Evaluation of Intestinal Permeability Using Serum Biomarkers in Learning Early About Peanut Allergy Trial
Aktas ON, Mateja A, Li MJ, Chatman L, Grieco MC, Baloh CH, Huffaker M, Wheatley LM, du Toit G, Lack G, Brittain E, Frischmeyer-Guerrerio PA
Associated Clinical Trial(s):
Aktas ON, Mateja A, Li MJ, Chatman L, Grieco MC, Baloh CH, Huffaker M, Wheatley LM, du Toit G, Lack G, Brittain E, Frischmeyer-Guerrerio PA (2025). Evaluation of Intestinal Permeability Using Serum Biomarkers in Learning Early About Peanut Allergy Trial. Allergy. https://doi.org/10.1111/all.16464 PMID: 39803811.
Antiplasma cell antibodies: A new era of human leukocyte antigen antibody control in solid organ transplantation
Chandran S, Vincenti F
Associated Clinical Trial(s):
Chandran S, Vincenti F (2025). Antiplasma cell antibodies: A new era of human leukocyte antigen antibody control in solid organ transplantation. Am J Transplant, 25(1), 19-26. https://doi.org/10.1016/j.ajt.2024.10.005 PMID: 39384021.
Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression
Vionnet J, Torres-Yaguana J, Miquel R, Abraldes JG, Wall J, Kodela E, Lozano JJ, Ruiz P, Navasa M, Marshall A, Nevens F, Gelson W, Leithead J, Masson S, Jaeckel E, Taubert R, Tachtatzis P, Eurich D, Simpson KJ, Bonaccorsi-Riani E, Ferguson J, Quaglia A, Demetris AJ, Lesniak AJ, Elstad M, Delord M, Douiri A, Rebollo-Mesa I, Martinez-Llordella M, Silva JAF, Markmann JF, Sánchez-Fueyo A
Associated Clinical Trial(s):
Vionnet J, Torres-Yaguana J, Miquel R, Abraldes JG, Wall J, Kodela E, Lozano JJ, Ruiz P, Navasa M, Marshall A, Nevens F, Gelson W, Leithead J, Masson S, Jaeckel E, Taubert R, Tachtatzis P, Eurich D, Simpson KJ, Bonaccorsi-Riani E, Ferguson J, Quaglia A, Demetris AJ, Lesniak AJ, Elstad M, Delord M, Douiri A, Rebollo-Mesa I, Martinez-Llordella M, Silva JAF, Markmann JF, Sánchez-Fueyo A (2024). Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression. Am J Transplant. https://doi.org/10.1016/j.ajt.2024.12.002 PMID: 39706366.
Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes
Associated Clinical Trial(s):
Higdon LE, Cooney, LA, Serti E, Suwannasaen D, Muir VS, Wiedeman AS, Harris, KM, Pardo J, Anderson MS, Speake C, Nepom GT, Linsley PS, Sanda S, Long SA. Early expansion of TIGIT+PD1+ effector memory CD4 T cells via agonistic effect of alefacept in new-onset type 1 diabetes. J Immunol. Accepted. Manuscript ID: 24-00563-FL
Differences in dynamics of specific anti-nuclear antibodies and their susceptibility to B cell targeting treatment in Systemic Lupus Erythematosus
Associated Clinical Trial(s):
Van Dooren HJ, van Schaik M, Dorjee AL, Arends AJ, Mackay M, Cooney LA, Fox DA, Wofsy D, Smilek D, Aranow C, Dall'Era M, Huizinga TW J, van Kooten C, Toes RE M, Diamond B, Teng YK O, Suurmond J: Differences in dynamics of specific anti-nuclear antibodies and their susceptibility to B cell targeting treatment in Systemic Lupus Erythematosus. Arthritis and Rheumatology (under review)
Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study
Tanimine N, Markmann JF, Wood-Trageser MA, Demetris AJ, Mason K, Silva JAF, Levitsky J, Feng S, Humar A, Emond JC, Shaked A, Klintmalm G, Sanchez-Fueyo A, Lesniak D, Breeden CP, Nepom GT, Bridges ND, Goldstein J, Larsen CP, DesMarais M, Gaile G, Chandran S
Associated Clinical Trial(s):
Tanimine N, Markmann JF, Wood-Trageser MA, Demetris AJ, Mason K, Silva JAF, Levitsky J, Feng S, Humar A, Emond JC, Shaked A, Klintmalm G, Sanchez-Fueyo A, Lesniak D, Breeden CP, Nepom GT, Bridges ND, Goldstein J, Larsen CP, DesMarais M, Gaile G, Chandran S (2024). Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study. Am J Transplant. https://doi.org/10.1016/j.ajt.2024.10.022 PMID: 39505152.
Peanut-specific IgG subclasses as biomarkers of peanut allergy in LEAP study participants
Baloh CH, Lim N, Huffaker M, Patel P, Tversky J, Du Toit G, Lack G, Laidlaw TM, MacGlashan DW
Associated Clinical Trial(s):
Baloh CH, Lim N, Huffaker M, Patel P, Tversky J, Du Toit G, Lack G, Laidlaw TM, MacGlashan DW (2024). Peanut-specific IgG subclasses as biomarkers of peanut allergy in LEAP study participants. World Allergy Organ J, 17(8), 100940. https://doi.org/10.1016/j.waojou.2024.100940 PMID: 39247520. PMCID: PMC11380385.
Enhanced Gut Microbiome Capacity for Amino Acid Metabolism is associated with Peanut Oral Immunotherapy Failure
Özçam M, Lin DL, Gupta CL, Li A, Wheatley LM, Baloh CH, Sanda S, Jones SM, Lynch SV
Associated Clinical Trial(s):
Özçam M, Lin DL, Gupta CL, Li A, Wheatley LM, Baloh CH, Sanda S, Jones SM, Lynch SV (2024). Enhanced Gut Microbiome Capacity for Amino Acid Metabolism is associated with Peanut Oral Immunotherapy Failure. medRxiv. https://doi.org/10.1101/2024.07.15.24309840 PMID: 39072014. PMCID: PMC11275660.
Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop
Greenbaum CJ, Nepom GT, Wood-Heickman LK, Wherrett DK, DiMeglio LA, Herold KC, Krischer JP
Associated Clinical Trial(s):
Greenbaum CJ, Nepom GT, Wood-Heickman LK, Wherrett DK, DiMeglio LA, Herold KC, Krischer JP (2024). Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop. Diabetes, 73(11), 1780-1790. https://doi.org/10.2337/dbi24-0020 PMID: 39167668. PMCID: PMC11493760.
Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8(+) T cells beneficial in type 1 diabetes
Witkop EM, Diggins K, Wiedeman A, Serti E, Nepom G, Gersuk VH, Fuchs B, Long SA, Linsley PS
Associated Clinical Trial(s):
Witkop EM, Diggins K, Wiedeman A, Serti E, Nepom G, Gersuk VH, Fuchs B, Long SA, Linsley PS (2024). Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8(+) T cells beneficial in type 1 diabetes. Commun Biol, 7(1), 773. https://doi.org/10.1038/s42003-024-06456-3 PMID: 38937521. PMCID: PMC11211332.
Biomarkers of peanut allergy in children over time
Foong RX, Du Toit G, van Ree R, Bahnson HT, Radulovic S, Craven J, Kwok M, Jama Z, Versteeg SA, Brough HA, Logan K, Perkin MR, Flohr C, Lack G, Santos AF
Associated Clinical Trial(s):
Foong RX, Du Toit G, van Ree R, Bahnson HT, Radulovic S, Craven J, Kwok M, Jama Z, Versteeg SA, Brough HA, Logan K, Perkin MR, Flohr C, Lack G, Santos AF (2024). Biomarkers of peanut allergy in children over time. Allergy, 79(10), 2775-2786. https://doi.org/10.1111/all.16193 PMID: 38887787.
Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas
Linsley PS, Nakayama M, Balmas E, Chen J, Barahmand-Pour-Whitman F, Bansal S, Bottorff T, Serti E, Speake C, Pugliese A, Cerosaletti K
Associated Clinical Trial(s):
Linsley PS, Nakayama M, Balmas E, Chen J, Barahmand-Pour-Whitman F, Bansal S, Bottorff T, Serti E, Speake C, Pugliese A, Cerosaletti K (2024). Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas. Nat Commun, 15(1), 4971. https://doi.org/10.1038/s41467-024-48833-w PMID: 38871688. PMCID: PMC11176301.
A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes
Bender C, Wiedeman AE, Hu A, Ylescupidez A, Sietsema WK, Herold KC, Griffin KJ, Gitelman SE, Long SA, T-Rex Study Group†, T-Rex Clinical Study Group
Associated Clinical Trial(s):
Bender C, Wiedeman AE, Hu A, Ylescupidez A, Sietsema WK, Herold KC, Griffin KJ, Gitelman SE, Long SA, T-Rex Study Group†, T-Rex Clinical Study Group (2024). A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes. Sci Transl Med, 16(746), eadn2404. https://doi.org/10.1126/scitranslmed.adn2404 PMID: 38718135.
IL-4Rα signaling promotes barrier-altering oncostatin M and IL-6 production in aspirin-exacerbated respiratory disease
Chen CC, Buchheit KM, Lee PY, Brodeur KE, Sohail A, Cho L, Baloh CH, Balestrieri B, Derakhshan T, Feng C, Boyce JA, Dwyer DF, Laidlaw TM
Associated Clinical Trial(s):
Chen CC, Buchheit KM, Lee PY, Brodeur KE, Sohail A, Cho L, Baloh CH, Balestrieri B, Derakhshan T, Feng C, Boyce JA, Dwyer DF, Laidlaw TM (2024). IL-4Rα signaling promotes barrier-altering oncostatin M and IL-6 production in aspirin-exacerbated respiratory disease. J Allergy Clin Immunol, 154(2), 458-467.e3. https://doi.org/10.1016/j.jaci.2024.04.020 PMID: 38704098. PMCID: PMC11305950.
Impact on in-depth immunophenotyping of delay to peripheral blood processing
Higdon LE, Scheiding S, Kus AM, Lim N, Long SA, Anderson MS, Wiedeman AE
Associated Clinical Trial(s):
Higdon LE, Scheiding S, Kus AM, Lim N, Long SA, Anderson MS, Wiedeman AE (2024). Impact on in-depth immunophenotyping of delay to peripheral blood processing. Clin Exp Immunol, 217(2), 119-132. https://doi.org/10.1093/cei/uxae041 PMID: 38693758. PMCID: PMC11239563.
Editorial: Innovative approaches to immune tolerance and regulation with gene, cellular, protein, and microbiome based therapeutics
Rosenberg A, Smilek DE
Associated Clinical Trial(s):
Rosenberg A, Smilek DE (2024). Editorial: Innovative approaches to immune tolerance and regulation with gene, cellular, protein, and microbiome based therapeutics. Front Immunol, 15, 1382536. https://doi.org/10.3389/fimmu.2024.1382536 PMID: 38482015. PMCID: PMC10933116.
Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF
Associated Clinical Trial(s):
Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF (2024). Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue. Nat Commun, 15(1), 1564. https://doi.org/10.1038/s41467-024-45012-9 PMID: 38378682. PMCID: PMC10879116.
Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine
Wiley LK, Shortt JA, Roberts ER, Lowery J, Kudron E, Lin M, Mayer D, Wilson M, Brunetti TM, Chavan S, Phang TL, Pozdeyev N, Lesny J, Wicks SJ, Moore ET, Morgenstern JL, Roff AN, Shalowitz EL, Stewart A, Williams C, Edelmann MN, Hull M, Patton JT, Axell L, Ku L, Lee YM, Jirikowic J, Tanaka A, Todd E, White S, Peterson B, Hearst E, Zane R, Greene CS, Mathias R, Coors M, Taylor M, Ghosh D, Kahn MG, Brooks IM, Aquilante CL, Kao D, Rafaels N, Crooks KR, Hess S, Barnes KC, Gignoux CR
Associated Clinical Trial(s):
Wiley LK, Shortt JA, Roberts ER, Lowery J, Kudron E, Lin M, Mayer D, Wilson M, Brunetti TM, Chavan S, Phang TL, Pozdeyev N, Lesny J, Wicks SJ, Moore ET, Morgenstern JL, Roff AN, Shalowitz EL, Stewart A, Williams C, Edelmann MN, Hull M, Patton JT, Axell L, Ku L, Lee YM, Jirikowic J, Tanaka A, Todd E, White S, Peterson B, Hearst E, Zane R, Greene CS, Mathias R, Coors M, Taylor M, Ghosh D, Kahn MG, Brooks IM, Aquilante CL, Kao D, Rafaels N, Crooks KR, Hess S, Barnes KC, Gignoux CR (2024). Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine. Am J Hum Genet, 111(1), 11-23. https://doi.org/10.1016/j.ajhg.2023.12.001 PMID: 38181729. PMCID: PMC10806731.
Immunosuppression withdrawal in living-donor renal transplant recipients following induction with antithymocyte globulin and rituximab: Results of a prospective clinical trial
Markmann JF, Burrell BE, Bromberg JS, Hartono C, Kaufman DB, Possselt AM, Naji A, Bridges ND, Breeden C, Kanaparthi S, Pardo J, Kopetskie H, Mason K, Lim N, Chandran S
Associated Clinical Trial(s):
Markmann JF, Burrell BE, Bromberg JS, Hartono C, Kaufman DB, Possselt AM, Naji A, Bridges ND, Breeden C, Kanaparthi S, Pardo J, Kopetskie H, Mason K, Lim N, Chandran S (2024). Immunosuppression withdrawal in living-donor renal transplant recipients following induction with antithymocyte globulin and rituximab: Results of a prospective clinical trial. Am J Transplant, 24(7), 1193-1204. https://doi.org/10.1016/j.ajt.2024.03.007 PMID: 38467375.
Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention
Du Toit G, Huffaker MF, Radulovic S, Feeney M, Fisher HR, Byron M, Dunaway L, Calatroni A, Johnson M, Foong RX, Marques-Mejias A, Bartha I, Basting M, Brough HA, Baloh C, Laidlaw TM, Bahnson HT, Roberts G, Plaut M, Wheatley LM, Lack G, Immune Tolerance Network LEAP-Trio Trial Team
Associated Clinical Trial(s):
Du Toit G, Huffaker MF, Radulovic S, Feeney M, Fisher HR, Byron M, Dunaway L, Calatroni A, Johnson M, Foong RX, Marques-Mejias A, Bartha I, Basting M, Brough HA, Baloh C, Laidlaw TM, Bahnson HT, Roberts G, Plaut M, Wheatley LM, Lack G, Immune Tolerance Network LEAP-Trio Trial Team (2024). Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention. NEJM Evid, 3(6), EVIDoa2300311. https://doi.org/10.1056/EVIDoa2300311 PMID: 38804779.
A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab
Mathieu C, Wiedeman A, Cerosaletti K, Long SA, Serti E, Cooney L, Vermeiren J, Caluwaerts S, Van Huynegem K, Steidler L, Blomme S, Rottiers P, Nepom GT, Herold KC, AG019-T1D-101 Trial Investigators
Associated Clinical Trial(s):
Mathieu C, Wiedeman A, Cerosaletti K, Long SA, Serti E, Cooney L, Vermeiren J, Caluwaerts S, Van Huynegem K, Steidler L, Blomme S, Rottiers P, Nepom GT, Herold KC, AG019-T1D-101 Trial Investigators (2024). A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab. Diabetologia, 67(1), 27-41. https://doi.org/10.1007/s00125-023-06014-2 PMID: 37782353. PMCID: PMC10709251.
Epidermal differentiation complex genetic variation in atopic dermatitis and peanut allergy
Huffaker MF, Kanchan K, Bahnson HT, Ruczinski I, Shankar G, Leung DYM, Baloh C, Du Toit G, Lack G, Nepom GT, Mathias RA
Associated Clinical Trial(s):
Huffaker MF, Kanchan K, Bahnson HT, Ruczinski I, Shankar G, Leung DYM, Baloh C, Du Toit G, Lack G, Nepom GT, Mathias RA (2023). Epidermal differentiation complex genetic variation in atopic dermatitis and peanut allergy. J Allergy Clin Immunol, 151(4), 1137-1142.e4. https://doi.org/10.1016/j.jaci.2022.11.008 PMID: 36403663.
A genome catalog of the early-life human skin microbiome
Shen Z, Robert L, Stolpman M, Che Y, Allen KJ, Saffery R, Walsh A, Young A, Eckert J, Deming C, Chen Q, Conlan S, Laky K, Li JM, Chatman L, Kashaf SS, NISC Comparative Sequencing Program, VITALITY team, Kong HH, Frischmeyer-Guerrerio PA, Perrett KP, Segre JA
Associated Clinical Trial(s):
Shen Z, Robert L, Stolpman M, Che Y, Allen KJ, Saffery R, Walsh A, Young A, Eckert J, Deming C, Chen Q, Conlan S, Laky K, Li JM, Chatman L, Kashaf SS, NISC Comparative Sequencing Program, VITALITY team, Kong HH, Frischmeyer-Guerrerio PA, Perrett KP, Segre JA (2023). A genome catalog of the early-life human skin microbiome. Genome Biol, 24(1), 252. https://doi.org/10.1186/s13059-023-03090-w PMID: 37946302. PMCID: PMC10636849.
Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares
Azzouz DF, Chen Z, Izmirly PM, Chen LA, Li Z, Zhang C, Mieles D, Trujillo K, Heguy A, Pironti A, Putzel GG, Schwudke D, Fenyo D, Buyon JP, Alekseyenko AV, Gisch N, Silverman GJ
Associated Clinical Trial(s):
Azzouz DF, Chen Z, Izmirly PM, Chen LA, Li Z, Zhang C, Mieles D, Trujillo K, Heguy A, Pironti A, Putzel GG, Schwudke D, Fenyo D, Buyon JP, Alekseyenko AV, Gisch N, Silverman GJ (2023). Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares. Ann Rheum Dis, 82(10), 1315-1327. https://doi.org/10.1136/ard-2023-223929 PMID: 37365013. PMCID: PMC10511964.
Latent EBV impairs immune cell signaling and enhances the efficacy of anti-CD3 mAb in Type 1 Diabetes
Delgado AL, Preston-Hurlburt P, Lim N, Sumida TS, Long SA, McNamara J, Serti E, Higdon L, Herold KC
Associated Clinical Trial(s):
Delgado AL, Preston-Hurlburt P, Lim N, Sumida TS, Long SA, McNamara J, Serti E, Higdon L, Herold KC (2023). Latent EBV impairs immune cell signaling and enhances the efficacy of anti-CD3 mAb in Type 1 Diabetes. medRxiv. https://doi.org/10.1101/2023.07.11.23292344 PMID: 37502867. PMCID: PMC10370230.
Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy
Calise J, DeBerg H, Garabatos N, Khosa S, Bajzik V, Calderon LB, Aldridge K, Rosasco M, Ferslew BC, Zhu T, Smulders R, Wheatley LM, Laidlaw TM, Qin T, Chichili GR, Adelman DC, Farrington M, Robinson D, Jeong D, Jones SM, Sanda S, Larson D, Kwok WW, Baloh C, Nepom GT, Wambre E, IMPACT
Associated Clinical Trial(s):
Calise J, DeBerg H, Garabatos N, Khosa S, Bajzik V, Calderon LB, Aldridge K, Rosasco M, Ferslew BC, Zhu T, Smulders R, Wheatley LM, Laidlaw TM, Qin T, Chichili GR, Adelman DC, Farrington M, Robinson D, Jeong D, Jones SM, Sanda S, Larson D, Kwok WW, Baloh C, Nepom GT, Wambre E, IMPACT (2023). Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy. J Allergy Clin Immunol, 152(1), 155-166.e9. https://doi.org/10.1016/j.jaci.2023.03.020 PMID: 37003475. PMCID: PMC10330178.
Self-reactive germline-like TCR alpha chains shared between blood and pancreas
Linsley P, Nakayama M, Balmas E, Chen J, Pour F, Bansal S, Serti E, Speake C, Pugliese A, Cerosaletti K
Associated Clinical Trial(s):
Linsley P, Nakayama M, Balmas E, Chen J, Pour F, Bansal S, Serti E, Speake C, Pugliese A, Cerosaletti K (2023). Self-reactive germline-like TCR alpha chains shared between blood and pancreas. Res Sq. https://doi.org/10.21203/rs.3.rs-3446917/v1 PMID: 37886513. PMCID: PMC10602137.
Th2 cell clonal expansion at diagnosis in human type 1 diabetes
Narsale A, Almanza F, Tran T, Lam B, Seo D, Vu A, Long SA, Cooney L, Serti E, Davies JD
Associated Clinical Trial(s):
Narsale A, Almanza F, Tran T, Lam B, Seo D, Vu A, Long SA, Cooney L, Serti E, Davies JD (2023). Th2 cell clonal expansion at diagnosis in human type 1 diabetes. Clin Immunol, 257, 109829. https://doi.org/10.1016/j.clim.2023.109829 PMID: 37907122.
Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes
Balmas E, Chen J, Hu AK, DeBerg HA, Rosasco MG, Gersuk VH, Serti E, Speake C, Greenbaum CJ, Nepom GT, Linsley PS, Cerosaletti K
Associated Clinical Trial(s):
Balmas E, Chen J, Hu AK, DeBerg HA, Rosasco MG, Gersuk VH, Serti E, Speake C, Greenbaum CJ, Nepom GT, Linsley PS, Cerosaletti K (2023). Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes. JCI Insight, 8(21). https://doi.org/10.1172/jci.insight.167881 PMID: 37751304. PMCID: PMC10721267.
Next-generation pathology detection of T cell-antigen-presenting cell immune synapses in human liver allografts
Wood-Trageser MA, Lesniak D, Gambella A, Golnoski K, Feng S, Bucuvalas J, Sanchez-Fueyo A, Demetris AJ
Associated Clinical Trial(s):
Wood-Trageser MA, Lesniak D, Gambella A, Golnoski K, Feng S, Bucuvalas J, Sanchez-Fueyo A, Demetris AJ (2023). Next-generation pathology detection of T cell-antigen-presenting cell immune synapses in human liver allografts. Hepatology, 77(2), 355-366. https://doi.org/10.1002/hep.32666 PMID: 35819312. PMCID: PMC9834436.
