The ITN conducts clinical trials with the goal of achieving immune tolerance for patients. To see a list of ITN's clinical trials that are currently enrolling participants, please select a disease area:
Below is a list of online resources that will help you decide whether participation in a clinical trial is the right decision for you.
To see all of ITN's active and completed studies, please visit For Researchers.
Principal Investigator:
Patrick Nachman, MD | University of Minnesota
Ignacio Sanz, MD | Emory University
REBOOT will test whether a combination of, belimumab and rituximab, is safe and if this combination is more effective at blocking the immune attack on the kidney of patients with Primary Membranous Neuropathy (MN).
Category:
Autoimmune Disease
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Specific Category:
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Status:
Active
Learn more:
Principal Investigator:
Jeffrey Cohen, MD | Cleveland Clinic
George Georges, MD | Fred Hutchinson Cancer Research Center
Paolo Muraro, MD, PhD | Imperial College London
BEAT-MS is a clinical trial comparing chemotherapy followed by autologous hematopoietic stem cell transplant (AHSCT) – a type of bone marrow transplantation – to the most effective medicines regularly used to treat relapsing MS.
Category:
Autoimmune Disease
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Specific Category:
Multiple Sclerosis
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Status:
Active
Learn more:
Principal Investigator:
Doruk Erkan, MD, MPH | Hospital for Special Surgery
Jason Knight, MD, PhD | University of Michigan
A study about the safety of daratumumab in patients with antiphospholipid syndrome (APS), and its effectiveness at reducing the antiphospholipid antibodies that cause APS.
Category:
Autoimmune Disease
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Specific Category:
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Status:
Active
Learn more:
Principal Investigator:
Flavio G. Vincenti, MD | University of California, San Francisco Medical Center
The goal of ATTAIN is to study whether using two drugs, daratumumab and belatacept, together can lower the number of plasma cells in “highly sensitized” people on the kidney transplant waiting list.
Category:
Transplantation
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Specific Category:
Kidney Transplantation
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Status:
Active
Learn more:
Principal Investigator:
Stuart Knechtle, MD | Duke University Hospital
The goal of the ADAPT study is to study whether using two drugs, carfilzomib and belatacept, together can lower the number of plasma cells in “highly sensitized” people on the kidney transplant waiting list.
Category:
Transplantation
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Specific Category:
Kidney Transplantation
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Status:
Active
Learn more:
Principal Investigator:
Betty Diamond, MD | Feinstein Institute for Medical Research
David Wofsy, MD | University of California San Francisco School of Medicine
Maria Dall'Era, MD | University of California San Francisco School of Medicine
The goal of the VIBRANT trial is to determine if treating lupus nephritis with VIB4920 in addition to standard therapy is more effective than treating lupus nephritis with standard therapy alone.
Category:
Autoimmune Disease
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Specific Category:
Lupus
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Status:
Active
Learn more:
