Publications

EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update)

(

2021

).‎ 

Pediatr Allergy Immunol

, ‎

32

 (‎

5

)‎

843-858

https://doi.org/10.1111/pai.13496

PMID: 

33710678

PMCID: 

Halken S, Muraro A, de Silva D, Khaleva E, Angier E, Arasi S, Arshad H, Bahnson HT, Beyer K, Boyle R, du Toit G, Ebisawa M, Eigenmann P, Grimshaw K, Hoest A, Jones C, Lack G, Nadeau K, O'Mahony L, Szajewska H, Venter C, Verhasselt V, Wong GWK, Roberts G, European Academy of Allergy and Clinical Immunology Food Allergy and Anaphylaxis Guidelines Group

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

Evolution of epitope-specific IgE and IgG(4) antibodies in children enrolled in the LEAP trial

(

2021

).‎ 

J Allergy Clin Immunol

, ‎

148

 (‎

3

)‎

835-842

https://doi.org/10.1016/j.jaci.2021.01.030

PMID: 

33592205

PMCID: 

PMC8480440

Suarez-Farinas M, Suprun M, Bahnson HT, Raghunathan R, Getts R, duToit G, Lack G, Sampson HA

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy

(

2021

).‎ 

J Allergy Clin Immunol

, ‎

148

 (‎

4

)‎

1061-1071.e11

https://doi.org/10.1016/j.jaci.2021.03.030

PMID: 

33819508

PMCID: 

Shamji MH, Larson D, Eifan A, Scadding GW, Qin T, Lawson K, Sever ML, Macfarlane E, Layhadi JA, Würtzen PA, Parkin RV, Sanda S, Harris KM, Nepom GT, Togias A, Durham SR

Associated Clinical Trial(s): 

ITN043AD

 

GRASS

Stem, Effector, and Hybrid States of Memory CD8(+) T Cells

(

2020

).‎ 

Trends Immunol

, ‎

41

 (‎

1

)‎

17-28

https://doi.org/10.1016/j.it.2019.11.004

PMID: 

31810790

PMCID: 

PMC6934921

Lugli E, Galletti G, Boi SK, Youngblood BA

Associated Clinical Trial(s): 

Beta cell-specific CD8(+) T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes

(

2020

).‎ 

Nat Immunol

, ‎

21

 (‎

5

)‎

578-587

https://doi.org/10.1038/s41590-020-0633-5

PMID: 

32231298

PMCID: 

PMC7183435

Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B

Associated Clinical Trial(s): 

Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression

(

2020

).‎ 

J Clin Invest

, ‎

130

 (‎

1

)‎

480-490

https://doi.org/10.1172/JCI126595

PMID: 

31815738

PMCID: 

PMC6934185

Wiedeman AE, Muir VS, Rosasco MG, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James EA, Linsley PS, Long SA

Associated Clinical Trial(s): 

IgG4 donor-specific HLA antibody profile is associated with subclinical rejection in stable pediatric liver recipients

(

2020

).‎ 

Am J Transplant

, ‎

20

 (‎

2

)‎

513-524

https://doi.org/10.1111/ajt.15621

PMID: 

31561279

PMCID: 

Jackson AM, Kanaparthi S, Burrell BE, Lucas DP, Vega RM, Demetris AJ, Feng S

Associated Clinical Trial(s): 

Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus

(

2020

).‎ 

Hepatology

, ‎

72

 (‎

2

)‎

569-583

https://doi.org/10.1002/hep.31036

PMID: 

31721246

PMCID: 

PMC7217743

Levitsky J, Burrell BE, Kanaparthi S, Turka LA, Kurian S, Sanchez-Fueyo A, Lozano JJ, Demetris A, Lesniak A, Kirk AD, Stempora L, Yang GY, Mathew JM

Associated Clinical Trial(s): 

Deletion of donor-reactive T cell clones after human liver transplant

(

2020

).‎ 

Am J Transplant

, ‎

20

 (‎

2

)‎

538-545

https://doi.org/10.1111/ajt.15592

PMID: 

31509321

PMCID: 

PMC6984984

Savage TM, Shonts BA, Lau S, Obradovic A, Robins H, Shaked A, Shen Y, Sykes M

Associated Clinical Trial(s): 

ITN030ST

 

A-WISH

Biomarkers of severity and threshold of allergic reactions during oral peanut challenges

(

2020

).‎ 

J Allergy Clin Immunol

, ‎

146

 (‎

2

)‎

344-355

https://doi.org/10.1016/j.jaci.2020.03.035

PMID: 

32311390

PMCID: 

PMC7417812

Santos AF, Du Toit G, O'Rourke C, Becares N, Couto-Francisco N, Radulovic S, Khaleva E, Basting M, Harris KM, Larson D, Sayre P, Plaut M, Roberts G, Bahnson HT, Lack G

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

Precision transplant pathology

(

2020

).‎ 

Curr Opin Organ Transplant

, ‎

25

 (‎

4

)‎

412-419

https://doi.org/10.1097/MOT.0000000000000772

PMID: 

32520786

PMCID: 

PMC7737245

Wood-Trageser MA, Xu Q, Zeevi A, Randhawa P, Lesniak D, Demetris AJ

Associated Clinical Trial(s): 

Fc receptor-like 5 and anti-CD20 treatment response in granulomatosis with polyangiitis and microscopic polyangiitis

(

2020

).‎ 

JCI Insight

, ‎

5

 (‎

18

)‎

e136180

https://doi.org/10.1172/jci.insight.136180

PMID: 

32841219

PMCID: 

PMC7526555

Owczarczyk K, Cascino MD, Holweg C, Tew GW, Ortmann W, Behrens T, Schindler T, Langford CA, St Clair EW, Merkel PA, Spiera R, Seo P, Kallenberg CG, Specks U, Lim N, Stone J, Brunetta P, Prunotto M, RAVE-ITN Research Group

Associated Clinical Trial(s): 

ITN021AI

 

RAVE

Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3 in ANCA-Associated Vasculitis

(

2020

).‎ 

Front Immunol

, ‎

11

 (‎

)‎

2053

https://doi.org/10.3389/fimmu.2020.02053

PMID: 

33013868

PMCID: 

PMC7495134

Thompson GE, Fussner LA, Hummel AM, Schroeder DR, Silva F, Snyder MR, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Stone JH, Specks U

Associated Clinical Trial(s): 

ITN021AI

 

RAVE

Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis

(

2020

).‎ 

JCI Insight

, ‎

5

 (‎

2

)‎

e127655

https://doi.org/10.1172/jci.insight.127655

PMID: 

31877116

PMCID: 

PMC7098711

Harris KM, Lim N, Lindau P, Robins H, Griffith LM, Nash RA, Turka LA, Muraro PA

Associated Clinical Trial(s): 

ITN033AI

 

HALT MS

Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited

(

2020

).‎ 

Clin Pharmacokinet

, ‎

59

 (‎

4

)‎

519-530

https://doi.org/10.1007/s40262-019-00826-5

PMID: 

31586310

PMCID: 

Bensalem A, Mulleman D, Paintaud G, Azzopardi N, Gouilleux-Gruart V, Cornec D, Specks U, Ternant D

Associated Clinical Trial(s): 

ITN021AI

 

RAVE

IgE to epitopes of Ara h 2 enhance the diagnostic accuracy of Ara h 2-specific IgE

(

2020

).‎ 

Allergy

, ‎

75

 (‎

9

)‎

2309-2318

https://doi.org/10.1111/all.14301

PMID: 

32248566

PMCID: 

Santos AF, Barbosa-Morais NL, Hurlburt BK, Ramaswamy S, Hemmings O, Kwok M, O'Rourke C, Bahnson HT, Cheng H, James L, Gould HJ, Sutton BJ, Maleki SJ, Lack G

Associated Clinical Trial(s): 

Epicutaneous sensitization in the development of food allergy: What is the evidence and how can this be prevented?

(

2020

).‎ 

Allergy

, ‎

75

 (‎

9

)‎

2185-2205

https://doi.org/10.1111/all.14304

PMID: 

32249942

PMCID: 

PMC7494573

Brough HA, Nadeau KC, Sindher SB, Alkotob SS, Chan S, Bahnson HT, Leung DYM, Lack G

Associated Clinical Trial(s): 

Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance

(

2020

).‎ 

Annu Rev Cell Dev Biol

, ‎

36

 (‎

)‎

511-528

https://doi.org/10.1146/annurev-cellbio-100818-125346

PMID: 

32634325

PMCID: 

Logan K, Du Toit G, Giovannini M, Turcanu V, Lack G

Associated Clinical Trial(s): 

Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2

(

2020

).‎ 

J Allergy Clin Immunol

, ‎

146

 (‎

1

)‎

203-206.e3

https://doi.org/10.1016/j.jaci.2020.04.009

PMID: 

32333915

PMCID: 

PMC7175851

Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC

Associated Clinical Trial(s): 

ITN061AD

 

Cat EEC

Nasal allergen challenge and environmental exposure chamber challenge: A randomized trial comparing clinical and biological responses to cat allergen

(

2020

).‎ 

J Allergy Clin Immunol

, ‎

145

 (‎

6

)‎

1585-1597

https://doi.org/10.1016/j.jaci.2020.02.024

PMID: 

32169380

PMCID: 

PMC8958045

Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James EA, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR

Associated Clinical Trial(s): 

ITN061AD

 

Cat EEC

Prevalence and Impact of De Novo Donor-Specific Antibodies During a Multicenter Immunosuppression Withdrawal Trial in Adult Liver Transplant Recipients

(

2019

).‎ 

Hepatology

, ‎

69

 (‎

3

)‎

1273-1286

https://doi.org/10.1002/hep.30281

PMID: 

30229989

PMCID: 

Jucaud V, Shaked A, DesMarais M, Sayre P, Feng S, Levitsky J, Everly MJ

Associated Clinical Trial(s): 

Establishing Surrogate Kidney End Points for Lupus Nephritis Clinical Trials: Development and Validation of a Novel Approach to Predict Future Kidney Outcomes

(

2019

).‎ 

Arthritis Rheumatol

, ‎

71

 (‎

3

)‎

411-419

https://doi.org/10.1002/art.40724

PMID: 

30225865

PMCID: 

Mackay M, Dall'Era M, Fishbein J, Kalunian K, Lesser M, Sanchez-Guerrero J, Levy DM, Silverman E, Petri M, Arriens C, Lewis EJ, Korbet SM, Conti F, Tesar V, Hruskova Z, Borba EF, Bonfa E, Chan TM, Rathi M, Gupta KL, Jha V, Hasni S, West MR, Solomons N, Houssiau FA, Romero-Diaz J, Mejia-Vilet J, Rovin BH

Associated Clinical Trial(s): 

Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis

(

2019

).‎ 

Diabetologia

, ‎

62

 (‎

4

)‎

655-664

https://doi.org/10.1007/s00125-018-4786-9

PMID: 

30569273

PMCID: 

PMC6402971

Perdigoto AL, Preston-Hurlburt P, Clark P, Long SA, Linsley PS, Harris KM, Gitelman SE, Greenbaum CJ, Gottlieb PA, Hagopian W, Woodwyk A, Dziura J, Herold KC, Immune Tolerance Network

Associated Clinical Trial(s): 

ITN027AI

 

AbATE

Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables

(

2019

).‎ 

Diabetologia

, ‎

62

 (‎

1

)‎

33-40

https://doi.org/10.1007/s00125-018-4722-z

PMID: 

30167735

PMCID: 

PMC6518395

Wentworth JM, Bediaga NG, Giles LC, Ehlers M, Gitelman SE, Geyer S, Evans-Molina C, Harrison LC, Type 1 Diabetes TrialNet Study Group, Immune Tolerance Network Study Group

Associated Clinical Trial(s): 

ITN028AI

 

START

A composite immune signature parallels disease progression across T1D subjects

(

2019

).‎ 

JCI Insight

, ‎

4

 (‎

23

)‎

126917

https://doi.org/10.1172/jci.insight.126917

PMID: 

31671072

PMCID: 

PMC6962023

Speake C, Skinner SO, Berel D, Whalen E, Dufort MJ, Young WC, Odegard JM, Pesenacker AM, Gorus FK, James EA, Levings MK, Linsley PS, Akirav EM, Pugliese A, Hessner MJ, Nepom GT, Gottardo R, Long SA

Associated Clinical Trial(s): 

ITN045AI

 

T1DAL

Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study

(

2019

).‎ 

Front Immunol

, ‎

10

 (‎

)‎

2023

https://doi.org/10.3389/fimmu.2019.02023

PMID: 

31572352

PMCID: 

PMC6753618

Speake C, Bahnson HT, Wesley JD, Perdue N, Friedrich D, Pham MN, Lanxon-Cookson E, Kwok WW, Sehested Hansen B, von Herrath M, Greenbaum CJ

Associated Clinical Trial(s): 

ITN045AI

 

T1DAL

Elicited and pre-existing anti-Neu5Gc antibodies differentially affect human endothelial cells transcriptome

(

2019

).‎ 

Xenotransplantation

, ‎

26

 (‎

6

)‎

e12535

https://doi.org/10.1111/xen.12535

PMID: 

31293002

PMCID: 

Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Arye S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP

Associated Clinical Trial(s): 

ITN028AI

 

START

Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes

(

2019

).‎ 

Genes Immun

, ‎

20

 (‎

4

)‎

293-307

https://doi.org/10.1038/s41435-018-0032-1

PMID: 

29925930

PMCID: 

PMC6477779

Linsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ

Associated Clinical Trial(s): 

ITN027AI

 

AbATE

Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA(1c), and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data

(

2019

).‎ 

Diabetes

, ‎

68

 (‎

6

)‎

1267-1276

https://doi.org/10.2337/db19-0057

PMID: 

30967424

PMCID: 

PMC6610026

Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer JP, Bundy BN, Geyer SM, Warnock MV, Miller JL, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell WE, Wilson DM, Greenbaum CJ, Type 1 Diabetes TrialNet ATG-GCSF Study Group

Associated Clinical Trial(s): 

Treg gene signatures predict and measure type 1 diabetes trajectory

(

2019

).‎ 

JCI Insight

, ‎

4

 (‎

6

)‎

e123879

https://doi.org/10.1172/jci.insight.123879

PMID: 

30730852

PMCID: 

PMC6483004

Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK

Associated Clinical Trial(s): 

ITN045AI

 

T1DAL

ITN028AI

 

START

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