Food allergy: Update on prevention and tolerance
Du Toit G, Sampson HA, Plaut M, Burks AW, Akdis CA, Lack G
Associated Clinical Trial(s):
Du Toit G, Sampson HA, Plaut M, Burks AW, Akdis CA, Lack G (2018). Food allergy: Update on prevention and tolerance. J Allergy Clin Immunol, 141(1), 30-40. https://doi.org/10.1016/j.jaci.2017.11.010 PMID: 29191680.
Synchronous immune alterations mirror clinical response during allergen immunotherapy
Renand A, Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR
Associated Clinical Trial(s):
Renand A, Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR (2018). Synchronous immune alterations mirror clinical response during allergen immunotherapy. J Allergy Clin Immunol, 141(5), 1750-1760.e1. https://doi.org/10.1016/j.jaci.2017.09.041 PMID: 29128670. PMCID: PMC5938141.
Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort
du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Fisher HR, Feeney M, Radulovic S, Basting M, Plaut M, Lack G, Immune Tolerance Network Learning Early About Peanut Allergy study team
Associated Clinical Trial(s):
du Toit G, Sayre PH, Roberts G, Lawson K, Sever ML, Bahnson HT, Fisher HR, Feeney M, Radulovic S, Basting M, Plaut M, Lack G, Immune Tolerance Network Learning Early About Peanut Allergy study team (2018). Allergen specificity of early peanut consumption and effect on development of allergic disease in the Learning Early About Peanut Allergy study cohort. J Allergy Clin Immunol, 141(4), 1343-1353. https://doi.org/10.1016/j.jaci.2017.09.034 PMID: 29097103. PMCID: PMC5889963.
Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab
Gill MA, Liu AH, Calatroni A, Krouse RZ, Shao B, Schiltz A, Gern JE, Togias A, Busse WW
Associated Clinical Trial(s):
Gill MA, Liu AH, Calatroni A, Krouse RZ, Shao B, Schiltz A, Gern JE, Togias A, Busse WW (2018). Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab. J Allergy Clin Immunol, 141(5), 1735-1743.e9. https://doi.org/10.1016/j.jaci.2017.07.035 PMID: 28870461. PMCID: PMC6013066.
A novel human mast cell activation test for peanut allergy
Santos AF, Couto-Francisco N, Bécares N, Kwok M, Bahnson HT, Lack G
Associated Clinical Trial(s):
Santos AF, Couto-Francisco N, Bécares N, Kwok M, Bahnson HT, Lack G (2018). A novel human mast cell activation test for peanut allergy. J Allergy Clin Immunol, 142(2), 689-691.e9. https://doi.org/10.1016/j.jaci.2018.03.011 PMID: 29731128. PMCID: PMC6080741.
Academic, Foundation, and Industry Collaboration in Finding New Therapies
Ramsey BW, Nepom GT, Lonial S
Associated Clinical Trial(s):
Ramsey BW, Nepom GT, Lonial S (2017). Academic, Foundation, and Industry Collaboration in Finding New Therapies. N Engl J Med, 376(18), 1762-1769. https://doi.org/10.1056/NEJMra1612575 PMID: 28467868. PMCID: PMC5912685.
Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation
Karnell FG, Lin D, Motley S, Duhen T, Lim N, Campbell DJ, Turka LA, Maecker HT, Harris KM
Associated Clinical Trial(s):
Karnell FG, Lin D, Motley S, Duhen T, Lim N, Campbell DJ, Turka LA, Maecker HT, Harris KM (2017). Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation. Clin Exp Immunol, 189(3), 268-278. https://doi.org/10.1111/cei.12985 PMID: 28498568. PMCID: PMC5543487.
Looking behind the data curtain
Nepom GT, Scott D
Associated Clinical Trial(s):
Nepom GT, Scott D (2017). Looking behind the data curtain. Cell Immunol, 319, 1-2. https://doi.org/10.1016/j.cellimm.2017.07.008 PMID: 28754194.
Glycan microarray reveal induced IgGs repertoire shift against a dietary carbohydrate in response to rabbit anti-human thymocyte therapy
Amon R, Ben-Arye SL, Engler L, Yu H, Lim N, Berre LL, Harris KM, Ehlers MR, Gitelman SE, Chen X, Soulillou JP, Padler-Karavani V
Associated Clinical Trial(s):
Amon R, Ben-Arye SL, Engler L, Yu H, Lim N, Berre LL, Harris KM, Ehlers MR, Gitelman SE, Chen X, Soulillou JP, Padler-Karavani V (2017). Glycan microarray reveal induced IgGs repertoire shift against a dietary carbohydrate in response to rabbit anti-human thymocyte therapy. Oncotarget, 8(68), 112236-112244. https://doi.org/10.18632/oncotarget.23096 PMID: 29348821. PMCID: PMC5762506.
Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes
Long SA, Thorpe J, Herold KC, Ehlers M, Sanda S, Lim N, Linsley PS, Nepom GT, Harris KM
Associated Clinical Trial(s):
Long SA, Thorpe J, Herold KC, Ehlers M, Sanda S, Lim N, Linsley PS, Nepom GT, Harris KM (2017). Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes. Cell Immunol, 319, 3-9. https://doi.org/10.1016/j.cellimm.2017.07.007 PMID: 28844471. PMCID: PMC5614459.
Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4(+) T Cells in Peripheral Blood of Subjects with Type 1 Diabetes
Cerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS
Associated Clinical Trial(s):
Cerosaletti K, Barahmand-Pour-Whitman F, Yang J, DeBerg HA, Dufort MJ, Murray SA, Israelsson E, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Wambre E, Prlic M, Gottardo R, Nepom GT, Linsley PS (2017). Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4(+) T Cells in Peripheral Blood of Subjects with Type 1 Diabetes. J Immunol, 199(1), 323-335. https://doi.org/10.4049/jimmunol.1700172 PMID: 28566371. PMCID: PMC5499675.
Mechanisms of Mixed Chimerism-Based Transplant Tolerance
Zuber J, Sykes M
Associated Clinical Trial(s):
Zuber J, Sykes M (2017). Mechanisms of Mixed Chimerism-Based Transplant Tolerance. Trends Immunol, 38(11), 829-843. https://doi.org/10.1016/j.it.2017.07.008 PMID: 28826941. PMCID: PMC5669809.
Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy
Kean LS, Turka LA, Blazar BR
Associated Clinical Trial(s):
Kean LS, Turka LA, Blazar BR (2017). Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunol Rev, 276(1), 192-212. https://doi.org/10.1111/imr.12523 PMID: 28258702. PMCID: PMC5338458.
Dynamics of B Cell Recovery In Kidney/Bone Marrow Transplant Recipients
Gao B, Gu Y, Rong C, Moore C, Porcheray F, Wong W, Preffer F, Saidman SL, Fu Y, Cosimi B, Sachs DH, Kawai T, Sykes M, Zorn E
Associated Clinical Trial(s):
ITN036ST
Mixed Chimerism
,
Gao B, Gu Y, Rong C, Moore C, Porcheray F, Wong W, Preffer F, Saidman SL, Fu Y, Cosimi B, Sachs DH, Kawai T, Sykes M, Zorn E (2017). Dynamics of B Cell Recovery In Kidney/Bone Marrow Transplant Recipients. Transplantation, 101(11), 2722-2730. https://doi.org/10.1097/TP.0000000000001789 PMID: 28422925. PMCID: PMC5648631.
Manufacture of Autologous CD34(+) Selected Grafts in the NIAID-Sponsored HALT-MS and SCOT Multicenter Clinical Trials for Autoimmune Diseases
Keever-Taylor CA, Heimfeld S, Steinmiller KC, Nash RA, Sullivan KM, Czarniecki CW, Granderson TC, Goldstein JS, Griffith LM
Associated Clinical Trial(s):
Keever-Taylor CA, Heimfeld S, Steinmiller KC, Nash RA, Sullivan KM, Czarniecki CW, Granderson TC, Goldstein JS, Griffith LM (2017). Manufacture of Autologous CD34(+) Selected Grafts in the NIAID-Sponsored HALT-MS and SCOT Multicenter Clinical Trials for Autoimmune Diseases. Biol Blood Marrow Transplant, 23(9), 1463-1472. https://doi.org/10.1016/j.bbmt.2017.05.018 PMID: 28602891. PMCID: PMC5761325.
A composite score associated with spontaneous operational tolerance in kidney transplant recipients
Danger R, Chesneau M, Paul C, Guérif P, Durand M, Newell KA, Kanaparthi S, Turka LA, Soulillou JP, Houlgatte R, Giral M, Ramstein G, Brouard S
Associated Clinical Trial(s):
Danger R, Chesneau M, Paul C, Guérif P, Durand M, Newell KA, Kanaparthi S, Turka LA, Soulillou JP, Houlgatte R, Giral M, Ramstein G, Brouard S (2017). A composite score associated with spontaneous operational tolerance in kidney transplant recipients. Kidney Int, 91(6), 1473-1481. https://doi.org/10.1016/j.kint.2016.12.020 PMID: 28242033. PMCID: PMC5432017.
Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance
Sprangers B, DeWolf S, Savage TM, Morokata T, Obradovic A, LoCascio SA, Shonts B, Zuber J, Lau SP, Shah R, Morris H, Steshenko V, Zorn E, Preffer FI, Olek S, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M
Associated Clinical Trial(s):
Sprangers B, DeWolf S, Savage TM, Morokata T, Obradovic A, LoCascio SA, Shonts B, Zuber J, Lau SP, Shah R, Morris H, Steshenko V, Zorn E, Preffer FI, Olek S, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M (2017). Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance. Am J Transplant, 17(8), 2020-2032. https://doi.org/10.1111/ajt.14251 PMID: 28251801. PMCID: PMC5519438.
B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function
Asare A, Kanaparthi S, Lim N, Phippard D, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Burrell BE, Morrison Y, Bridges N, Sanz I, Chandraker A, Newell KA, Turka LA
Associated Clinical Trial(s):
Asare A, Kanaparthi S, Lim N, Phippard D, Vincenti F, Friedewald J, Pavlakis M, Poggio E, Heeger P, Mannon R, Burrell BE, Morrison Y, Bridges N, Sanz I, Chandraker A, Newell KA, Turka LA (2017). B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function. Am J Transplant, 17(10), 2627-2639. https://doi.org/10.1111/ajt.14283 PMID: 28371372. PMCID: PMC5620117.
Anti-Gal and Anti-Neu5Gc Responses in Nonimmunosuppressed Patients After Treatment With Rabbit Antithymocyte Polyclonal IgGs
Salama A, Evanno G, Lim N, Rousse J, Le Berre L, Nicot A, Bach JM, Brouard S, Harris KM, Ehlers MR, Gitelman SE, Soulillou JP
Associated Clinical Trial(s):
Salama A, Evanno G, Lim N, Rousse J, Le Berre L, Nicot A, Bach JM, Brouard S, Harris KM, Ehlers MR, Gitelman SE, Soulillou JP (2017). Anti-Gal and Anti-Neu5Gc Responses in Nonimmunosuppressed Patients After Treatment With Rabbit Antithymocyte Polyclonal IgGs. Transplantation, 101(10), 2501-2507. https://doi.org/10.1097/TP.0000000000001686 PMID: 28198767.
An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection
Shaked A, Chang BL, Barnes MR, Sayre P, Li YR, Asare S, DesMarais M, Holmes MV, Guettouche T, Keating BJ
Associated Clinical Trial(s):
Shaked A, Chang BL, Barnes MR, Sayre P, Li YR, Asare S, DesMarais M, Holmes MV, Guettouche T, Keating BJ (2017). An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection. Hepatology, 65(1), 269-280. https://doi.org/10.1002/hep.28786 PMID: 27533743.
Five-year histological and serological follow-up of operationally tolerant pediatric liver transplant recipients enrolled in WISP-R
Feng S, Demetris AJ, Spain KM, Kanaparthi S, Burrell BE, Ekong UD, Alonso EM, Rosenthal P, Turka LA, Ikle D, Tchao NK
Associated Clinical Trial(s):
Feng S, Demetris AJ, Spain KM, Kanaparthi S, Burrell BE, Ekong UD, Alonso EM, Rosenthal P, Turka LA, Ikle D, Tchao NK (2017). Five-year histological and serological follow-up of operationally tolerant pediatric liver transplant recipients enrolled in WISP-R. Hepatology, 65(2), 647-660. https://doi.org/10.1002/hep.28681 PMID: 27302659. PMCID: PMC5159322.
Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis
Merkel PA, Xie G, Monach PA, Ji X, Ciavatta DJ, Byun J, Pinder BD, Zhao A, Zhang J, Tadesse Y, Qian D, Weirauch M, Nair R, Tsoi A, Pagnoux C, Carette S, Chung S, Cuthbertson D, Davis JC Jr, Dellaripa PF, Forbess L, Gewurz-Singer O, Hoffman GS, Khalidi N, Koening C, Langford CA, Mahr AD, McAlear C, Moreland L, Seo EP, Specks U, Spiera RF, Sreih A, St Clair EW, Stone JH, Ytterberg SR, Elder JT, Qu J, Ochi T, Hirano N, Edberg JC, Falk RJ, Amos CI, Siminovitch KA, Vasculitis Clinical Research Consortium
Associated Clinical Trial(s):
Merkel PA, Xie G, Monach PA, Ji X, Ciavatta DJ, Byun J, Pinder BD, Zhao A, Zhang J, Tadesse Y, Qian D, Weirauch M, Nair R, Tsoi A, Pagnoux C, Carette S, Chung S, Cuthbertson D, Davis JC Jr, Dellaripa PF, Forbess L, Gewurz-Singer O, Hoffman GS, Khalidi N, Koening C, Langford CA, Mahr AD, McAlear C, Moreland L, Seo EP, Specks U, Spiera RF, Sreih A, St Clair EW, Stone JH, Ytterberg SR, Elder JT, Qu J, Ochi T, Hirano N, Edberg JC, Falk RJ, Amos CI, Siminovitch KA, Vasculitis Clinical Research Consortium (2017). Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. Arthritis Rheumatol, 69(5), 1054-1066. https://doi.org/10.1002/art.40034 PMID: 28029757. PMCID: PMC5434905.
Interstitial Immunostaining and Renal Outcomes in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis
Geetha D, Sethi S, De Vriese AS, Specks U, Kallenberg CGM, Lim N, Spiera R, St Clair EW, Merkel PA, Seo P, Monach PA, Lepori N, Fessler BJ, Langford CA, Hoffman GS, Sharma R, Stone JH, Fervenza FC, RAVE-ITN Research Group
Associated Clinical Trial(s):
Geetha D, Sethi S, De Vriese AS, Specks U, Kallenberg CGM, Lim N, Spiera R, St Clair EW, Merkel PA, Seo P, Monach PA, Lepori N, Fessler BJ, Langford CA, Hoffman GS, Sharma R, Stone JH, Fervenza FC, RAVE-ITN Research Group (2017). Interstitial Immunostaining and Renal Outcomes in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis. Am J Nephrol, 46(3), 231-238. https://doi.org/10.1159/000480443 PMID: 28881339. PMCID: PMC6640633.
Correlation of hypogammaglobulinaemia with proteinuria, and the relationship between hypogammaglobulinaemia and infection in active lupus nephritis
Smilek DE, Lim N, Ding L, Murray SG, Diamond B, Wofsy D
Associated Clinical Trial(s):
Smilek DE, Lim N, Ding L, Murray SG, Diamond B, Wofsy D (2017). Correlation of hypogammaglobulinaemia with proteinuria, and the relationship between hypogammaglobulinaemia and infection in active lupus nephritis. Lupus Sci Med, 4(1), e000229. https://doi.org/10.1136/lupus-2017-000229 PMID: 29214037. PMCID: PMC5704742.
Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis
Clain JM, Hummel AM, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, McCune WJ, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, Specks U, WGET and RAVE-ITN Research Groups
Associated Clinical Trial(s):
Clain JM, Hummel AM, Stone JH, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, McCune WJ, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Ytterberg SR, Specks U, WGET and RAVE-ITN Research Groups (2017). Immunoglobulin (Ig)M antibodies to proteinase 3 in granulomatosis with polyangiitis and microscopic polyangiitis. Clin Exp Immunol, 188(1), 174-181. https://doi.org/10.1111/cei.12925 PMID: 28076879. PMCID: PMC5343341.
High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS
Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Steinmiller KC, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stuve O, Arnold DL, Wener MH, Georges GE, Wundes A, Kraft GH, Bowen JD
Associated Clinical Trial(s):
Nash RA, Hutton GJ, Racke MK, Popat U, Devine SM, Steinmiller KC, Griffith LM, Muraro PA, Openshaw H, Sayre PH, Stuve O, Arnold DL, Wener MH, Georges GE, Wundes A, Kraft GH, Bowen JD (2017). High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS. Neurology, 88(9), 842-852. https://doi.org/10.1212/WNL.0000000000003660 PMID: 28148635. PMCID: PMC5331868.
Association of Serum Calprotectin (S100A8/A9) Level With Disease Relapse in Proteinase 3-Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Pepper RJ, Draibe JB, Caplin B, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Monach PA, Seo P, Spiera R, William St Clair E, Tchao NK, Stone JH, Specks U, Merkel PA, Salama AD, RAVE-Immune Tolerance Network Research Group
Associated Clinical Trial(s):
Pepper RJ, Draibe JB, Caplin B, Fervenza FC, Hoffman GS, Kallenberg CG, Langford CA, Monach PA, Seo P, Spiera R, William St Clair E, Tchao NK, Stone JH, Specks U, Merkel PA, Salama AD, RAVE-Immune Tolerance Network Research Group (2017). Association of Serum Calprotectin (S100A8/A9) Level With Disease Relapse in Proteinase 3-Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 69(1), 185-193. https://doi.org/10.1002/art.39814 PMID: 27428710. PMCID: PMC5839649.
The Pharmacogenomic Association of Fcγ Receptors and Cytochrome P450 Enzymes With Response to Rituximab or Cyclophosphamide Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Cartin-Ceba R, Indrakanti D, Specks U, Stone JH, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Spiera RF, Monach PA, St Clair EW, Seo P, Tchao NK, Ytterberg SR, Brunetta PG, Song H, Birmingham D, Rovin BH, RAVE-Immune Tolerance Network Research Group
Associated Clinical Trial(s):
Cartin-Ceba R, Indrakanti D, Specks U, Stone JH, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Spiera RF, Monach PA, St Clair EW, Seo P, Tchao NK, Ytterberg SR, Brunetta PG, Song H, Birmingham D, Rovin BH, RAVE-Immune Tolerance Network Research Group (2017). The Pharmacogenomic Association of Fcγ Receptors and Cytochrome P450 Enzymes With Response to Rituximab or Cyclophosphamide Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 69(1), 169-175. https://doi.org/10.1002/art.39822 PMID: 27482943.
Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab on Body Composition During Induction Treatment of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Wallace ZS, Miloslavsky EM, Cascino M, Unizony SH, Lu N, Hoffman GS, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera R, St Clair EW, Specks U, Brunetta P, Choi HK, Stone JH
Associated Clinical Trial(s):
Wallace ZS, Miloslavsky EM, Cascino M, Unizony SH, Lu N, Hoffman GS, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera R, St Clair EW, Specks U, Brunetta P, Choi HK, Stone JH (2017). Effect of Disease Activity, Glucocorticoid Exposure, and Rituximab on Body Composition During Induction Treatment of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Care Res (Hoboken), 69(7), 1004-1010. https://doi.org/10.1002/acr.23099 PMID: 27696762. PMCID: PMC5611860.
ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis
Khoury SJ, Rochon J, Ding L, Byron M, Ryker K, Tosta P, Gao W, Freedman MS, Arnold DL, Sayre PH, Smilek DE, ACCLAIM Study Group
Associated Clinical Trial(s):
Khoury SJ, Rochon J, Ding L, Byron M, Ryker K, Tosta P, Gao W, Freedman MS, Arnold DL, Sayre PH, Smilek DE, ACCLAIM Study Group (2017). ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis. Mult Scler, 23(5), 686-695. https://doi.org/10.1177/1352458516662727 PMID: 27481207. PMCID: PMC5288398.
