Articles

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Aktas ON, Mateja A, Li MJ, Chatman L, Grieco MC, Baloh CH, Huffaker M, Wheatley LM, du Toit G, Lack G, Brittain E, Frischmeyer-Guerrerio PA (2025). Evaluation of Intestinal Permeability Using Serum Biomarkers in Learning Early About Peanut Allergy Trial. Allergy. https://doi.org/10.1111/all.16464 PMID: 39803811.

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Chandran S, Vincenti F (2025). Antiplasma cell antibodies: A new era of human leukocyte antigen antibody control in solid organ transplantation. Am J Transplant, 25(1), 19-26. https://doi.org/10.1016/j.ajt.2024.10.005 PMID: 39384021.

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Vionnet J, Torres-Yaguana J, Miquel R, Abraldes JG, Wall J, Kodela E, Lozano JJ, Ruiz P, Navasa M, Marshall A, Nevens F, Gelson W, Leithead J, Masson S, Jaeckel E, Taubert R, Tachtatzis P, Eurich D, Simpson KJ, Bonaccorsi-Riani E, Ferguson J, Quaglia A, Demetris AJ, Lesniak AJ, Elstad M, Delord M, Douiri A, Rebollo-Mesa I, Martinez-Llordella M, Silva JAF, Markmann JF, Sánchez-Fueyo A (2024). Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression. Am J Transplant. https://doi.org/10.1016/j.ajt.2024.12.002 PMID: 39706366.

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Tanimine N, Markmann JF, Wood-Trageser MA, Demetris AJ, Mason K, Silva JAF, Levitsky J, Feng S, Humar A, Emond JC, Shaked A, Klintmalm G, Sanchez-Fueyo A, Lesniak D, Breeden CP, Nepom GT, Bridges ND, Goldstein J, Larsen CP, DesMarais M, Gaile G, Chandran S (2024). Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study. Am J Transplant. https://doi.org/10.1016/j.ajt.2024.10.022 PMID: 39505152.

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Baloh CH, Lim N, Huffaker M, Patel P, Tversky J, Du Toit G, Lack G, Laidlaw TM, MacGlashan DW (2024). Peanut-specific IgG subclasses as biomarkers of peanut allergy in LEAP study participants. World Allergy Organ J, 17(8), 100940. https://doi.org/10.1016/j.waojou.2024.100940 PMID: 39247520. PMCID: PMC11380385.

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Özçam M, Lin DL, Gupta CL, Li A, Wheatley LM, Baloh CH, Sanda S, Jones SM, Lynch SV (2024). Enhanced Gut Microbiome Capacity for Amino Acid Metabolism is associated with Peanut Oral Immunotherapy Failure. medRxiv. https://doi.org/10.1101/2024.07.15.24309840 PMID: 39072014. PMCID: PMC11275660.

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Greenbaum CJ, Nepom GT, Wood-Heickman LK, Wherrett DK, DiMeglio LA, Herold KC, Krischer JP (2024). Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop. Diabetes, 73(11), 1780-1790. https://doi.org/10.2337/dbi24-0020 PMID: 39167668. PMCID: PMC11493760.

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Witkop EM, Diggins K, Wiedeman A, Serti E, Nepom G, Gersuk VH, Fuchs B, Long SA, Linsley PS (2024). Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8(+) T cells beneficial in type 1 diabetes. Commun Biol, 7(1), 773. https://doi.org/10.1038/s42003-024-06456-3 PMID: 38937521. PMCID: PMC11211332.

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Foong RX, Du Toit G, van Ree R, Bahnson HT, Radulovic S, Craven J, Kwok M, Jama Z, Versteeg SA, Brough HA, Logan K, Perkin MR, Flohr C, Lack G, Santos AF (2024). Biomarkers of peanut allergy in children over time. Allergy, 79(10), 2775-2786. https://doi.org/10.1111/all.16193 PMID: 38887787.

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Linsley PS, Nakayama M, Balmas E, Chen J, Barahmand-Pour-Whitman F, Bansal S, Bottorff T, Serti E, Speake C, Pugliese A, Cerosaletti K (2024). Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. Nat Commun, 15(1), 4971. https://doi.org/10.1038/s41467-024-48833-w PMID: 38871688. PMCID: PMC11176301.

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Bender C, Wiedeman AE, Hu A, Ylescupidez A, Sietsema WK, Herold KC, Griffin KJ, Gitelman SE, Long SA, T-Rex Study Group†, T-Rex Clinical Study Group (2024). A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes. Sci Transl Med, 16(746), eadn2404. https://doi.org/10.1126/scitranslmed.adn2404 PMID: 38718135.

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Chen CC, Buchheit KM, Lee PY, Brodeur KE, Sohail A, Cho L, Baloh CH, Balestrieri B, Derakhshan T, Feng C, Boyce JA, Dwyer DF, Laidlaw TM (2024). IL-4Rα signaling promotes barrier-altering oncostatin M and IL-6 production in aspirin-exacerbated respiratory disease. J Allergy Clin Immunol, 154(2), 458-467.e3. https://doi.org/10.1016/j.jaci.2024.04.020 PMID: 38704098. PMCID: PMC11305950.

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Higdon LE, Scheiding S, Kus AM, Lim N, Long SA, Anderson MS, Wiedeman AE (2024). Impact on in-depth immunophenotyping of delay to peripheral blood processing. Clin Exp Immunol, 217(2), 119-132. https://doi.org/10.1093/cei/uxae041 PMID: 38693758. PMCID: PMC11239563.

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Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF (2024). Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue. Nat Commun, 15(1), 1564. https://doi.org/10.1038/s41467-024-45012-9 PMID: 38378682. PMCID: PMC10879116.

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Wiley LK, Shortt JA, Roberts ER, Lowery J, Kudron E, Lin M, Mayer D, Wilson M, Brunetti TM, Chavan S, Phang TL, Pozdeyev N, Lesny J, Wicks SJ, Moore ET, Morgenstern JL, Roff AN, Shalowitz EL, Stewart A, Williams C, Edelmann MN, Hull M, Patton JT, Axell L, Ku L, Lee YM, Jirikowic J, Tanaka A, Todd E, White S, Peterson B, Hearst E, Zane R, Greene CS, Mathias R, Coors M, Taylor M, Ghosh D, Kahn MG, Brooks IM, Aquilante CL, Kao D, Rafaels N, Crooks KR, Hess S, Barnes KC, Gignoux CR (2024). Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine. Am J Hum Genet, 111(1), 11-23. https://doi.org/10.1016/j.ajhg.2023.12.001 PMID: 38181729. PMCID: PMC10806731.

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Markmann JF, Burrell BE, Bromberg JS, Hartono C, Kaufman DB, Possselt AM, Naji A, Bridges ND, Breeden C, Kanaparthi S, Pardo J, Kopetskie H, Mason K, Lim N, Chandran S (2024). Immunosuppression withdrawal in living-donor renal transplant recipients following induction with antithymocyte globulin and rituximab: Results of a prospective clinical trial. Am J Transplant, 24(7), 1193-1204. https://doi.org/10.1016/j.ajt.2024.03.007 PMID: 38467375.

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Du Toit G, Huffaker MF, Radulovic S, Feeney M, Fisher HR, Byron M, Dunaway L, Calatroni A, Johnson M, Foong RX, Marques-Mejias A, Bartha I, Basting M, Brough HA, Baloh C, Laidlaw TM, Bahnson HT, Roberts G, Plaut M, Wheatley LM, Lack G, Immune Tolerance Network LEAP-Trio Trial Team (2024). Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention. NEJM Evid, 3(6), EVIDoa2300311. https://doi.org/10.1056/EVIDoa2300311 PMID: 38804779.

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Mathieu C, Wiedeman A, Cerosaletti K, Long SA, Serti E, Cooney L, Vermeiren J, Caluwaerts S, Van Huynegem K, Steidler L, Blomme S, Rottiers P, Nepom GT, Herold KC, AG019-T1D-101 Trial Investigators (2024). A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab. Diabetologia, 67(1), 27-41. https://doi.org/10.1007/s00125-023-06014-2 PMID: 37782353. PMCID: PMC10709251.

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Huffaker MF, Kanchan K, Bahnson HT, Ruczinski I, Shankar G, Leung DYM, Baloh C, Du Toit G, Lack G, Nepom GT, Mathias RA (2023). Epidermal differentiation complex genetic variation in atopic dermatitis and peanut allergy. J Allergy Clin Immunol, 151(4), 1137-1142.e4. https://doi.org/10.1016/j.jaci.2022.11.008 PMID: 36403663.

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Shen Z, Robert L, Stolpman M, Che Y, Allen KJ, Saffery R, Walsh A, Young A, Eckert J, Deming C, Chen Q, Conlan S, Laky K, Li JM, Chatman L, Kashaf SS, NISC Comparative Sequencing Program, VITALITY team, Kong HH, Frischmeyer-Guerrerio PA, Perrett KP, Segre JA (2023). A genome catalog of the early-life human skin microbiome. Genome Biol, 24(1), 252. https://doi.org/10.1186/s13059-023-03090-w PMID: 37946302. PMCID: PMC10636849.

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Azzouz DF, Chen Z, Izmirly PM, Chen LA, Li Z, Zhang C, Mieles D, Trujillo K, Heguy A, Pironti A, Putzel GG, Schwudke D, Fenyo D, Buyon JP, Alekseyenko AV, Gisch N, Silverman GJ (2023). Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares. Ann Rheum Dis, 82(10), 1315-1327. https://doi.org/10.1136/ard-2023-223929 PMID: 37365013. PMCID: PMC10511964.

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Ylescupidez A, Bahnson HT, O'Rourke C, Lord S, Speake C, Greenbaum CJ (2023). A standardized metric to enhance clinical trial design and outcome interpretation in type 1 diabetes. Nat Commun, 14(1), 7214. https://doi.org/10.1038/s41467-023-42581-z PMID: 37940642. PMCID: PMC10632453.

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Taylor PN, Collins KS, Lam A, Karpen SR, Greeno B, Walker F, Lozano A, Atabakhsh E, Ahmed ST, Marinac M, Latres E, Senior PA, Rigby M, Gottlieb PA, Dayan CM, Trial Outcome Markers Initiative collaboration (2023). C-peptide and metabolic outcomes in trials of disease modifying therapy in new-onset type 1 diabetes: an individual participant meta-analysis. Lancet Diabetes Endocrinol, 11(12), 915-925. https://doi.org/10.1016/S2213-8587(23)00267-X PMID: 37931637.

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Cochran W, Salto-Alejandre S, Barker L, Langlee J, Freed K, Carter D, Bannon J, Goddard D, Mostafa H, Werbel W, Shah P, Segev D, Brennan D, Avery R (2023). COVID-19 Outcomes in Solid Organ Transplant Recipients Who Received Tixagevimab-cilgavimab Prophylaxis and/or Bebtelovimab Treatment in a Nurse-driven Monoclonal Antibody Program During the Omicron Surge. Transplantation, 107(2), e60-e61. https://doi.org/10.1097/TP.0000000000004418 PMID: 36228295. PMCID: PMC9875834.

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Delgado AL, Preston-Hurlburt P, Lim N, Sumida TS, Long SA, McNamara J, Serti E, Higdon L, Herold KC (2023). Latent EBV impairs immune cell signaling and enhances the efficacy of anti-CD3 mAb in Type 1 Diabetes. medRxiv. https://doi.org/10.1101/2023.07.11.23292344 PMID: 37502867. PMCID: PMC10370230.

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Calise J, DeBerg H, Garabatos N, Khosa S, Bajzik V, Calderon LB, Aldridge K, Rosasco M, Ferslew BC, Zhu T, Smulders R, Wheatley LM, Laidlaw TM, Qin T, Chichili GR, Adelman DC, Farrington M, Robinson D, Jeong D, Jones SM, Sanda S, Larson D, Kwok WW, Baloh C, Nepom GT, Wambre E, IMPACT (2023). Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy. J Allergy Clin Immunol, 152(1), 155-166.e9. https://doi.org/10.1016/j.jaci.2023.03.020 PMID: 37003475. PMCID: PMC10330178.

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Linsley P, Nakayama M, Balmas E, Chen J, Pour F, Bansal S, Serti E, Speake C, Pugliese A, Cerosaletti K (2023). Self-reactive germline-like TCR alpha chains shared between blood and pancreas. Res Sq. https://doi.org/10.21203/rs.3.rs-3446917/v1 PMID: 37886513. PMCID: PMC10602137.

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Narsale A, Almanza F, Tran T, Lam B, Seo D, Vu A, Long SA, Cooney L, Serti E, Davies JD (2023). Th2 cell clonal expansion at diagnosis in human type 1 diabetes. Clin Immunol, 257, 109829. https://doi.org/10.1016/j.clim.2023.109829 PMID: 37907122.

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Balmas E, Chen J, Hu AK, DeBerg HA, Rosasco MG, Gersuk VH, Serti E, Speake C, Greenbaum CJ, Nepom GT, Linsley PS, Cerosaletti K (2023). Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes. JCI Insight, 8(21). https://doi.org/10.1172/jci.insight.167881 PMID: 37751304. PMCID: PMC10721267.

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Wood-Trageser MA, Lesniak D, Gambella A, Golnoski K, Feng S, Bucuvalas J, Sanchez-Fueyo A, Demetris AJ (2023). Next-generation pathology detection of T cell-antigen-presenting cell immune synapses in human liver allografts. Hepatology, 77(2), 355-366. https://doi.org/10.1002/hep.32666 PMID: 35819312. PMCID: PMC9834436.

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Duan M, Nguyen DC, Joyner CJ, Saney CL, Tipton CM, Andrews J, Lonial S, Kim C, Hentenaar I, Kosters A, Ghosn E, Jackson A, Knechtle S, Maruthamuthu S, Chandran S, Martin T, Rajalingam R, Vincenti F, Breeden C, Sanz I, Gibson G, Lee FE (2023). Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses. Cell Rep, 42(7), 112682. https://doi.org/10.1016/j.celrep.2023.112682 PMID: 37355988. PMCID: PMC10391632.

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Sykes M, Chandran S, Kawai T, Levitsky J, Mapara M, Mathew J, Thomson A, Yamada K (2023). Meeting Report: The Fifth International Samuel Strober Workshop on Clinical Immune Tolerance. Transplantation, 107(3), 564-569. https://doi.org/10.1097/TP.0000000000004473 PMID: 36808845.

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Gamerith G, Mildner F, Merkel PA, Harris K, Cooney L, Lim N, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Fervenza FC, Monach P, Ytterberg SR, Geetha D, Amann A, Wolf D, Specks U, Stone JH, Kronbichler A (2023). Association of baseline soluble immune checkpoints with the risk of relapse in PR3-ANCA vasculitis following induction of remission. Ann Rheum Dis, 82(2), 253-261. https://doi.org/10.1136/ard-2022-222479 PMID: 35973802.

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Russell WE, Bundy BN, Anderson MS, Cooney LA, Gitelman SE, Goland RS, Gottlieb PA, Greenbaum CJ, Haller MJ, Krischer JP, Libman IM, Linsley PS, Long SA, Lord SM, Moore DJ, Moore WV, Moran AM, Muir AB, Raskin P, Skyler JS, Wentworth JM, Wherrett DK, Wilson DM, Ziegler AG, Herold KC, Type 1 Diabetes TrialNet Study Group (2023). Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. Diabetes Care, 46(5), 1005-1013. https://doi.org/10.2337/dc22-2200 PMID: 36920087. PMCID: PMC10154649.

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Odler B, Riedl R, Gauckler P, Shin JI, Leierer J, Merkel PA, St Clair W, Fervenza F, Geetha D, Monach P, Jayne D, Smith RM, Rosenkranz A, Specks U, Stone JH, Kronbichler A, RAVE−ITN Research Group (2023). Risk factors for serious infections in ANCA-associated vasculitis. Ann Rheum Dis, 82(5), 681-687. https://doi.org/10.1136/ard-2022-223401 PMID: 36702528. PMCID: PMC10176387.

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Casal Moura M, Thompson GE, Nelson DR, Fussner LA, Hummel AM, Jenne DE, Emerling D, Fervenza FC, Kallenberg CGM, Langford CA, McCune WJ, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, Stone JH, Robinson WH, Specks U, WGET and RAVE-ITN Research Groups (2023). Activation of a Latent Epitope Causing Differential Binding of Antineutrophil Cytoplasmic Antibodies to Proteinase 3. Arthritis Rheumatol, 75(5), 748-759. https://doi.org/10.1002/art.42418 PMID: 36515151. PMCID: PMC10191989.

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Berti A, Hillion S, Konig MF, Moura MC, Hummel AM, Carmona E, Peikert T, Fervenza FC, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, Brunetta P, St Clair EW, Harris KM, Stone JH, Grandi G, Pers JO, Specks U, Cornec D (2023). Autoreactive Plasmablasts After B Cell Depletion With Rituximab and Relapses in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 75(5), 736-747. https://doi.org/10.1002/art.42388 PMID: 36281741. PMCID: PMC10280646.

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Grinek S, Suprun M, Raghunathan R, Tomalin LE, Getts R, Bahnson T, Lack G, Sampson HA, Suarez-Farinas M (2023). Epitope-Specific IgE at 1 Year of Age Can Predict Peanut Allergy Status at 5 Years. Int Arch Allergy Immunol, 184(3), 273-278. https://doi.org/10.1159/000526364 PMID: 36502801. PMCID: PMC9991938.

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Corren J, Larson D, Altman MC, Segnitz RM, Avila PC, Greenberger PA, Baroody F, Moss MH, Nelson H, Burbank AJ, Hernandez ML, Peden D, Saini S, Tilles S, Hussain I, Whitehouse D, Qin T, Villarreal M, Sever M, Wheatley LM, Nepom GT, Sanda S, Immune Tolerance Network ITN057AD CATNIP Study Team (2023). Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: A randomized controlled trial. J Allergy Clin Immunol, 151(1), 192-201. https://doi.org/10.1016/j.jaci.2022.08.029 PMID: 36223848.

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Altman MC, Segnitz RM, Larson D, Jayavelu ND, Smith MT, Patel S, Scadding GW, Qin T, Sanda S, Steveling E, Eifan AO, Penagos M, Jacobson MR, Parkin RV, Shamji MH, Togias A, Durham SR (2023). Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy. J Allergy Clin Immunol, 152(5), 1247-1260. https://doi.org/10.1016/j.jaci.2023.06.025 PMID: 37460024. PMCID: PMC10788383.

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Logan K, Bahnson HT, Ylescupidez A, Beyer K, Bellach J, Campbell DE, Craven J, Du Toit G, Clare Mills EN, Perkin MR, Roberts G, van Ree R, Lack G (2023). Early introduction of peanut reduces peanut allergy across risk groups in pooled and causal inference analyses. Allergy, 78(5), 1307-1318. https://doi.org/10.1111/all.15597 PMID: 36435990. PMCID: PMC10202125.

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Sever ML, Calatroni A, Roberts G, du Toit G, Bahnson HT, Radulovic S, Larson D, Byron M, Santos AF, Huffaker MF, Wheatley LM, Lack G (2023). Developing a Prediction Model for Determination of Peanut Allergy Status in the Learning Early About Peanut Allergy (LEAP) Studies. J Allergy Clin Immunol Pract, 11(7), 2217-2227.e9. https://doi.org/10.1016/j.jaip.2023.04.032 PMID: 37146884.

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Baloh CH, Kanchan K, Shankar G, Nepom GT, Mathias RA, Perry JA (2023). Omics-oriented research illustrated with the LEAP study and the OASIS bioinformatics tool. J Allergy Clin Immunol, 151(2), 416-419. https://doi.org/10.1016/j.jaci.2022.12.003 PMID: 36521801.

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Suprun M, Bahnson HT, du Toit G, Lack G, Suarez-Farinas M, Sampson HA (2023). In children with eczema, expansion of epitope-specific IgE is associated with peanut allergy at 5 years of age. Allergy, 78(2), 586-589. https://doi.org/10.1111/all.15572 PMID: 36321870.

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Roberts G, Bahnson HT, Du Toit G, O'Rourke C, Sever ML, Brittain E, Plaut M, Lack G (2023). Defining the window of opportunity and target populations to prevent peanut allergy. J Allergy Clin Immunol, 151(5), 1329-1336. https://doi.org/10.1016/j.jaci.2022.09.042 PMID: 36521802. PMCID: PMC10689252.

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Lambert K, Diggins KE, Jones BE, Hundhausen C, Maerz MD, Hocking AM, Sanda S, Greenbaum CJ, Linsley PS, Cerosaletti K, Buckner JH (2022). IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation. Front Immunol, 13, 935394. https://doi.org/10.3389/fimmu.2022.935394 PMID: 35911690. PMCID: PMC9327741.

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Speake C, Habib T, Lambert K, Hundhausen C, Lord S, Dufort MJ, Skinner SO, Hu A, Kinsman M, Jones BE, Maerz MD, Tatum M, Hocking AM, Nepom GT, Greenbaum CJ, Buckner JH (2022). IL-6-targeted therapies to block the cytokine or its receptor drive distinct alterations in T cell function. JCI Insight, 7(22). https://doi.org/10.1172/jci.insight.159436 PMID: 36282595. PMCID: PMC9746808.

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Marwaha AK, Chow S, Pesenacker AM, Cook L, Sun A, Long SA, Yang JHM, Ward-Hartstonge KA, Williams E, Domingo-Vila C, Halani K, Harris KM, Tree TIM, Levings MK, Elliott T, Tan R, Dutz JP (2022). A phase 1b open-label dose-finding study of ustekinumab in young adults with type 1 diabetes. Immunother Adv, 2(1), ltab022. https://doi.org/10.1093/immadv/ltab022 PMID: 35072168. PMCID: PMC8769169.

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Shaked O, Demetris J, Levitsky J, Feng S, Loza BL, Punch J, Reyes J, Klintmalm G, Jackson W, DesMarais M, Sayre P, Shaked A, Reddy KR (2022). Impact of Donor and Recipient Clinical Characteristics and Hepatic Histology on Steatosis/Fibrosis Following Liver Transplantation. Transplantation, 106(1), 106-116. https://doi.org/10.1097/TP.0000000000003681 PMID: 33982909. PMCID: PMC8349377.

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Hübscher SG, Feng S, Gouw ASH, Haga H, Kang HJ, Kelly DA, Komuta M, Lesniak A, Popp BA, Verkade HJ, Yu E, Demetris AJ (2022). Standardizing the histological assessment of late posttransplantation biopsies from pediatric liver allograft recipients. Liver Transpl, 28(9), 1475-1489. https://doi.org/10.1002/lt.26482 PMID: 35429359.

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Perito ER, Persyn E, Bucuvalas J, Martinez M, Mohammad S, Squires JE, Demetris AJ, Feng S (2022). Graft Fibrosis Over 10 to 15 Years in Pediatric Liver Transplant Recipients: Multicenter Study of Paired, Longitudinal Surveillance Biopsies. Liver Transpl, 28(6), 1051-1062. https://doi.org/10.1002/lt.26409 PMID: 35029022.

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Tang Q, Leung J, Peng Y, Sanchez-Fueyo A, Lozano JJ, Lam A, Lee K, Greenland JR, Hellerstein M, Fitch M, Li KW, Esensten JH, Putnam AL, Lares A, Nguyen V, Liu W, Bridges ND, Odim J, Demetris AJ, Levitsky J, Taner T, Feng S (2022). Selective decrease of donor-reactive T(regs) after liver transplantation limits T(reg) therapy for promoting allograft tolerance in humans. Sci Transl Med, 14(669), eabo2628. https://doi.org/10.1126/scitranslmed.abo2628 PMID: 36322627. PMCID: PMC11016119.

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Shimozawa K, Contreras-Ruiz L, Sousa S, Zhang R, Bhatia U, Crisalli KC, Brennan LL, Turka LA, Markmann JF, Guinan EC (2022). Ex vivo generation of regulatory T cells from liver transplant recipients using costimulation blockade. Am J Transplant, 22(2), 504-518. https://doi.org/10.1111/ajt.16842 PMID: 34528383. PMCID: PMC9078620.

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Mexhitaj I, Lim N, Fernandez-Velasco JI, Zrzavy T, Harris KM, Muraro PA, Villar LM, Bar-Or A, Cooney LA (2022). Stabilization of leukocytes from cerebrospinal fluid for central immunophenotypic evaluation in multicenter clinical trials. J Immunol Methods, 510, 113344. https://doi.org/10.1016/j.jim.2022.113344 PMID: 36041516.

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Monach PA, Warner RL, Lew R, Tómasson G, Specks U, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CGM, Langford CA, Seo P, St Clair EW, Spiera R, Johnson KJ, Merkel PA (2022). Serum Biomarkers of Disease Activity in Longitudinal Assessment of Patients with ANCA-Associated Vasculitis. ACR Open Rheumatol, 4(2), 168-176. https://doi.org/10.1002/acr2.11366 PMID: 34792864. PMCID: PMC8843765.

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Smeekens JM, Baloh C, Lim N, Larson D, Qin T, Wheatley L, Kim EH, Jones SM, Burks AW, Kulis MD (2022). Peanut-Specific IgG4 and IgA in Saliva Are Modulated by Peanut Oral Immunotherapy. J Allergy Clin Immunol Pract, 10(12), 3270-3275. https://doi.org/10.1016/j.jaip.2022.07.030 PMID: 35944894. PMCID: PMC9742136.

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Brough HA, Lanser BJ, Sindher SB, Teng JMC, Leung DYM, Venter C, Chan SM, Santos AF, Bahnson HT, Guttman-Yassky E, Gupta RS, Lack G, Ciaccio CE, Sampath V, Nadeau KC, Nagler CR (2022). Early intervention and prevention of allergic diseases. Allergy, 77(2), 416-441. https://doi.org/10.1111/all.15006 PMID: 34255344.

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Review & Commentary

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Rosenberg A, Smilek DE (2024). Editorial: Innovative approaches to immune tolerance and regulation with gene, cellular, protein, and microbiome based therapeutics. Front Immunol, 15, 1382536. https://doi.org/10.3389/fimmu.2024.1382536 PMID: 38482015. PMCID: PMC10933116.

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Russell WE, Moore DJ, Herold KC (2023). Response to Comment on Russell et al. Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. Diabetes Care 2023;46:1005-1013. Diabetes Care, 46(11), e210-e211. https://doi.org/10.2337/dci23-0050 PMID: 37890101. PMCID: PMC10620531.

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Durham SR, Shamji MH (2023). Allergen immunotherapy: past, present and future. Nat Rev Immunol, 23(5), 317-328. https://doi.org/10.1038/s41577-022-00786-1 PMID: 36253555. PMCID: PMC9575636.

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Huffaker MF, Kanchan K, Bahnson HT, Baloh C, Lack G, Nepom GT, Mathias RA (2023). Incorporating genetics in identifying peanut allergy risk and tailoring allergen immunotherapy: A perspective on the genetic findings from the LEAP trial. J Allergy Clin Immunol, 151(4), 841-847. https://doi.org/10.1016/j.jaci.2022.12.819 PMID: 36732171.

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Baloh CH, Mathias RA (2023). Recent progress in the genetic and epigenetic underpinnings of atopy. J Allergy Clin Immunol, 151(1), 60-69. https://doi.org/10.1016/j.jaci.2022.10.027 PMID: 36608983. PMCID: PMC9987265.

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Nepom GT (2022). Synergistic targeting of immunologic pathways to empower durable tolerance therapies. Front Immunol, 13, 962177. https://doi.org/10.3389/fimmu.2022.962177 PMID: 36119087. PMCID: PMC9478166.

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Huffaker MF (2022). The Prevention of Milk Allergy and the Risks of Stopping Too Soon. J Allergy Clin Immunol Pract, 10(1), 180-181. https://doi.org/10.1016/j.jaip.2021.09.011 PMID: 35000732.

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Santos AF, Evans E, O'Rourke C, Bahnson HT, Lack G (2022). Reply to: Life-threatening anaphylaxis to peanut -- impossible to predict? J Allergy Clin Immunol, 149(3), 1129-1131. https://doi.org/10.1016/j.jaci.2021.12.766

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Baloh CH, Huffaker MF, Laidlaw T (2022). Biomarkers and mechanisms of tolerance induction in food allergic patients drive new therapeutic approaches. Front Immunol, 13, 972103. https://doi.org/10.3389/fimmu.2022.972103 PMID: 36263023. PMCID: PMC9574092.

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Podestà MA, Sykes M (2021). Chimerism-Based Tolerance to Kidney Allografts in Humans: Novel Insights and Future Perspectives. Front Immunol, 12, 791725. https://doi.org/10.3389/fimmu.2021.791725 PMID: 35069574. PMCID: PMC8767096.

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Manuscript

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Higdon LE, Cooney, LA, Serti E, Suwannasaen D, Muir VS, Wiedeman AS, Harris, KM, Pardo J, Anderson MS, Speake C, Nepom GT, Linsley PS, Sanda S, Long SA. Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes. J Immunol. Accepted. Manuscript ID: 24-00563-FL

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Van Dooren HJ, van Schaik M, Dorjee AL, Arends AJ, Mackay M, Cooney LA, Fox DA, Wofsy D, Smilek D, Aranow C, Dall'Era M, Huizinga TW J, van Kooten C, Toes RE M, Diamond B, Teng YK O, Suurmond J: Differences in dynamics of specific anti-nuclear antibodies and their susceptibility to B cell targeting treatment in Systemic Lupus Erythematosus. Arthritis and Rheumatology (under review)

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Aranow C, Dall'Era M, Byron M, Ding L, Smilek D, Diamond B, Wofsy D (2018). FRI0305 Phase 2 trial of induction therapy with anti-cd20 (RITUXIMAB) followed by maintenance therapy with anti-baff (BELIMUMAB) in patients with active lupus nephritis. Ann Rheum Dis, 690. https://dx.doi.org/10.1136/annrheumdis-2018-eular.5711

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Specks U, Merkel PA, Hoffman GS, Langford CA, Spiera R, Seo P, Kallenberg CGM, St. Clair EW, Ding L, Webber L, Mokhtarani M, Tchao NK, Sayre PH, Seyfert-Margolis V, Ikle D, Brunetta P, Zhang D, Sejismundo L, Mueller M, Stone JH (2011). Design of the Rituximab in ANCA-associated Vasculitis (RAVE) Trial. The Open Arthritis Journal, 4 (1), 1-18. https://doi.org/10.2174/1876539401104010001

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Vandenbark, A.A., Culbertson, N.E. (2007). Trivalent T Cell Receptor Peptide Vaccine for Treatment of Multiple Sclerosis Targets Predominant V Genes Widely Implicated in Autoimmune Diseases and Allergy. In: Zhang, J. (eds) Immune Regulation and Immunotherapy in Autoimmune Disease. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-36003-4_16

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Commentary

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No items found.

Abstract

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Aranow, C, Diamond, B, Wofsy, D, Byron, M, Smilek, D, Ding, L, Tosta, P, Ryker, K, Gao, W, Dall’Era, M, Features of patients screened for calibrate (rituximab plus cyclophosphamide followed by belimumab for the treatment of lupus nephritis); hypogammaglobulinemia is frequent in patients with marked elevation of urinary protein. https://doi.org/10.1136/lupus-2016-000179.74

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