The ITN conducts clinical trials with the goal of achieving immune tolerance for patients. To see a list of ITN's clinical trials that are currently enrolling participants, please select a disease area:
Below is a list of online resources that will help you decide whether participation in a clinical trial is the right decision for you.
To see all of ITN's active and completed studies, please visit For Researchers.
Principal Investigator:
Doruk Erkan, MD, MPH, Hospital for Special Surgery
Jason Knight, MD, PhD, University of Michigan
A study about the safety of daratumumab in patients with antiphospholipid syndrome (APS), and its effectiveness at reducing the antiphospholipid antibodies that cause APS.
Category:
Allergy & Asthma
Autoimmune Disease
Transplantation
Type 1 Diabetes
|
Transplantation Specific Category:
Learn more:
Principal Investigator:
Brett King, MD, PhD | Yale University
The REVEAL study will investigate whether the experimental study medication, AMG714, can bring back normal color to the skin in vitiligo.
Category:
Allergy & Asthma
Autoimmune Disease
Transplantation
Type 1 Diabetes
|
Transplantation Specific Category:
Learn more:
Principal Investigator:
Patrick Nachman, MD, University of Minnesota
Ignacio Sanz, MD, Emory University
REBOOT will test whether a combination of, belimumab and rituximab, is safe and if this combination is more effective at blocking the immune attack on the kidney of patients with Primary Membranous Neuropathy (MN).
Category:
Allergy & Asthma
Autoimmune Disease
Transplantation
Type 1 Diabetes
|
Transplantation Specific Category:
Learn more:
Principal Investigator:
Jeffrey Cohen, MD, Cleveland Clinic
George Georges, MD, Fred Hutchinson Cancer Research Center
Paolo Muraro, MD, PhD, Imperial College London
BEAT-MS is a clinical trial comparing chemotherapy followed by autologous hematopoietic stem cell transplant (AHSCT) – a type of bone marrow transplantation – to the most effective medicines regularly used to treat relapsing MS.
Category:
Allergy & Asthma
Autoimmune Disease
Transplantation
Type 1 Diabetes
|
Transplantation Specific Category:
Learn more:
Principal Investigator:
Linda DiMeglio, MD, MPH, Indiana University and Riley Hospital for Children, Indianapolis, IN
T1DES is a clinical study for people with type 1 diabetes who were previously enrolled in an ITN clinical study.
Category:
Allergy & Asthma
Autoimmune Disease
Transplantation
Type 1 Diabetes
|
Transplantation Specific Category:
Learn more:
Principal Investigator:
Stuart Knechtle, MD, Duke University Hospital
The goal of the ADAPT study is to study whether using two drugs, carfilzomib and belatacept, together can lower the number of plasma cells in “highly sensitized” people on the kidney transplant waiting list.
Category:
Allergy & Asthma
Autoimmune Disease
Transplantation
Type 1 Diabetes
|
Transplantation Specific Category:
Kidney
Learn more:
Principal Investigator:
Flavio G. Vincenti, MD, University of California, San Francisco Medical Center
The goal of ATTAIN is to study whether using two drugs, daratumumab and belatacept, together can lower the number of plasma cells in “highly sensitized” people on the kidney transplant waiting list.
Category:
Allergy & Asthma
Autoimmune Disease
Transplantation
Type 1 Diabetes
|
Transplantation Specific Category:
Kidney
Learn more:
