Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients
Newell KA, Turka LA, Adams AB
Newell KA, Turka LA, Adams AB (2018). Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients.. Hum Immunol., 79 (5), 380-387.
Immune monitoring of transplant patients in transient mixed chimerism tolerance trials
Sykes M
Sykes M (2018). Immune monitoring of transplant patients in transient mixed chimerism tolerance trials. Hum Immunol, 79 (5), 334-342.
Alpha‐1 antitrypsin treatment of new‐onset type 1 diabetes: an open‐label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics
Weir GC, Ehlers MR, Harris KM, Kanaparthi S, Long A, Phippard D, Weiner LJ, Jepson B, McNamara JG, Koulmanda M, Strom TB, ITN RETAIN Study Team
Weir GC, Ehlers MR, Harris KM, Kanaparthi S, Long A, Phippard D, Weiner LJ, Jepson B, McNamara JG, Koulmanda M, Strom TB, ITN RETAIN Study Team (2018). Alpha‐1 antitrypsin treatment of new‐onset type 1 diabetes: an open‐label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics. Pediatr Diabetes., E published ahead of print.
Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables
John M. Wentworth, Naiara G. Bediaga, Lynne C. Giles, Mario Ehlers, Stephen E. Gitelman, Susan Geyer, Carmella Evans-Molina, Leonard C. Harrison, the Type 1 Diabetes TrialNet Study Group, the Immune Tolerance Network Study Group
John M. Wentworth, Naiara G. Bediaga, Lynne C. Giles, Mario Ehlers, Stephen E. Gitelman, Susan Geyer, Carmella Evans-Molina, Leonard C. Harrison, the Type 1 Diabetes TrialNet Study Group, the Immune Tolerance Network Study Group (2018). Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables. Diabetologia, Epub ahead of print, 1-8.
Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis
Perdigoto AL, Preston-Hurlburt P, Clark P, Long SA, Linsley PS, Harris KM, Gitelman SE, Greenbaum CJ, Gottlieb PA, Hagopian W, Woodwyk A, Dziura J, Herold K
Perdigoto AL, Preston-Hurlburt P, Clark P, Long SA, Linsley PS, Harris KM, Gitelman SE, Greenbaum CJ, Gottlieb PA, Hagopian W, Woodwyk A, Dziura J, Herold K (2018). Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis.. Diabetologia, Epub ahead of print, 1-10.
Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic Rhinitis: The GRASS Randomized Clinical Trial
Scadding GW, Calderon MA, Shamji MH, Eifan AO, Penagos M, Sever ML, Bahnson HT, Lawson K, Harris KM, Lim N, Tchao NK, Togias A, Dumitru F, Plough AG, Panza JL, Qin T, Durham SR; Immune Tolerance Network GRASS Study Team
Scadding GW, Calderon MA, Shamji MH, Eifan AO, Penagos M, Sever ML, Bahnson HT, Lawson K, Harris KM, Lim N, Tchao NK, Togias A, Dumitru F, Plough AG, Panza JL, Qin T, Durham SR; Immune Tolerance Network GRASS Study Team (2017). Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic Rhinitis: The GRASS Randomized Clinical Trial. JAMA, 317 (6), 615-625.
Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab
Gill MA, Liu AH, Calatroni A, Gern JE, Togias A, Busse WW, Krouse RZ, Shao B, Schiltz A
Gill MA, Liu AH, Calatroni A, Gern JE, Togias A, Busse WW, Krouse RZ, Shao B, Schiltz A (2017). Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab. J Allergy Clin Immunol.
The allergen-specificity of early peanut consumption and the impact on the development of allergic disease in the LEAP Study Cohort
Du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Fisher HR, Feeney M, Radulovic S, Basting M, Plaut M, Lack G; Immune Tolerance Network LEAP Study Team
Du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Fisher HR, Feeney M, Radulovic S, Basting M, Plaut M, Lack G; Immune Tolerance Network LEAP Study Team (2017). The allergen-specificity of early peanut consumption and the impact on the development of allergic disease in the LEAP Study Cohort. J Allergy Clin Immunol, 141 (4), 1343-1353.
LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction
Greenhawt M, Fleischer DM, Chan ES, Venter C, Stukus D, Gupta R, Spergel JM
Greenhawt M, Fleischer DM, Chan ES, Venter C, Stukus D, Gupta R, Spergel JM (2017). LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction. Allergy, 72 (8), 1254-60.
Synchronous Immune Alterations Mirror Clinical Response During Allergen Immunotherapy
Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR, Renand A
Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR, Renand A (2017). Synchronous Immune Alterations Mirror Clinical Response During Allergen Immunotherapy. J Allergy Clin Immunol.
Food Allergy: Update on Prevention and Tolerance
Du Toit G, Plaut M, Lack G, Sampson H, Burks W, Akdis C
Du Toit G, Plaut M, Lack G, Sampson H, Burks W, Akdis C (2017). Food Allergy: Update on Prevention and Tolerance. J Allergy Clin Immunol.
Food Allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention and management
Sicherer SH, Sampson HA
Sicherer SH, Sampson HA (2017). Food Allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention and management. J Allergy Clin Immunol.
Food Allergy: Unmet Needs and New Perspectives
Wang J, Lack G
Wang J, Lack G (2017). Food Allergy: Unmet Needs and New Perspectives. J Allergy Clin Immunol Pract, 5 (2), 295.
Statistical Considerations of Food Allergy Prevention Studies
Bahnson HT, Du Toit G, Lack G
Bahnson HT, Du Toit G, Lack G (2017). Statistical Considerations of Food Allergy Prevention Studies. J Allergy Clin Immunol Pract, 5 (2), 274-82.
Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'
Lawson K, Bahnson HT, Sever M, Du Toit G, Lack G, Brittain E, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J
Lawson K, Bahnson HT, Sever M, Du Toit G, Lack G, Brittain E, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J (2017). Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'. Allergy, 72 (8), 1267-71.
ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis
Khoury SJ, Ding L, Gao W, Arnold DL, Sayre PH, Smilek DE, Rochon J, Byron M, Ryker K, Tosta P, Freedman MS, ACCLAIM Study Group
Khoury SJ, Ding L, Gao W, Arnold DL, Sayre PH, Smilek DE, Rochon J, Byron M, Ryker K, Tosta P, Freedman MS, ACCLAIM Study Group (2017). ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis. Mult Scler.
Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab Determine Body Composition Changes during Induction Treatment of ANCA-Associated Vasculitis
Wallace ZS, Miloslavsky EM, Cascino M, Unizony SH, Lu N, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera R, St Clair EW, Specks U, Brunetta P, Choi HK, Stone JH
Wallace ZS, Miloslavsky EM, Cascino M, Unizony SH, Lu N, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera R, St Clair EW, Specks U, Brunetta P, Choi HK, Stone JH (2017). Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab Determine Body Composition Changes during Induction Treatment of ANCA-Associated Vasculitis. Arthritis Care Res (Hoboken)., 69 (7), 1001-10.
The pharmacogenomic association of Fcγ receptors and cytochrome p450 enzymes and response to treatment with rituximab or cyclophosphamide in Anti-Neutrophil Cytoplasmic Antibody-Associated vasculitis
Cartin-ceba R, Indrakanti D, Specks U, Stone JH, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Spiera RF, Monach PA, Seo P, Tchao NK, Ytterberg SR, St Clair W, Brunetta PG, Song H, Birmingham D, Rovin BH; RAVE-ITN Research Group
Cartin-ceba R, Indrakanti D, Specks U, Stone JH, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Spiera RF, Monach PA, Seo P, Tchao NK, Ytterberg SR, St Clair W, Brunetta PG, Song H, Birmingham D, Rovin BH; RAVE-ITN Research Group (2017). The pharmacogenomic association of Fcγ receptors and cytochrome p450 enzymes and response to treatment with rituximab or cyclophosphamide in Anti-Neutrophil Cytoplasmic Antibody-Associated vasculitis. Arthritis Rheumatol, 69 (1), 169-75.
Association of serum calprotectin (S100A8/S100A9) levels with disease relapses in PR3-ANCA-associated vasculitis
Pepper RJ, Draibe JB, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Monach PA, Seo P, Spiera R, St Clair EW, Tchao NK, Stone JH, Specks U, Merkel PA, Caplin B, Salama AD; RAVE-ITN Research Group
Pepper RJ, Draibe JB, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Monach PA, Seo P, Spiera R, St Clair EW, Tchao NK, Stone JH, Specks U, Merkel PA, Caplin B, Salama AD; RAVE-ITN Research Group (2017). Association of serum calprotectin (S100A8/S100A9) levels with disease relapses in PR3-ANCA-associated vasculitis. Arthritis Rheumatol, 69 (1), 185-93.
Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type
Unizony S, Miloslavsky EM, Lu N, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Ikle D, Tchao NK, Ding L, Brunetta P, Monach PA, Fervenza F, Stone JH, Specks U; RAVE-ITN Research Group, Villarreal M, Kallenberg CM, Choi HK1
Unizony S, Miloslavsky EM, Lu N, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, St Clair EW, Ikle D, Tchao NK, Ding L, Brunetta P, Monach PA, Fervenza F, Stone JH, Specks U; RAVE-ITN Research Group, Villarreal M, Kallenberg CM, Choi HK1 (2017). Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type. Ann Rheum Dis, 75 (6), 1166-9.
High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS
Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Georges GE, Wundes A, Kraft GH, Bowen JD, Steinmiller KC, Wener MH
Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stüve O, Arnold DL, Georges GE, Wundes A, Kraft GH, Bowen JD, Steinmiller KC, Wener MH (2017). High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS. Neurology, Feb 1 2017.
Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis
Clain JM, Hummel AM, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, McCune WJ, Specks U; WGET and RAVE-ITN Research Groups
Clain JM, Hummel AM, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, McCune WJ, Specks U; WGET and RAVE-ITN Research Groups (2017). Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis. Clin Exp Immunol, 188 (1), 174-81.
Correlation of hypogammaglobulinaemia with proteinuria, and the relationship between hypogammaglobulinaemia and infection in active lupus nephritis
N Lim, DE Smilek, L Ding, SG Murray, B Diamond, D Wofsy
N Lim, DE Smilek, L Ding, SG Murray, B Diamond, D Wofsy (2017). Correlation of hypogammaglobulinaemia with proteinuria, and the relationship between hypogammaglobulinaemia and infection in active lupus nephritis. Lupus Sci Med, 4 (1).
Interstitial Immunostaining and Renal Outcomes in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis
Geetha D, Specks U, Kallenberg CGM, Lim N, Spiera R, St Clair EW, Merkel PA, Seo P, Monach PA, Fessler BJ, Langford CA, Hoffman GS, Stone JH, Sethi S, De Vriese AS, Lepori N, Sharma R, Fervenza FC; RAVE-ITN Research Group
Geetha D, Specks U, Kallenberg CGM, Lim N, Spiera R, St Clair EW, Merkel PA, Seo P, Monach PA, Fessler BJ, Langford CA, Hoffman GS, Stone JH, Sethi S, De Vriese AS, Lepori N, Sharma R, Fervenza FC; RAVE-ITN Research Group (2017). Interstitial Immunostaining and Renal Outcomes in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis. Am J Nephrol.
Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis
Merkel PA, Monach PA, Carette S, Cuthbertson D, Hoffman GS, Langford CA, Specks U, Spiera RF, St Clair EW, Stone JH, Ytterberg SR, Xie G, Ji X, Ciavatta DJ, Byun J, Pinder BD, Zhao A, Zhang J, Tadesse Y, Qian D, Weirauch M, Nair R, Tsoi A, Pagnoux C, Chung S, Davis JC Jr, Dellaripa PF, Forbess L, Gewurz-Singer O, Khalidi N, Koening C, Mahr AD, McAlear C, Moreland L, Seo EP, Sreih A, Elder JT, Qu J, Ochi T, Hirano N, Edberg JC, Falk RJ, Amos CI, Siminovitch KA; Vasculitis Clinical Research Consortium
Merkel PA, Monach PA, Carette S, Cuthbertson D, Hoffman GS, Langford CA, Specks U, Spiera RF, St Clair EW, Stone JH, Ytterberg SR, Xie G, Ji X, Ciavatta DJ, Byun J, Pinder BD, Zhao A, Zhang J, Tadesse Y, Qian D, Weirauch M, Nair R, Tsoi A, Pagnoux C, Chung S, Davis JC Jr, Dellaripa PF, Forbess L, Gewurz-Singer O, Khalidi N, Koening C, Mahr AD, McAlear C, Moreland L, Seo EP, Sreih A, Elder JT, Qu J, Ochi T, Hirano N, Edberg JC, Falk RJ, Amos CI, Siminovitch KA; Vasculitis Clinical Research Consortium (2017). Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. Arthritis Rheumatol, 69 (5), 1054-66.
Five year histological and serological follow-up of operationally tolerant pediatric liver transplant recipients enrolled in WISP-R
Feng S, Demetris AJ, Kanaparthi S, Ekong UD, Alonso EM, Rosenthal P, Turka LA, Ikle D, Tchao NK, Spain KM, Burrell BE
Feng S, Demetris AJ, Kanaparthi S, Ekong UD, Alonso EM, Rosenthal P, Turka LA, Ikle D, Tchao NK, Spain KM, Burrell BE (2017). Five year histological and serological follow-up of operationally tolerant pediatric liver transplant recipients enrolled in WISP-R. Hepatology, 65 (2), 647-60.
An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection
Shaked A, Sayre P, Li YR, Asare S, DesMarais M, Holmes MV, Guettouche T, Keating BJ, Chang BL, Barnes MR
Shaked A, Sayre P, Li YR, Asare S, DesMarais M, Holmes MV, Guettouche T, Keating BJ, Chang BL, Barnes MR (2017). An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection. Hepatology, 65 (1), 269-80.
Anti-Gal and anti-Neu5Gc responses in nonimmunosuppressed patients following treatment with rabbit anti-thymocyte polyclonal IgGs
Lim N, Brouard S, Harris KM, Ehlers MR, Gitelman SE, Soulillou JP, Salama A1, Evanno G, Rousse J, Le Berre L, Nicot A
Lim N, Brouard S, Harris KM, Ehlers MR, Gitelman SE, Soulillou JP, Salama A1, Evanno G, Rousse J, Le Berre L, Nicot A (2017). Anti-Gal and anti-Neu5Gc responses in nonimmunosuppressed patients following treatment with rabbit anti-thymocyte polyclonal IgGs. Transplantation, 101 (10), 2501-07.
B Cell Receptor Genes Associated with Tolerance Identify a Cohort of Immunosuppressed Patients with Improved Renal Allograft Graft Function
Asare A, Kanaparthi S, Lim N, Phippard D, Burrell BE, Bridges N, Sanz I, Newell KA, Turka LA, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Morrison Y, Chandraker A
Asare A, Kanaparthi S, Lim N, Phippard D, Burrell BE, Bridges N, Sanz I, Newell KA, Turka LA, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Morrison Y, Chandraker A (2017). B Cell Receptor Genes Associated with Tolerance Identify a Cohort of Immunosuppressed Patients with Improved Renal Allograft Graft Function. Am J Transplant.
Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance
Sprangers B, DeWolf S, Morokata T, LoCascio SA, Shonts B, Zuber J, Morris H, Zorn E, Preffer FI, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M, Savage TM, Obradovic A, Lau SP, Shah R, Steshenko V, Olek S
Sprangers B, DeWolf S, Morokata T, LoCascio SA, Shonts B, Zuber J, Morris H, Zorn E, Preffer FI, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M, Savage TM, Obradovic A, Lau SP, Shah R, Steshenko V, Olek S (2017). Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance. Am J Transplant.
