Clinical Trials: The Immune Tolerance Network (ITN) accepts applications for novel clinical trials from all interested scientists from academia, industry and government, in the areas of:

• Allergy & Asthma
• Autoimmune Diseases
• Kidney & Liver Transplantation

Assays & Biomarkers: In addition, the ITN accepts applications for the development of novel tolerance assays or mechanistic studies for the purposes of establishing new surrogate markers of immune tolerance and investigating the mechanisms of clinical tolerance. For example, the ITN will consider proposals that seek to better understand clinical tolerance by utilizing ITN tolerance assay resources in existing or planned clinical trials that are funded through other sources.

The ITN does NOT accept proposals for non-human or preclinical studies.

The Application Process

The ITN application process is a two-stage process designed to fast-track applications from proposal to protocol development. Applicants submit a short (~5-page) Concept Proposal containing a basic outline and justification of the proposed research. Applicants whose proposals are of interest to the ITN will then be asked to submit a more complete Full Application for review.

There is no deadline for submission of Concept Proposals; they are accepted throughout the year with reviews taking place several times per year.

Applicants should note that the ITN review process differs significantly from traditional study section reviews by maintaining a much more interactive method designed to assist potential investigators in the preparation of highly focused, relevant scientific proposals. The number of projects funded and the total available funding varies from year to year.

Complete guidelines and forms are available for download below.
Visit our Submit Proposal page for more details on the proposal submission process.