abstract]
Brooks-Worrell BM, Dosch HM, Herold K, Seyfert V, Greenbaum CJ, Gitelman SE, Palmer JP. Marked Differences in T Cell Reactivity in Recently Diagnosed Type 1 Diabetes Patients Versus Controls. (Abstract #2778) XXIIth International Congress of Immunology, Montreal, Canada, July 18-23, 2004. [Abstract]
Burlingham WJ, Jankowska-Gan E, Gawin D, Haynes L, Knechtle S, Djamali A. 4 Yr Follow-Up of an ITN-Sponsored, Alemtuzimab-Based Tolerance Induction Trial: Donor-Specific Regulation [DSR] Identifies Renal Transplants with Superior Outcome. (Abstract #1563) 2010 American Transplant Congress, San Diego, CA, May 1-5, 2010. [Abstract]
Carreno M, Ciancio G, Burke GW, Cirocco R, Gomez C, Salma F, Mathew J, Jin Y, Miller J, Esquenazi V. Precursor dendritic cell subsets in kidney allograft recipients after induction with alemtuzumab (C1H) vs thymoglobulin (Thy) vs daclizumab (Dac) vs A C1H recipient given donor specific stem cells (DHSC). ASHI 31st Annual Meeting, San Diego, CA, October 17, 2006. [Abstract]
Carreno M, Cirocco R, Mathew J, Ciancio G, Burke GW, Miller J, Esquenazi V. T regulatory cells after induction therapy with Campath-1H, vs Thymoglobulin vs Daclizumab in kidney transplant recipients. American Transplant Congress, Seattle, WA, May 21, 2005. [Abstract]
Carreno MR, Ciancio G, Burke GW, Cirocco R, Salman F, Mathew J, Jin Y, Miller J, Esquenazi, V. Precursor dendritic cell subsets in kidney allograft recipients after induction with alemtuzumab (C1H) vs Thymoglobulin (Thy) vs Daclizumab (Dac) vs a C1H recipient given donor specific stem cells (DHSC). ASHI 31st Annual Meeting, Washington, DC, Oct 17-21, 2005. [Abstract]
Casale TB, Kline JN, Busse WW, Ballas ZK, Mokhtarani M, Seyfert-Margolis V, Bateman K, Moss MH, Townley RG. Omalizumab pretreatment prevents allergic reactions due to rush immunotherapy (RIT). (Abstract #259) AAAAI Annual Meeting, San Antonio, TX, March 18-22, 2005. [Abstract]
Casale TB. Anti-IgE monoclonal antibody administered with immunotherapy (Stanislaus Jaros Lecture). American College of Allergy, Asthma and Immunology (ACAAI), Boston, MA, Nov 4-9, 2004. [Abstract]
Casale TB. Omalizumab And Immunotherapy. American College of Allergy, Asthma and Immunology (ACAAI), Boston, MA, Nov 4-9, 2004. [Abstract]
Cirocco R, Careno M, Mathew J, Valone T, Esquenazi V, Miller J. Increased production of the regulatory T-cell transcription factor Fox P-3m-RNA and CD4+CD25+ cells in Campath-1H and donor hematopoetic stem cell treated kidney transplant recipients. ASHI 31st Annual Meeting, Washington, DC, Oct 17-21, 2005. [Abstract]
Cirocco R, Carreno M, Mathew J, Vallone T, Rosen A, Burke GW, Ciancio G, Kleiner G, Esquenazi V, Miller J. Upregulation of FOXP3 in renal transplantation after antibody induction regimens with and without bone marrow or stem cell infusions. World Transplant Congress, Boston, MA, July 22-27, 2006. [Abstract]
Collin F, Asare AL, Kolchinsky SA, Speed TP, Seyfert-Margolis VL. NUSE and RLE: Quality assessment of oligonucleotide microarray data to quantify systemic variation. (Abstract #Su2.110) 2005 Meeting of the Federation of Clinical Immunology Societies, Boston, MA, May 12-16, 2005. [Abstract]
Cornell LD, Della Pelle P, Brousiadies N, Collins AB , Colvin RB. Endothelial response to rejection: Enhanced expression of complement regulatory proteins decay accelerating factor (DAF, CD55) and protectin (CD59) in human renal allografts. Mod Pathol , 17, 285A, 2008. [Abstract]
Creticos PS, Eiden JJ, Broide D H, Balcer-Whaley, SL, Schroeder, JT, Khattignavong, A, Li H, Norman P, Hamilton, R. Immunotherapy with immunostimulatory oligonucleotides linked to purified ragweed amb a 1 allergen: Effects on antibody production, nasal allergen provocation, and ragweed seasonal rhinitis. 58th AAAAI, New York, NY, March 1-3, 2002. [Abstract]
Creticos PS, Lighvani SS, Bieneman AP, Balcer-Whaley SP, Norman PS, Lichtenstein LM, Schroeder JY. Enhanced IL10 Secretion by PBMC During the Ragweed Season: Effects of AIC Immunotherapy vs Placebo. (Abstract #530) 60th Meeting of the AAAAI, Denver, CO, Mar 3-7, 2003. [Abstract]
Creticos, PS, Eiden JJ, Broide DH, Balcer-Whaley SL, Schroeder JT, Khattignavong A, Li H. Norman P, Hamilton R. Immunotherapy with Immunostimulatory Oligonucleotides Linked to Purified Ragweed Amb a 1 Allergen: Effects on Nasal Allergen Provocation, Antibody Production, and Seasonal Rhinitis Endpoints. 24th Symposium of Collegium Internationale Allergoligicum, Bermuda, November 1, 2002. [Abstract]
Dadhania D, Muthukumar T, Anantharaman P, Ding R, Seshan S, Li B, Aull M, Hartono C, Serur D, Kapur S, Suthanthiran M. mRNA profiles of urinary cells distinguish allograft infiltrates associated with acute rejection from infiltrates that do not cause proximate acute rejection. (Abstract #48) American Transplant Congress, Washington, DC, May 30 - Jun 4, 2003. [Abstract]
Demetris AJ, Ruppert K, Ekong U, Rosenthal P, Sayre P, Tchao N, Feng S. Morphometric and Histopathologic Analysis of Protocol Biopsies from Stable, Long-Surviving Pediatric Recipients of Living-Related Liver Allografts: A Comparison to Liver Age and Sex-Matched Controls. (Abstract #909) American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
Du Toit G, Roberts G, Sayre P, Turcanu V, Fisher HR, Broide D, Nirenstein L, Radulovic S, Stephens A, Seyfert-Margolis V, Nasser N, Murphy S, The Immune Tolerance Network ITN032AD Study Group, Lack G Induction Of Tolerance Through Early Introduction Of Peanut In High-Risk Children, The LEAP Study. (Abstract #84) 2010 AAAAI Annual Meeting, New Orleans, LA, February 26 - March 2, 2010. [Abstract]
Eisenbarthh GS. Autoantibodies in type 1 diabetes and neurological disorders. XXIIth International Congress of Immunology, Montreal, Canada, July 18-23, 2004. [Abstract]
Emmanuelle Waubant, Daniel Pelletier, Michele Mass, Jeff Cohen, Mariko Kita, Anne Cross, Amit Bar-Or, Timothy Vollmer, Michael Racke, Olaf Stuve, Steven Schwid, Andrew Goodman, Norman Kachuck, Jana Preiningerova, Bianca Weinstock-Guttman, Peter Calabresi, Aaron Miller, Masoud Mokhtarani, David Iklé, Linna Ding, Ellen Rosenberg, ITN020AI Study Management Team, Collin Spencer and Scott S. Zamvil Atorvastatin therapy in patients with Clinically Isolated Syndrome (CIS) and High Risk for Conversion to Multiple Sclerosis (MS): the STAyCIS study. ECTRIMS, Dusseldorf, Germany, September 9-12, 2009. [Abstract]
Farris AB, Taheri D, Iafrate AJ, Smith RN, Collins AB, Tolkoff-Rubin N, Spitzer TR, Kawai T, Cosimi AB, Sachs DH, Colvin RB Renal pathology of the engraftment syndrome in recipients of combined kidney and bone marrow allografts. US & Canadian Academy of Pathology, Washington, DC, March 20-26, 2010. [Abstract]
Feng S, Ekong U, Lobritto S, Demetris A, Rosenthal P, Alonso E, Tchao N ITN029ST: Immunosuppression Withdrawal in Pediatric Recipients of Parental Living Donor Liver Transplants: Preliminary Results of a Pilot Study. (Abstract #189) American Transplant Congress, Boston, MA, May 30 - Jun 3, 2009. [Abstract]
Francis JN, Saggar LR, Seyfert-Margolis V, Asare AL, Klunker S, Casale TB, Durham SR and Immune Tolerance Network Group. The combination of anti-IgE monoclonal antibody (omalizumab) with ragweed immunotherapy results in enhanced and long-term inhibitory effects on facilitated-antigen presentation. XXVI Meeting of the EAACI, Goteborg, Sweden, June 9-13, 2007. [Abstract]
Francis JN, Wilcock LK, Paraskavopoulos G, Till SJ, Durham SR. Time-course analysis of a Double-Blind Placebo Controlled Trail of Grass Pollen Immunotherapy: increased cellular IL-10 production and reduction in late phase responses precede increased IgG4 and early phase responses. Collegium Internationale Allergologicum, Malta, May 5-10, 2006. [Abstract]
Fudaba Y, Shaffer JM, Kraus A, Cosimi AB, Delmonico FL, Dey B, Kawai T, McAfee S, Preffer F, Tolkoff-Rubin N, Sachs DH, Saidman SL, Spitzer TR, Sykes M. Alloresponses in tolerant recipients of combined kidney/bone marrow transplantation with non-myeloablative conditioning. (Abstract #P931) International Congress of Transplantation, Vienna, Austria, Sept 5-10, 2004. [Abstract]
Fudaba Y, Shaffer JM, Kraus A, Cosimi AB, Delmonico FL, Dey B, Kawai T, McAfee S, Preffer F, Tolkoff-Rubin N, Sachs DH, Saidman SL, Spitzer TR, Sykes M. Alloresponses in tolerant recipients of combined kidney/bone marrow transplantation with non-myeloablative conditioning. (Abstract #640) American Transplant Congress, Washington, DC, May 30 - Jun 4, 2003. [Abstract]
Garcia-Morales RO, Esquenazi V, Kleiner G, Cirocco RE, Burke GW, Carreno MR, Ciancio G, Kenyon NS, Ricordi C, Tzakis AG, Shariatmadar S, Miller J. Comparative chimerism levels in cadaver and living related donor whole bone marrow infused kidney recipients vs. a 2X stem cell-infused recipient treated with alemtuzumab. th Basic Science Symposium of the International Transplantation Society, La Baule, France, June 19-23, 2005. [Abstract]
Hamilton RG, Hovanec-Burns D, Bourcier K, Lack G, Francis GN, Aalberse RC, Durham SR, Seyfert-Margolis V. Allergen-specific IgG and IgG4 autoanalyzer performance and utility in assessing immunotherapy study specimens. Annual Meeting of the AAAAI, Philadelphia, PA, March 14-18, 2008. [Abstract]
Haynes LD, Jankowska-Gan E, Seyfert-Margolis VL, Newell KA, Turka LA, Asare A, Bourcier KD, Burlingham WJ. Donor Specific Regulation and B Cell Tolerance Signature in Renal Transplant Recipients.. (Abstract #1578) 2010 American Transplant Congress, San Diego, CA, May 1-5, 2010. [Abstract]
Heeger PS, Gebrauer B, Schulak JA, Tary-Lehmann M, Greenspan N, Hricik DE. Post transplant immune monitoring by elispot reveals differences between patients with and without acute rejection. (Abstract #1067) American Transplant Congress, Washington, DC, Apr 25 - May 1, 2002. [Abstract]
Hernandez-Fuentes Biomarkers of tolerance: clinical interest. III Jornada de Inmunospresion Clinica y Experimental en Transplantes (ICET), Madrid, Spain, 22 January, 2009. [Abstract]
Hernandez-Fuentes M, Perucha E, Sagoo P, Ballow AA, Hilton R, Sergeant R, Waters J, Roberts I, Wood KJ, Warrens AN, Lechler R. Post-transplant detection of anti-HLA antibodies: risk factors and clinical relevance.. British Renal Association, Glosgow, Scotland, May, 2008. [Abstract]
Hernandez-Fuentes M, Perucha E, Sagoo P, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Brouard S, Giral M, Seyfert-Margolis V, Newell K, Turka L, Goldman M, Wood K, Warrens A, Volk HD, Soulillou JP, Janssen U, Lechler RI, www.transplant-tolerance.org.uk/ParticipantPhysicians.aspx Validated Biomarkers of Immune Tolerance in Renal Transplants. (Abstract #1561) American Transplant Congress, Boston, MA, May 30 - Jun 3, 2009. [Abstract]
Hernandez-Fuentes M, Sagoo P, Perucha E, Sawitzki B, Miqueu P, Craciun L, Sergeant R, Ballow A, Chapman S, Tomiuk S, Roberts I, Stephens D, Janssen U, Wood K, Warrens A, Goldman M, Soulillou JP, Volk HD, Lechler RI Tools to detect Immunological Tolerance in renal transplants. AST Distinguished Fellows Research Forum, San Diego, CA, April, 2008. [Abstract]
Hernandez-Fuentes M, Sagoo P, Perucha E, Sawitzki B, Miqueu P, Craciun L, Sergeant R, Ballow A, Chapman S, Tomiuk S, Roberts I, Stephens D, Janssen U, Wood K, Warrens A, Goldman M, Soulillou JP, Volk HD, Lechler RI. Tools to detect immunological tolerance in renal transplants. . AST Distinguished Fellows Research Forum, San Diego, CA, , 2007. [Abstract]
Hernandez-Fuentes M, Sagoo P, Sawitzki B, Perucha E, Jimenez-Vera E, Craciun L, Brouard S, Chapman S, Janssen U, Warrens AN, Goldman M, Volk HD, Soulillou JP, Wood K, Lechler RI. Tregs in peripheral blood of clinically defined groups of renal transplant recipients. British Society of Immunology, , February, 2007. [Abstract]
Hernandez-Fuentes M, Sawitzki B, Perucha E, Sagoo P, Miqueu P, Chapman S, Stephens D, Craciun L, Roberts I, Hilton R, Sergeant R, Tomiuk S, http://www.transplant-tolerance.org.uk/Participant%20 Physicians.aspx, Janssen U, Goldman M, Soulillou JP, Warrens A, Wood K, Volk HD, Lechler R. Immune tolerance fingerprint in renal transplants. British Transplantation Society, Glasgow, Scotland, April, 2008. [Abstract]
Hernandez-Fuentes MP, Sagoo P, Jimenez E, Rovis F, Stevenson S, Warrens A, Lechler R. Immune Monitoring in Renal Transplantation. British Society of Immunology, Harrogate, UK, December, 2005. [Abstract]
Hernandez-Fuentes MP, Sagoo P, Jimenez-Vera E, Rovis F, Waters J, Hilton R, Warrens AN, Lechler R. Indices of immunological tolerance in renal transplantation: Interim analysis. (Abstract #123) 9th Congress of the British Transplantation Society, Seattle, Washington, March 29-31, 2006. [Abstract]
Hernandez-Fuentes MP, Sawitszki B, Sagoo P, Flavia R, Jimenez E, , Perucha E, Le Moine A, Craciun L, Peters B, Braudeau C, Brouard S, Trzonkowski P, Warnecke G, Chapman S, Libin M, Warrens A, Goldman M, Volk H-D, Soulillou JP, Janssen U, Wood K, Lechler RI. Indices of tolerance: Interim Report. (Abstract #999) World Transplant Congress, Boston, MA, July 22-27, 2006. [Abstract]
Hernandez-Fuentes MP, Sawitzki B, Perucha E, Sagoo P, Miqueu P, Chapman S, Stephens D, Craciun L, Tomiuk S, Brouard S, Giral M, Janssen U, Goldman M, Wood K, Warrens A, Volk HD, Soulillou JP, Lechler RI. Identification of Immune Tolerance in renal transplants. American Transplant Congress, Toronto, Canada, May 31-Jun 4, 2008. [Abstract]
Hernandez-Fuentes MP, Sawitzki B, Sagoo P, Craciun L, Brouard S, Perucha E, Chapman S, Bradeau C, Peters B, Roberts I, Sergeant R, Janssen U, Warrens AN, Wood K, Soulillou JP, Goldman M, Volk HD, Lechler RI, www.transplant-tolerance.org.uk/team.aspx, www.transplant-tolerance.org.uk/physicians/. Biomarkers of tolerance in kidney transplants. American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
Hernandez-Fuentes MP, Sawitzki B, Sagoo P, Perucha E, Craciun L, Giral M, Chapman S, Peters B, Waters J, Roberts I, Sergeant R, Soulillou JP, Wood K, Warrens A, Janssen U, Goldman M, Volk HD, Lechler RI.Participants www.transplant-tolerance.org.uk/team.aspx and Collaborators www.transplant-tolerance.org.uk/physicians/. Indices of tolerance in kidney . The Renal Association Annual Conference, Brighton, UK, May, 2007. [Abstract]
Herold K, Gitelman S, Masharani U, Greenbaum C, Hagopian W, Gottlieb P, Muir A, Ramos E, Tomilin N, Bluestone JA. Treatment with hOKT3γ1(Ala-Ala) improves insulin responses and reduces insulin requirements in patients with new onset Type 1 diabetes (T1DM). (Abstract #271-OR) 64th Scientific Sessions of the American Diabetes Association, Orlando, FL, June 4-8, 2004. [Abstract]
Herold K, Gitelman S, Masharani U, Greenbaum C, Hagopian W, Gottlieb P, Muir A, Ramos E, Tomlin N, Bluestone JA. Treatment with hOKT3γ1(Ala-Ala) improves insulin responses and reduces insulin requirements in patients with new onset Type 1 diabetes (T1DM). (Abstract #1885) XXIIth International Congress of Immunology, Montreal, Canada, July 18-23, 2004. [Abstract]
Herold KA Immune monitoring in Type 1 diabetes: the ITN/TrialNet experience. FOCIS, San Francisco, CA, June 11-14, 2009, 2009. [Abstract]
Herold, KA Immune monitoring in Type 1 diabetes: the ITN/TrialNet experience. FOCIS 2009, San Francisco, CA, June 11-14, 2009. [Abstract]
Hutton GJ, Bowen JD, Forman SJ, Frohman EM, Griffith LM, Kraft GH, Muraro P, Openshaw H, Popat U, Racke M, Sayre P, Stuve O, Wundes A, Nash RA HALT-MS—Intense Immunosuppression and Stem Cell Transplantation for RRMS. 23rd Annual Meeting of the Consortium of MS Centers, Atlanta, GA, 27-30 May, 2009. [Abstract]
ITN Tolerance Assay and Data Analysis Group, the ITN Clinical Trials Group, and the ITN TILT Study Investigators Kinetics of Immune Cell Depletion and Reconstitution with Alemtuzumab: A Possible Explanation for Low Incidence of Opportunistic Infections . (Abstract #1735) American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
ITN Tolerance Assay and Data Analysis Group, the ITN Clinical Trials Group, and the ITN TILT Study Investigators Kinetics of Immune Cell Depletion and Reconstitution with Alemtuzumab: A Possible Explanation for Low Incidence of Opportunistic Infections . (Abstract #1735) American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
Kawai T, Sachs D, Spitzer T, Tolkoff-Rubin N, Saidman S, WilliamsW, Dey B, Goes N, Ko D, Hertl M, Cotter P, Wong W, Colvin R, Sykes M, Cosimi AB Successful Induction of Renal Allograft Tolerance in HLA-Mismatched Kidney Transplant Recipients. FASEB Summer Research Conference, Snowmass, CO, June 3-8, 2006. [Abstract]
Kawai T, Sachs DH, Spitzer T, Sykes M, Tolkoff-Rubin N, Delmonico F, Saidman S, Shaffer J, Dey B, McAfee S, Ko D, Wong W, Williams W, Goes N, Hertl M, Smith RN, Colvin RB , Cosimi AB. Combined kidney and bone marrow transplantation for induction of mixed chimerism and renal allograft tolerance in HLA mismatched transplantation. (Abstract #O112) 20th International Congress of the Transplantation Society, Vienna, Austria, September 5-10, 2004. [Abstract]
Kawai T, Sachs DH, Spitzer T, Sykes M, Tolkoff-Rubin N, Delmonico F, Saidman S, Shaffer J, Dey B, McAfee S, Williams W, Ko D, Hertl M, Goes N, Wong W, Colvin RB, Cosimi AB. Combined kidney and bone marrow transplantation for induction of mixed chimerism and renal allograft tolerance in HLA mismatched transplantation. (Abstract #1217) American Transplant Congress, Boston, MA, May 14-19, 2004. [Abstract]
Kawai T, Sachs DH, Spitzer T, Tolkoff-Rubin N, Delmonico F, Saidman S, Shaffer J, Williams W, Dey B, McAfee S, Ko D, Hertl M, Goes N, Wong W, Fishman JA, Colvin RB, Sykes M, Cosimi B. Combined kidney and bone marrow transplantation for induction of mixed chimerism and renal allograft tolerance in HLA matched and mismatched recipients. (Abstract #1535) American Transplant Congress, Seattle, WA, May 21, 2005. [Abstract]
Kawai T, Sachs DH, Spitzer T, Tolkoff-Rubin N, Ko DSC, Wong W, Williams W, Saidman S, LoCascio S, Colvin RB, Sykes M, Cosimi AB. Progress Report of the MGH/ITN Clinical Trial for Tolerance Induction through Mixed Chimerism in HLA Mismatched Kidney Transplantation. (Abstract #1634) 2010 American Transplant Congress, San Diego, CA, May 1-5, 2010. [Abstract]
Kawai T, Sachs DH, Spitzer T, Tolkoff-Rubin N, Saidman S, Williams W, Dey B, Goes N, Ko D, Wong W, Colvin RB, Sykes M, Cosimi AB. The Long-Term Evaluation of HLA-Mismatched Combined Kidney and Bone Marrow Transplant Recipients after Complete Withdrawal of Immunosuppression. (Abstract #1717) American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
Kawai T, Suthanthiran M, Sharma V, Ding R, Sykes M, Colvin RB, Cosimi AB, Sachs DH. Intragraft RNA Expression of FOXP3 Versus Proinflammatory Cytokines in Tolerant Recipients of HLA Mismatched Renal Allografts. (Abstract #2) American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
Khoury SJ, Bourcier K, Buckle G, Bikowski M, Guttmann C, Rioux P, Jauregui K. Phase I trial of CTLA4Ig treatment in MS. (Abstract #S12.003) 56th American Academy of Neurology, San Francisco, CA, Aprli 24 - May 1, 2004. [Abstract]
Khoury SJ, Viglietta V, Buckle G, Hafler D, Bourcier K, Guttmann C, Bikowski M, Rusche J, Landy H, McNally J, Jauregui K. A Phase I Trial of CTLA4Ig Treatment in MS. (Abstract #S46.004) 57th Annual Meeting of the American Academy of Neurology, Miami Beach, FL, April 9-15, 2005. [Abstract]
Kline JN, Casale TB, Busse WW, Ballas ZK,Mokhtarani M, Bromstead C, Seyfert- Margolis V, Asare A, Bateman K, Moss MH, Townley RG. Omalizumab Plus Rush Immunotherapy (RIT) Is More Effective Than RIT Alone In Preventing Ragweed-Induced Seasonal Allergic Rhinitis (SAR) Symptoms. (Abstract #827) 61st Annual Meeting of the American Academy of Allergy, Asthma and Immunology, San Antonio, TX, March 18-22, 2005. [Abstract]
Klunker S, Francis JN and Durham SR. Ragweed immunotherapy serum inhibits facilitated allergen presentation. 2005 Annual Meeting of the British Society for Allergy & Clinical Immunology, Loughborough, UK, July 18-20, 2005. [Abstract]
Klunker S, Francis JN, Casale TB, Durham SR. Anti-IgE Therapy Inhibits IgE-facilitated Allergen Presentation and Increases the Efficacy of Ragweed Immunotherapy. 2006 AAAAI Annual Meeting, Miami, FL, March 3-7, 2006. [Abstract]
Knechtle S, Bloom D, Pascual J, Torrealba J, Jankowska-Gan E, Bourcier K, Harper L, Seyfert-Margolis V, Colvin R, Sollinger H, Burlingham W. Sirolimus monotherapy in kidney transplantation: Results of an ITN-sponsored trial. (Abstract #134) American Transplant Congress, Toronto, Canada, May 31-Jun 4, 2008. [Abstract]
Knechtle S, Hu H, Janus C, Radke N, Sollinger H, Davis Z, Bloom D. A Tolerance Trial in Kidney Transplantation Based on T-cell Depletion, Tacrolimus, and Sirolimus . American Transplant Congress, San, May 5-9, 2007. [Abstract]
Knechtle SJ, Sollinger HW, Jankowska-Gan E, Burlingham WJ, Bloom DJ. Preliminary results of a tolerance trial in renal transplantation. World Transplant Congress, Boston, MA, July 22-27, 2006. [Abstract]
Kraft GH, Bowen JD, Openshaw H, Forman SJ, Frohman EM, Griffith LM, Hutton GJ, Muraro PA, Popat U, Racke MK, Sayre P, Stuve O, Wundes A, Nash RA. Phase II clinical trial (HALT MS: Immune Tolerance Network) of high dose immunosuppressive therapy (HDIT) and autologous hematopoietic stem cell transplantation (AHSCT) for active relapsing-remitting (RR) multiple sclerosis (MS): Early results.. American Academy of Neurology, Chicago, IL, April 12-19, 2008. [Abstract]
Lakey JRT, Ricordi C, Hering B, DiMercurio B, Lindblad R, O'Neil J, Olack B, Reems JA, Ansite J, Kirlew T, Brandhorst H, Bertuzzi F, Bucher P, Oberholzer J, Ramos E, Viviano L, Shapiro AMJ. Standardization of human islet isolation for an international multi-center transplant trial. (Abstract #571) American Transplant Congress, Washington, DC, May 30 - Jun 4, 2003. [Abstract]
Lakey JRT, Ricordi C, Hering B, DiMercurio B, Lindblad R, Olack B, Reems JA, Ansite J, Brandhorst H, Bertuzzi F, Berney T, Vivano L, O’Neil J, Close N, Shapiro AMJ. Standardization of Human Islet Isolation for a Multi-Center Transplant Trial. (Abstract #P432) 20th International Congress of the Transplantation Society, Vienna, Austria, September 5-10, 2004. [Abstract]
Lakey JRT, Ricordi C, Herring B, Dimercurio B, Lindblad R, Olack B, Reems JA, Ansite J, Brandhorst D, Bertuzzi F, Berney T, Viviano L, O'Neil J, Close N, Shapiro AMJ. Standardization of human islet isolation procedures for a multicenter transplant trial. 64th Scientific Sessions of the American Diabetes Association, Orlando, FL, June 4-8, 2004. [Abstract]
Lim N, Kanaparthi S, Mertens S, Gopalakrishnan N, Gao Z, Liu Z, Bourcier K, Phippard D, Asare A. Quality assessments of un-gated flow cytometry FCS files in a clinical trial setting. XXV Congress of the International Society for hte Advancement of Cytometry, Seattle, WA, May 8-12, 2010. [Abstract]
Liu WH, Szot G, Earle KE, Herold KC, Masharani U, Gitelman SE, Bluestone JA. Immune monitoring: the effects of hOKT3γ1 (Ala-Ala) in a patient with new onset type 1 diabetes mellitus.. (Abstract #Su1.70) Meeting of the Federation of Clinical Immunology Societies, Boston, MA, May 12-16, 2005. [Abstract]
Mathew J, Carreno M, Cirocco R, Rosen A, Vallone T, Garcia-Morales R, Burke GW, Ciancio G, Esquenazi V, Miller J Circulating and graft infiltrating regulatory cells in donor stem cell infused kidney transplant patients treated with alemtuzumab. 12th Innovative Therapeutics in Transplantation Meeting, Nantes, France, June 15, 2006. [Abstract]
Mathew J, Cirocco R, Rosen A, Vallone T, Gomez C, Blomberg B, Fuller L, Burke GW, Ciancio G, Esquenazi V, Miller J. Tolerogenicity of graft infiltrating lymphocytes in donor stem cell infused kidney transplant recipients treated with alemtuzumab. ASHI 31st Annual Meeting, San Diego, CA, October 17, 2006. [Abstract]
Mathew J, Vallone T, Carreno M, Garcia-Morales R, Rosen A, Gomez C, Blomberg B, Fuller L, Burke GW, Ciancio G, Esquenazi V, Miller J. Regulatory cells of donor and recipient phenotypes in donor stem cell infused kidney transplant recipients treated with alemtuzumab. World Transplant Congress, Boston, MA, July 22-27, 2006. [Abstract]
Mathew JM, Vallone T, Carreno M, Rosen A, Gomez C, Garcia-Morales R, Blomberg B, Fuller L, Burke G, Ciancio G, Esquenazi V, Miller J. Regulatory cell development in an LRD-kidney transplant recipient treated with alemtuzumab and donor stem cell infusions (ITN protocol). ASHI 31st Annual Meeting, Washington, DC, Oct 17-21, 2005. [Abstract]
Mazariegos G, Zeevi A, Zahorchuk AF, Ostrowski L, Flynn B, Logar AJ, Dvorchik I, Reyes J, Thomson AW. Myeloid pDC1 is decreased as compared to plasmacytoid pDC2 lineage in peripheral blood of patients successfully withdrawn from immunosuppression after liver transplantation. XIX Int'l Congress Transplantation, Miami, FL, Aug 25-30, 2002. [Abstract]
Mazariegos GV, Zahorchak A, Reyes J, Chapman H, Girnita A, McDade K, Zeevi A, Thompson A. Immunologic Assays in Patients Successfully Withdrawn from Immunosuppression (IS) after Liver Transplantation. (Abstract #521) American Transplant Congress, Boston, MA, May 14-19, 2004. [Abstract]
Mazariegos GV, Zahorchak A, Zeevi A, Flynn B, Logar AJ, Reyes J, Thomson A. Dendritic cell subsets in peripheral blood of patients successfully withdrawn from immunosuppression after liver transplantation (LTx). (Abstract #644) American Transplant Congress, Washington, DC, May 30 - Jun 4, 2003. [Abstract]
Nash RA, Openshaw H, Bowen JD, Forman SJ, Stuve O, Hutton G, Popat U, Kraft G. A Phase II Study of High-Dose Immunosuppressive Therapy (HDIT) Using Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) + Thymoglobulin, and Autologous CD34+ Hematopoietic Stem Cell Transplant (HCT) for treatment of poor prognosis MS: HALT-MS. 22nd Annual Meeting of the CMSC, Denver, CO, May 28-31, 2007. [Abstract]
Newell KA, Asare A, Gisler T, Suthanthiran MS, Burlingham W, Marks W, Turka L, Seyfert-Margolis V. A Unique B cell Signature Associated with Operational Tolerance. American Transplant Congress, Toronto, Canada, May 31-Jun 4, 2008. [Abstract]
Newell KA, Asare A, Kirk AD, Gisler T, Suthanthiran M, Burlingham WJ, Bourcier K, Marks WH, Turka LA, Seyfert-Margolis V. Peripheral B Cell Markers Identify Tolerant Renal Transplant Recipients. (Abstract #LB08) American Transplant Congress, Boston, MA, May 30 - Jun 3, 2009. [Abstract]
Newell KA, Burlingham WJ, Marks WH, Gisler TD, Seyfert VL, Turka LA, Suthanthiran M, Kirk AD. Preliminary Analysis of the ITN Registry of Tolerant Kidney Transplant Recipients. World Transplant Congress, Boston, MA, July 22 – 27, 2006. [Abstract]
O'Connor MJ, Shankar RD, Parrish D, Das AK Knowledge-level Querying of Temporal Patterns in Clinical Research Systems. 12th World Congress on Health (Medical) Informatics, Brisbane, Australia, Aug 20-24, 2007. [Abstract]
O'Connor MJ, Shankar RD, Tu SW, Nyulas CI, Parrish DB, Das AK, Musen MA Using Semantic Web Technologies for Knowledge-Driven Querying of Biomedical Data. 11th Conference on Artificial Intelligence in Medicine (AIME2007), Amsterdam, Netherlands, July 7-11, 2007. [Abstract]
Offner H, Huan J, Bartholomew R, Bourdette D, and Vandenbark A. Expression of the Treg cell associated Foxp3 gene is decreased in MS patients and increases following immunization with a T cell receptor peptide vaccine. 5th Meeting of the European Neurological Society, Vienna, Austria, June 18-22, 2005. [Abstract]
Paraskevopoulos G, Jacobson MR, Carr V, Calderon M, Till SJ, Francis JN, Durham SR. Grass pollen injection immunotherapy: Time course of suppression of allergen-induced late-phase skin responses. J Allergy Clin Immunology, 115, S266, 2005. [Abstract]
Parrish D, McCafferty K. A web-based clinical trials management system: Integration, annotation and deliery of bioinformatics and clinical data within operational workflows of clinical trials. American Medical Informatics Association Spring Congress, Phoenix, AZ, May, 2006. [Abstract]
Parrish D, Raab M. Applying standard data warehousing approaches to biomedical data. BECON/BISTIC 2004 SYMPOSIUM - Biomedical Informatics for Clinical Decision Support: A Vision for the 21st Century, Bethesda, MD, June 21-22, 2004. [Abstract]
Perucha E, Hernandez-Fuentes M, Sagoo P, Hilton R, Sergeant R, Waters J, Warrens AN, Lechler R. Differential effect on CNI treatment in T cell activation on T lymphocytes from renal transplant recipients. British Renal Association, Glasgow, Scotland, May, 2008. [Abstract]
Porcheray F, Wong W, Saidman SL, DeVito J, Girouard TC, Chittenden M, Shaffer J, Tolkoff-Rubin N, Dey BR, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Zorn E. B Cell Immunity in the Context of T Cell Tolerance after Combined Kidney and Bone-Marrow-Transplantation in Humans. (Abstract #307) American Transplant Congress, Boston, MA, May 31-Jun 4, 2009. [Abstract]
Raddassi K, Bourcier K, Estevam J, Gisler T, Hafler DA, Seyfert-Margolis V. Comparison of two methods CPT and Ficoll to isolate mononuclear cells from peripheral blood. Effect on viability and function of freshly and cryopreserved PBMCs. FOCIS Annual Meeting, San Francisco, CA, June 1-5, 2006. [Abstract]
Raddassi K, Bourcier K, Estevam J, Hafler DA, Seyfert-Margolis V. Effect of freezing/thawing conditions and their optimization for quality control of PBMC viability and functional assays . (Abstract #Su1.106) 2005 Meeting of the Federation of Clinical Immunology Societies, Boston, MA, May 12-16, 2005. [Abstract]
Raddassi K, Bourcier K, Estevam J, Seyfert-Margolis V, Hafler D. Elifacs a multiplex assay to detect antigen specific T cells and to monitor the immune response. FOCIS, San Diego, CA, June 7-11, 2007. [Abstract]
Raddassi K, Bourcier K, Estevam J, Seyfert-Margolis V, Hafler D. Improving elispot to detect antigen specific T cells. FOCIS, San Diego, CA, June 7-11, 2007. [Abstract]
Raddassi K, Yang J, Kent S, Bourcier K, Bradshaw E, Seyfert-Margolis V, Kwok W, Hafler DA Detection of myelin reactive CD4+ cells in the peripheral blood of patients with multiple sclerosis using MHC class II tetramers. FOCIS 2009, San Francisco, CA, June 11-14, 2009. [Abstract]
Roberts G, Du Toit G, Sayre P, Turcanu V, Fisher HR, Broide D, Nirenstein L, Radulovic S, Stephens A, Seyfert-Margolis V, Nasser N, Murphy S, The Immune Tolerance Network ITN032AD Study Group, Lack G Infants with Eczema have High Rates of Sensitization to Food Allergens - Results from the Leap Study. (Abstract #363) 2010 AAAAI Annual Meeting, New Orleans, LA, February 26 - March 2, 2010. [Abstract]
Sagoo P, Hernandez-Fuentes M, Jimenez-Vera E, Rovis F, Hilton R, Warrens A, Lechler RI. Fingerprinting tolerance in Renal Transplantation. (Abstract #A21) 7th Trends in Immunosuppression, Berlin, Germany, February, 2006. [Abstract]
Sagoo P, Hernandez-Fuentes MP, Flavia R, Jimenez E, Perucha E, Stevenson S, Milton R, Warrens A, Lechler RI. Advances in Immune Monitoring in Renal Transplantation. (Abstract #1888) World Transplant Congress, Boston, MA, July 22-27, 2006. [Abstract]
Sagoo P, Sawitzki B, Hernandez-Fuentes MP, Perucha E, Craciun L, Brouard S, Chapman S, Bradeau C, Peters B, Roberts I, Janssen U, Soulillou JP, Warrens AN, Wood K, Goldman M, Volk HD, Lechler RI, www.transplant-tolerance.org.uk/team.aspx, www.transplant-tolerance.org.uk/physicians/. Monitoring peripheral blood regulatory T cells on clinically defined groups of kidney transplant recipients. American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
Sawitzki B, Hernandez-Fuentes MP, Sagoo P, Perucha E, Lemoine A, Brouard S, Chapman S, Peters B, Roberts I, Janssen U, Soulillou JP, Warrens AN, Wood K, Goldman M, Lechler RI, Volk HD. Identification of tolerant patients based on a combinatorial analysis of Foxp3 and aMannosidase transcription. American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
Scheuermann RH, Qian Y, Kong M, Casale TB, Campbell J, Sadat E, Thomson E, Dunn P, Xiang D, Dahlke CE. Automated analysis of flow cytometry data for the identification of cellular markers of allergy therapeutic responses. (Abstract #(J. Immunol., Apr 2010; 184: 91.2)) Immunology 2010 (97th Annual Meeting of the American Association of Immunologists), Baltimore, MD, May 13-17, 2010. [Abstract]
Seyfert VL, Asare AL, Bourcier K, Wang R, Gao Z, Casale TB. Transcriptome Seasonal Regulation in Ragweed Allergy. 2007 AAAAI Annual Meeting, San Diego, CA, Feb 23-27, 2007. [Abstract]
Seyfert-Margolis V. Implication of genomics and proteomics for transplantation (Plenary Lecture). XIX Int'l Congress Transplantation, Miami, FL, Aug 25-30, 2002. [Abstract]
Shaffer J, Kawai T, Cosimi AB, Fudaba Y, Saidman S, Preffer F, Dombkowski D, Delmonico F, McAfee S, Tolkoff-Rubin N, Ballen K, Dey B, Spitzer TR, Sachs DH, Sykes M. Mechanisms of Donor-Specific Unresponsiveness in Tolerant Recipients of Combined Non-Myeloablative HLA-Mismatched Bone Marrow and Kidney Transplantation. (Abstract #O36) 20th International Congress of the Transplantation Society, Vienna, Austria, September 5-10, 2004. [Abstract]
Shaffer JM, Kawai T, Fudaba Y, Cosimi AB, Saidman S, Preffer F, Dombkowski D, Delmonico F, McAfee S, Rubin-Tolkoff N, Dey B, Spitzer TR, Sachs DH, Sykes M. Mechanisms of donor-specific unresponsiveness in tolerant recipient of combined non-myeloablative HLA-mismatched bone marrow and kidney transplantation. (Abstract #526) American Transplant Congress, Boston, MA, May 14-19, 2004. [Abstract]
Shamji M, Wilcock L, Larché M, Durham S and Francis J. Analytical validation of a novel flow cytometric-based Facilitated Allergen Presentation (FAP) assay as a tool for monitoring allergen-specific immunotherapy. 2005 Annual Meeting of the British Society for Allergy & Clinical Immunology, Loughborough, UK, July 18-20, 2005. [Abstract]
Shamji MH, James LK, Francis JN, Kimber I, Till SJ, Durham SR Long-term remission after withdrawal of subcutaneous immunotherapy is associated with persistent elevated serum IgG4-dependent inhibitory activity that is not detectable by measuring serum immunoreactive allergen-specific IgG4 antibody levels. XXVIII Congress of the European Academy of Allergy, Asthma and Immunology (EAACI), Warsaw, Poland, 6-10 June, 2009. [Abstract]
Shamji MH, Wilcock LK, Larche M, Francis JN, Durham SR. Validation of a Functional Assay of IgE-Facilitated CD23-Dependent Allergen Binding to B Cells to Monitor Clinical Efficacy of Immunotherapy. 2006 AAAAI Annual Meeting, Miami, FL, March 3-7, 2006. [Abstract]
Shankar R, Martins SB, O’Connor MJ, Parrish D, and Das AK. Towards semantic interoperability in a clinical trials management system. Fifth International Seman-tic Web Conference (ISWC 2006), Athens, GA, Nov 5-9, 2006. [Abstract]
Shankar R, O'Connor M, Martins S, Tu S, Parrish D, Musen M, Das A. A knowledge-driven approach to manage clinical trial protocols in the Immune Tolerance Network. American Medical Informatics Association Symposium, , October 25, 2005. [Abstract]
Shankar RD, Martins SB, O'Connor MJ, Parrish DB, Das AK A Knowledge-Based System for Managing Clinical Trials. 19th IEEE International Symposium on Computer-Based Medical Systems, Salt Lake City, Utah, June 22-23, 2006. [Abstract]
Shankar RD, Martins SB, O'Connor MJ, Parrish DB, Das AK An Ontology-based Architecture for Integration of Clinical Trials Management Applications. AMIA Annual Symposium, Chicago, IL, Nov 9-15, 2007. [Abstract]
Shankar RD, O'Connor MJ, Parrish DB, Martins SB, Das AK Epoch: an Ontological Framework to Support Clinical Trials Management. International Workshop on Health Information and Knowledge Management (HIKM 2006), Arlington, VA, Nov 11, 2006. [Abstract]
Shapiro AMJ, Ricordi C, Hering B, DiMercurio B, Lindblad R, Alejandro R, Cagliero E, Brendal M, Robertson P, Berney T, Secchi A, Brennan D, Ramos, E, Viviano L, Ryan E, Close N, Lakey J. International Multi-Center Trial of Islet Transplantation Using the Edmonton Protocol in Patients with Type 1 Diabetes. (Abstract #O449) 20th International Congress of the Transplantation Society, Vienna, Austria, September 5-10, 2004. [Abstract]
Shapiro J, Hering B, Ricordi C, Dimercurio B, Lindblad R, Cagliero E, Brendel M, Robertson RP, Berney T, Oberholzer J, Secchi A, Brennan D, Ramos E, Viviano L, Ryan E, Lakey J. International multicenter trial of islet transplantation using the Edmonton protocol in patients with type 1 diabetes. (Abstract #3) American Transplant Congress, Washington, DC, May 30 - Jun 4, 2003. [Abstract]
Shapiro J, Ricordi C, Hering B, Dimercurio B, Lindblad R, Alejandro R, Cagliero E, Brendel M, Robertson P, Berney T, Secchi A, Brennan D, Ramos E, Viviano L, Ryan E, Close N, Lakey J. International multi-center trial of islet transplantation using the Edmonton Protocol in patients with Type 1 diabetes. (Abstract #1904-P) 64th Scientific Sessions of the American Diabetes Association, Orlando, FL, June 4-8, 2004. [Abstract]
Shapiro J, Ricordi C, Hering B, DiMercurio B, Lindblad R, Cagliero E, Brendel M, Robertson P, Berney T, Secchi A, Brennan D, Ramos E, Viviano L, Ryan E, Close N, Lakey J. International multicenter trial of islet transplantation using the Edmonton protocol in patients with type 1 diabetes. . (Abstract #1434) American Transplant Congress, Boston, MA, May 14-19, 2004. [Abstract]
Specks U, Stone JH, ITN RAVE (ITN021AI) Study Group Rituximab for ANCA-associated Vasculitis (RAVE) Trial. 14th Int'l Vasculitis and ANCA Workshop, Lund, Sweden, 6-9 June, 2009. [Abstract]
Spitzer TR, Sykes M, Tolkoff-Rubin N, Kawai T, McAfee SL, Dey BR, Ballen K, Delmonico F, Saidman S, Sachs DA, Cosimi AB Long Term Follow-Up of Recipients of Combined HLA-Matched Nonmyeloablative Bone Marrow and Kidney Transplantation for Multiple Myeloma with End-Stage Renal Disease. American Sociey of Hematology, New Orleans, LA, December 5-8. 2009, 2009. [Abstract]
Srikantha M, Sergeant R, Hernandez-Fuentes M, Lechler RI, Warrens AN. Is it possible to tissue type a kidney donor who is no longer available.. (Abstract #463) American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
Stevenson S, Jiang S, Hernandez-Fuentes M, Lombardi G, Barber L, Lechler RI. Efficacy of Indirect pathway antigen processing and allorecognition. (Abstract #918) 7th Trends in Immunosuppression, Berlin, Germany, February, 2006. [Abstract]
Sykes M. Mixed chimerism: from bench to bedside. (Abstract #0631) XIX Int'l Congress Transplantation, Miami, FL, Aug 25-30, 2002. [Abstract]
Tchao N, Sayre P, Feng S, Fung J, Klintmalm G, Punch J, Trotter C, Ikle D, Shaked A. Long-term immunosuppression management in OLT recipients. American Transplant Congress, San Francisco, CA, May 5-9, 2007. [Abstract]
Vadivel N, Lopez M, Bourcier K, Hill R, Turka LA, Sayegh MH, Najafian N. A novel immune monitoring assay in transplant recipients. (Abstract #783) American Transplant Congress, Toronto, Canada, May 31-Jun 4, 2008. [Abstract]
Vandenbark A, Bartholomew R, Bourdette D. Boosting regulatory T-cells in multiple sclerosis: immunogenicity and safety of a trivalent BV5S2, BV6S5 and BV13S1 CDR2 vaccine in incomplete Freund's adjuvant. 14th Meeting of the European Neurological Society, Barcelona, Spain, June 26-30, 2004. [Abstract]
Vandenbark A, Bartholomew R, Bourdette D. Boosting regulatory T-cells in multiple sclerosis: immunogenicity and safety of a trivalent BV5S2, BV6S5 and BV13S1 CDR2 vaccine in incomplete Freund's adjuvant. II International Congress on Neuroimmunology, Venice, Italy, Sept 28 - Oct 4, 2004. [Abstract]
Vandenbark A, Huan J, Bartholomew R, Offner H, Bourdette D. Decreased Foxp3 levels in MS patients are normalized by TCR peptide vaccination. 19th National Congress of the Polish Neurological Society, Lodz, Poland, Aug 31-Sept 3, 2005. [Abstract]
Vandenbark A, Huan J, Bartholomew R, Offner H, Bourdette D. TCR peptide vaccination in MS induces high levels of IL-10 and restores decreased Foxp3 levels. ECTRIMS/ACTRIMS, Thessaloniki, Greece, Sept 28-Oct 1, 2005. [Abstract]
Vandenbark AA. Treatment of MS patients with TCR peptide vaccine. 4th International Workshop on T-Cell Vaccination, Galillee, Israel, February, 2006. [Abstract]
Waubant E, Pelletier D, Mass M, Cohen J, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi P, Miller A, Mokhtarani M, Iklé D, Ding L, Rosenberg E, ITN020AI Study Management Team, Spencer C, Zamvil SS Atorvastatin therapy in patients with Clinically Isolated Syndrome (CIS): the STAyCIS study. 134th Annual Meeting, American Neurological Assocation, Baltimore, MD, October 11-14, 2009, 2009. [Abstract]
Waubant E, Pelletier D, Mass M, Cohen J, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi P, Miller A, Mokhtarani M, Iklé D, Ding L, Rosenberg E, ITN020AI Study Management Team, Spencer C, Zamvil SS Atorvastatin reduces the risk of new brain MRI lesions in patients with Clinically Isolated Syndrome (CIS) compared to placebo. (Abstract #S21.005) 62nd Annual Meeting of the American Academy of Neurology, Toronto, Canada, April 10-17, 2010. [Abstract]
Wilcock LK, Francis JN, Paraskavopoulos G, Till SJ, Durham SR. Induction of IL-10 Occurs Early and Precedes Serum IgG Blocking Activity During a Cluster Regimen of Grass Pollen Immunotherapy. 2006 AAAAI Annual Meeting, Miami, FL, March 3-7, 2006. [Abstract]
Wilcock LK, Francis JN, Paraskevopolous G, Aalberse RC, Stapel SO, Till SJ and Durham SR. Increased serum inhibitory activity for basophil histamine release corresponds with reductions in early skin responses in a time-course of grass pollen immunotherapy. British Society of Allergy and Clinical Immunology, Loughborough, UK, July, 2006. [Abstract]
Wilcock LK, Wachholz PA, Na D H, Klunker S, Francis JN, Larsen JN, Durham SR. Time-course of serum IgG4 levels and IgG inhibitory activity following withdrawal of grass pollen immunotherapy (IT). J Allergy Clin Immunology, 115, S265, 2005. [Abstract]
Wood K. Towards clinical tolerance: Regulatory mechanisms (Plenary Lecture). XIX Int'l Congress Transplantation, Miami, FL, Aug 25-30, 2002. [Abstract]
Wundes A, Bowen JD, Kraft GH, Hutton GJ, Openshaw H, Forman SJ, Frohman EM, Griffith LM, Muraro PA, Racke MK, Sayre P, Stuve O, Popat U, Nash RA HALT MS - Phase II Clinical Trial of High Dose Immunosuppressive Therapy and Autologous Hematopoietic Stem Cell Transplantation for Active Relapsing-Remitting Multiple Sclerosis. 2009 Annual Meeting of the American Academy of Neurology, Tuczon, AZ, 25-27 June, 2009. [Abstract]
Zhu S, Hu D, Lyu SC, Wong L, Huntsman S, Heinemeyer E, Clayberger C, Bluestone J. T cell activation kinetics from human peripheral blood lymphocytes (PBL) using Affymetrix GeneChip arrays. FOCIS 2003 (Federation of Clinical Immunology Societies), Paris, France, May 15-19, 2003. [Abstract]
Zhu S, Hu D, Wong L, Huntsman S, Heinemeyer E, Bluestone J. Use of a low quantity of RNA for Affymetrix GeneChip arrays. Advanced Microarray Data Analysis, Bethesda, MD, Jan 20, 2003. [Abstract]
Zhu S, Wong L, Hu D, Heinemeyer E, Huntsman S, Boden E, Chikuma S, Ye J, Seyfert-Margolis V, Bluestone JA. Comparison of new standard and amplification procedures with GeneChip arrays for studying T cell activation. (Abstract #471) XXIIth International Congress of Immunology, Montreal, Canada, July 18-23, 2004. [Abstract]