A composite score associated with spontaneous operational tolerance in kidney transplant recipients
Danger R, Chesneau M, Paul C, Guérif P, Durand M, Newell KA, Kanaparthi S, Turka LA, Soulillou JP, Houlgatte R, Giral M, Ramstein G, Brouard S
Danger R, Chesneau M, Paul C, Guérif P, Durand M, Newell KA, Kanaparthi S, Turka LA, Soulillou JP, Houlgatte R, Giral M, Ramstein G, Brouard S (2017). A composite score associated with spontaneous operational tolerance in kidney transplant recipients. Kidney Int, 91 (1), 1473-81.
Manufacture of Autologous CD34+ Selected Grafts in the NIAID-Sponsored HALT-MS and SCOT Multicenter Clinical Trials for Autoimmune Diseases
Keever-Taylor CA, Heimfeld S, Steinmiller KC, Nash RA, Sullivan KM, Czarniecki CW, Granderson TC, Goldstein JS, Griffith LM
Keever-Taylor CA, Heimfeld S, Steinmiller KC, Nash RA, Sullivan KM, Czarniecki CW, Granderson TC, Goldstein JS, Griffith LM (2017). Manufacture of Autologous CD34+ Selected Grafts in the NIAID-Sponsored HALT-MS and SCOT Multicenter Clinical Trials for Autoimmune Diseases. Biol Blood Marrow Transplant, 23 (9), 1463-1472.
Dynamics of B Cell Recovery In Kidney/Bone Marrow Transplant Recipients
Gao B1, Gu Y, Rong C, Moore C, Porcheray F, Wong W, Preffer F, Saidman Sl, Fu Y, Cosimi B, Sachs DH, Kawai T, Sykes M, Zorn E
Gao B1, Gu Y, Rong C, Moore C, Porcheray F, Wong W, Preffer F, Saidman Sl, Fu Y, Cosimi B, Sachs DH, Kawai T, Sykes M, Zorn E (2017). Dynamics of B Cell Recovery In Kidney/Bone Marrow Transplant Recipients. Transplantation, 101 (11), 2722-2730.
Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy
Kean LS, Turka LA, Blazar BR
Kean LS, Turka LA, Blazar BR (2017). Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy. Immunol Rev, 276 (1), 192-212.
Mechanisms of Mixed Chimerism-Based Transplant Tolerance
Zuber J, Sykes M
Zuber J, Sykes M (2017). Mechanisms of Mixed Chimerism-Based Transplant Tolerance. Trends Immunol., 38 (11), 829-43.
Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes
Yang J, DeBerg HA, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Gottardo R, Nepom GT, Linsley PS, Cerosaletti K, Barahmand-Pour-Whitman F, Dufort MJ, Murray SA, Israelsson E, Wambre E, Prlic M
Yang J, DeBerg HA, Speake C, Gersuk VH, Eddy JA, Reijonen H, Greenbaum CJ, Kwok WW, Gottardo R, Nepom GT, Linsley PS, Cerosaletti K, Barahmand-Pour-Whitman F, Dufort MJ, Murray SA, Israelsson E, Wambre E, Prlic M (2017). Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes. J Immunol, 199 (1), 323-35.
Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 Diabetes
A Long, J Thorpe, KC Herold, M Ehlers, S Sanda, N Lim, PS Linsley, GT Nepom, KM Harris
A Long, J Thorpe, KC Herold, M Ehlers, S Sanda, N Lim, PS Linsley, GT Nepom, KM Harris (2017). Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 Diabetes. Cell Immunol.
Glycan microarray reveal induced IgGs repertoire shift against a dietary carbohydrate in response to rabbit anti-human thymocyte therapy
Amon R, Ben-Arye SL, Engler L, Yu H, Lim N, Berre LL, Harris KM, Ehlers MR, Gitelman SE, Chen X, Soulillou JP, Padler-Karavani V
Amon R, Ben-Arye SL, Engler L, Yu H, Lim N, Berre LL, Harris KM, Ehlers MR, Gitelman SE, Chen X, Soulillou JP, Padler-Karavani V (2017). Glycan microarray reveal induced IgGs repertoire shift against a dietary carbohydrate in response to rabbit anti-human thymocyte therapy. Oncotarget, 8 (68), 112236-112244.
Looking behind the data curtain
Nepom GT, Scott D
Nepom GT, Scott D (2017). Looking behind the data curtain. Cell Immunol.
Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation
Karnell FG, Lin D, Motley S, Duhen T, Lim N, Campbell DJ, Turka LA, Maecker HT, Harris KM
Karnell FG, Lin D, Motley S, Duhen T, Lim N, Campbell DJ, Turka LA, Maecker HT, Harris KM (2017). Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation. Clin Exp Immunol, 189 (3), 268-78.
Effect of Avoidance on Peanut Allergy after Early Peanut Consumption
Du Toit G, Sayre PH, Roberts G, Sever ML, Lawson K, Bahnson HT, Brough HA, Santos AF, Harris KM, Radulovic S, Basting M, Turcanu V, Plaut M, Lack G; Immune Tolerance Network LEAP-On Study Team
Du Toit G, Sayre PH, Roberts G, Sever ML, Lawson K, Bahnson HT, Brough HA, Santos AF, Harris KM, Radulovic S, Basting M, Turcanu V, Plaut M, Lack G; Immune Tolerance Network LEAP-On Study Team (2016). Effect of Avoidance on Peanut Allergy after Early Peanut Consumption. N Engl J Med, 14 (374), 1435-43.
Impact of peanut consumption in the LEAP Study: Feasibility, growth, and nutrition
Feeney M, Du Toit G, Roberts G, Sayre PH, Lawson K, Bahnson HT, Sever ML, Radulovic S, Plaut M, Lack G, Immune Tolerance Network LEAP Study Team
Feeney M, Du Toit G, Roberts G, Sayre PH, Lawson K, Bahnson HT, Sever ML, Radulovic S, Plaut M, Lack G, Immune Tolerance Network LEAP Study Team (2016). Impact of peanut consumption in the LEAP Study: Feasibility, growth, and nutrition . J Allergy Clin Immunol, pii: S0091-6749 (16), 30262-7.
Prevention of food allergy
Du Toit G, Lack G, Tsakok T, Lack S
Du Toit G, Lack G, Tsakok T, Lack S (2016). Prevention of food allergy. J Allergy Clin Immunol, 137 (4), 998-1010.
Vitamin D in clinically isolated syndrome: evidence for possible neuroprotection
Pelletier D, Gao Z, Zamvil SS, Waubant E, Mowry EM, Howell MD
Pelletier D, Gao Z, Zamvil SS, Waubant E, Mowry EM, Howell MD (2016). Vitamin D in clinically isolated syndrome: evidence for possible neuroprotection. Eur J Neurol, 23 (2), 327-32.
Factors Determining the Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3
Hummel AM, Cartin-ceba R, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Tchao NK, Stone JH, Fussner LA, Schroeder DR, Silva F, Snyder MR, Specks U; RAVE-ITN Research Group.
Hummel AM, Cartin-ceba R, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Tchao NK, Stone JH, Fussner LA, Schroeder DR, Silva F, Snyder MR, Specks U; RAVE-ITN Research Group. (2016). Factors Determining the Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3. Arthritis Rheumatol, 68 (7), 1700-10.
International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials
Galipeau J, Krampera M, Barrett J, Dazzi F, Deans RJ, DeBruijn J, Dominici M, Fibbe WE, Gee AP, Gimble JM, Hematti P, Koh MB, LeBlanc K, Martin I, McNiece IK, Mendicino M, Oh S, Ortiz L, Phinney DG, Planat V, Shi Y, Stroncek DF, Viswanathan S, Weiss DJ, Sensebe L
Galipeau J, Krampera M, Barrett J, Dazzi F, Deans RJ, DeBruijn J, Dominici M, Fibbe WE, Gee AP, Gimble JM, Hematti P, Koh MB, LeBlanc K, Martin I, McNiece IK, Mendicino M, Oh S, Ortiz L, Phinney DG, Planat V, Shi Y, Stroncek DF, Viswanathan S, Weiss DJ, Sensebe L (2016). International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials. Cytotherapy, 18 (2), 151-9.
A role for plasma cell targeting agents in immune tolerance induction in autoimmune disease and antibody responses to therapeutic proteins
Diamond B, Turka LA, Rosenberg AS, Pariser AR, Yao L, Lacana E, Kishnani PS
Diamond B, Turka LA, Rosenberg AS, Pariser AR, Yao L, Lacana E, Kishnani PS (2016). A role for plasma cell targeting agents in immune tolerance induction in autoimmune disease and antibody responses to therapeutic proteins. Clin Immunol, 165 (April 2016), 55-9.
Myeloperoxidase-Antineutrophil Cytoplasmic Antibody (ANCA)-Positive and ANCA-Negative Patients With Granulomatosis With Polyangiitis (Wegener's): Distinct Patient Subsets
Miloslavsky EM, Lu N, Unizony S, Choi HK, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Fervenza F, Monach PA, Specks U, Stone JH
Miloslavsky EM, Lu N, Unizony S, Choi HK, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Fervenza F, Monach PA, Specks U, Stone JH (2016). Myeloperoxidase-Antineutrophil Cytoplasmic Antibody (ANCA)-Positive and ANCA-Negative Patients With Granulomatosis With Polyangiitis (Wegener's): Distinct Patient Subsets. Arthritis Rheumatol, 68 (12), 2945-52.
Long-Term Follow-Up of the Edmonton Protocol of Islet Transplantation in the United States
Brennan DC, Kopetskie HA, Sayre PH, Alejandro R, Cagliero E, Shapiro AM, Goldstein JS, DesMarais MR, Booher S, Bianchine PJ
Brennan DC, Kopetskie HA, Sayre PH, Alejandro R, Cagliero E, Shapiro AM, Goldstein JS, DesMarais MR, Booher S, Bianchine PJ (2016). Long-Term Follow-Up of the Edmonton Protocol of Islet Transplantation in the United States. Am J Transplant, 16 (2), 509-17.
Changes in T-cell subsets identify responders to FcR non-binding anti-CD3 mAb (teplizumab) in patients with Type 1 diabetes
Tooley JE, Vudattu N, Choi J, Cotsapas C, Devine L, Raddassi K, Ehlers MR, Harris KM, Kanaparthi S, Phippard D, Herold KC, McNamara JG
Tooley JE, Vudattu N, Choi J, Cotsapas C, Devine L, Raddassi K, Ehlers MR, Harris KM, Kanaparthi S, Phippard D, Herold KC, McNamara JG (2016). Changes in T-cell subsets identify responders to FcR non-binding anti-CD3 mAb (teplizumab) in patients with Type 1 diabetes. Eur J Immunol, 46 (1), 230-41.
A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice
Gill RG, Pagni PP, Posgai A, Manenkova Y, Straub L, Bernstein P, Herold KC, von Herrath M, Staeva T, Ehlers MR, Nepom GT, Kufper T, Wasserfall CH, Deng S, Hani AB, Atkinson MA
Gill RG, Pagni PP, Posgai A, Manenkova Y, Straub L, Bernstein P, Herold KC, von Herrath M, Staeva T, Ehlers MR, Nepom GT, Kufper T, Wasserfall CH, Deng S, Hani AB, Atkinson MA (2016). A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice. Diabetes, 65 (5), 1310-16.
Two- and Four-Hour Tests Differ in Capture of C-Peptide Responses to a Mixed Meal in Type 1 Diabetes
Boyle KD, Keyes-Elstein L, Ehlers MR, McNamara J, Rigby MR, Gitelman SE, Herold KC, Weiner LJ, Much KL
Boyle KD, Keyes-Elstein L, Ehlers MR, McNamara J, Rigby MR, Gitelman SE, Herold KC, Weiner LJ, Much KL (2016). Two- and Four-Hour Tests Differ in Capture of C-Peptide Responses to a Mixed Meal in Type 1 Diabetes. Diabetes Care, 39 (6), e76-8.
Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2 year results of a randomised trial
Gitelman SE, Gottlieb PA, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Harris KM, Kanaparthi S, Phippard D, Ding L, Bluestone JA, Ehlers MR; ITN START Study Team
Gitelman SE, Gottlieb PA, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Harris KM, Kanaparthi S, Phippard D, Ding L, Bluestone JA, Ehlers MR; ITN START Study Team (2016). Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2 year results of a randomised trial. Diabetologia, 59 (6), 1153-61.
Correlation Among Hypoglycemia, Glycemic Variability, and C-Peptide Preservation After Alefacept Therapy in Patients with Type 1 Diabetes Mellitus: Analysis of Data from the Immune Tolerance Network T1DAL Trial
Pinckney A, Rigby MR, Keyes-Elstein L, Soppe CL, Nepom GT, Ehlers MR
Pinckney A, Rigby MR, Keyes-Elstein L, Soppe CL, Nepom GT, Ehlers MR (2016). Correlation Among Hypoglycemia, Glycemic Variability, and C-Peptide Preservation After Alefacept Therapy in Patients with Type 1 Diabetes Mellitus: Analysis of Data from the Immune Tolerance Network T1DAL Trial. Clin Ther, 38 (6), 1327-39.
Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes
Long SA, Harris KM, Ehlers M, Herold KC, Nepom GT, Jerill Thorpe J, DeBerg HA, Gersuk V, Eddy JA, Linsley PS
Long SA, Harris KM, Ehlers M, Herold KC, Nepom GT, Jerill Thorpe J, DeBerg HA, Gersuk V, Eddy JA, Linsley PS (2016). Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes. Science Immunology, 1 (5), pii: eaai7793.
Immune Interventions to Preserve β Cell Function in Type 1 Diabetes
Ehlers MR
Ehlers MR (2016). Immune Interventions to Preserve β Cell Function in Type 1 Diabetes. J Investig Med, 64 (1), 7-13.
Strategies for clinical trials in type 1 diabetes
Ehlers MR
Ehlers MR (2016). Strategies for clinical trials in type 1 diabetes. J Autoimmun, Jul (71), 88-96.
Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes
Buckner JH, Nepom GT
Buckner JH, Nepom GT (2016). Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes. J Autoimmun, Jul (71), 44-50.
Clinical trial data access: Opening doors with TrialShare
Asare AL, Carey VJ, Rotrosen D, Nepom GT
Asare AL, Carey VJ, Rotrosen D, Nepom GT (2016). Clinical trial data access: Opening doors with TrialShare. J Allergy Clin Immunol.
Randomized trial of peanut consumption in infants at risk for peanut allergy
Du Toit G, Roberts G, Sayre PH, Bahnson HT, Radulovic S, Santos AF, Brough HA, Phippard D, Basting M, Feeney M, Turcanu V, Sever ML, Gomez Lorenzo M, Plaut M, Lack G; LEAP Study Team
Du Toit G, Roberts G, Sayre PH, Bahnson HT, Radulovic S, Santos AF, Brough HA, Phippard D, Basting M, Feeney M, Turcanu V, Sever ML, Gomez Lorenzo M, Plaut M, Lack G; LEAP Study Team (2015). Randomized trial of peanut consumption in infants at risk for peanut allergy. N Engl J Med, 372 (9), 803-813.
