Study of Tolerant Kidney Transplant Recipients
Principal Investigator
Kenneth Newell | Emory Healthcare | Atlanta, GA
Locations
Emory University | Atlanta,GA
University of Wisconsin | Madison,WI
National Institute of Health | Bethesda,MD
Swedish Medical Center | Seattle,WA
University of Miami | Miami,FL
Study Code
ITN507ST
Study Status
Complete
Abstract
Qualification
Articles
Newell KA, Phippard D, Turka LA (2011). Regulatory cells and cell signatures in clinical transplantation tolerance. Curr Opin Immunol, 23(5), 655-9. https://doi.org/10.1016/j.coi.2011.07.008 PMID: 21982510.
Haynes LD, Jankowska-Gan E, Sheka A, Keller MR, Hernandez-Fuentes MP, Lechler RI, Seyfert-Margolis V, Turka LA, Newell KA, Burlingham WJ (2012). Donor-specific indirect pathway analysis reveals a B-cell-independent signature which reflects outcomes in kidney transplant recipients. Am J Transplant, 12(3), 640-8. https://doi.org/10.1111/j.1600-6143.2011.03869.x PMID: 22151236. PMCID: PMC3374729.
Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Bourcier K, Sharif A, Krajewska M, Lord GM, Roberts I, Goldman M, Wood KJ, Newell K, Seyfert-Margolis V, Warrens AN, Janssen U, Volk HD, Soulillou JP, Hernandez-Fuentes MP, Lechler RI (2010). Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest, 120(6), 1848-61. https://doi.org/10.1172/JCI39922 PMID: 20501943. PMCID: PMC2877932.
Newell KA, Asare A, Kirk AD, Gisler TD, Bourcier K, Suthanthiran M, Burlingham WJ, Marks WH, Sanz I, Lechler RI, Hernandez-Fuentes MP, Turka LA, Seyfert-Margolis VL, Immune Tolerance Network ST507 Study Group (2010). Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest, 120(6), 1836-47. https://doi.org/10.1172/JCI39933 PMID: 20501946. PMCID: PMC2877933.
Srikantha M, Sergeant R, Khan T, Lechler RI, Davey N, Hernandez-Fuentes MP, Warrens AN (2008). Retrospective tissue typing of the kidney donor from recipient urine. Kidney Int, 74(7), 952-5. https://doi.org/10.1038/ki.2008.340 PMID: 18633344.
Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Sachs DH, Cosimi AB, Burlingham WJ, Phippard D, Turka LA (2015). Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients. Am J Transplant, 15(11), 2908-20. https://doi.org/10.1111/ajt.13480 PMID: 26461968. PMCID: PMC4725587.
Danger R, Chesneau M, Paul C, Guérif P, Durand M, Newell KA, Kanaparthi S, Turka LA, Soulillou JP, Houlgatte R, Giral M, Ramstein G, Brouard S (2017). A composite score associated with spontaneous operational tolerance in kidney transplant recipients. Kidney Int, 91(6), 1473-1481. https://doi.org/10.1016/j.kint.2016.12.020 PMID: 28242033. PMCID: PMC5432017.
Asare A, Kanaparthi S, Lim N, Phippard D, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Burrell BE, Morrison Y, Bridges N, Sanz I, Chandraker A, Newell KA, Turka LA (2017). B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function. Am J Transplant, 17(10), 2627-2639. https://doi.org/10.1111/ajt.14283 PMID: 28371372. PMCID: PMC5620117.
Newell KA, Adams AB, Turka LA (2018). Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients. Hum Immunol, 79(5), 380-387. https://doi.org/10.1016/j.humimm.2018.02.007 PMID: 29448053. PMCID: PMC5924709.
