EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update)
Halken S, Muraro A, de Silva D, Khaleva E, Angier E, Arasi S, Arshad H, Bahnson HT, Beyer K, Boyle R, du Toit G, Ebisawa M, Eigenmann P, Grimshaw K, Hoest A, Jones C, Lack G, Nadeau K, O'Mahony L, Szajewska H, Venter C, Verhasselt V, Wong GWK, Roberts G, European Academy of Allergy and Clinical Immunology Food Allergy and Anaphylaxis Guidelines Group
Associated Clinical Trial(s):
Halken S, Muraro A, de Silva D, Khaleva E, Angier E, Arasi S, Arshad H, Bahnson HT, Beyer K, Boyle R, du Toit G, Ebisawa M, Eigenmann P, Grimshaw K, Hoest A, Jones C, Lack G, Nadeau K, O'Mahony L, Szajewska H, Venter C, Verhasselt V, Wong GWK, Roberts G, European Academy of Allergy and Clinical Immunology Food Allergy and Anaphylaxis Guidelines Group (2021). EAACI guideline: Preventing the development of food allergy in infants and young children (2020 update). Pediatr Allergy Immunol, 32(5), 843-858. https://doi.org/10.1111/pai.13496 PMID: 33710678.
Evolution of epitope-specific IgE and IgG(4) antibodies in children enrolled in the LEAP trial
Suarez-Farinas M, Suprun M, Bahnson HT, Raghunathan R, Getts R, duToit G, Lack G, Sampson HA
Associated Clinical Trial(s):
Suarez-Farinas M, Suprun M, Bahnson HT, Raghunathan R, Getts R, duToit G, Lack G, Sampson HA (2021). Evolution of epitope-specific IgE and IgG(4) antibodies in children enrolled in the LEAP trial. J Allergy Clin Immunol, 148(3), 835-842. https://doi.org/10.1016/j.jaci.2021.01.030 PMID: 33592205. PMCID: PMC8480440.
Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy
Shamji MH, Larson D, Eifan A, Scadding GW, Qin T, Lawson K, Sever ML, Macfarlane E, Layhadi JA, Würtzen PA, Parkin RV, Sanda S, Harris KM, Nepom GT, Togias A, Durham SR
Associated Clinical Trial(s):
Shamji MH, Larson D, Eifan A, Scadding GW, Qin T, Lawson K, Sever ML, Macfarlane E, Layhadi JA, Würtzen PA, Parkin RV, Sanda S, Harris KM, Nepom GT, Togias A, Durham SR (2021). Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy. J Allergy Clin Immunol, 148(4), 1061-1071.e11. https://doi.org/10.1016/j.jaci.2021.03.030 PMID: 33819508.
Stem, Effector, and Hybrid States of Memory CD8(+) T Cells
Lugli E, Galletti G, Boi SK, Youngblood BA
Associated Clinical Trial(s):
Lugli E, Galletti G, Boi SK, Youngblood BA (2020). Stem, Effector, and Hybrid States of Memory CD8(+) T Cells. Trends Immunol, 41(1), 17-28. https://doi.org/10.1016/j.it.2019.11.004 PMID: 31810790. PMCID: PMC6934921.
Beta cell-specific CD8(+) T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B
Associated Clinical Trial(s):
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B (2020). Beta cell-specific CD8(+) T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nat Immunol, 21(5), 578-587. https://doi.org/10.1038/s41590-020-0633-5 PMID: 32231298. PMCID: PMC7183435.
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression
Wiedeman AE, Muir VS, Rosasco MG, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James EA, Linsley PS, Long SA
Associated Clinical Trial(s):
Wiedeman AE, Muir VS, Rosasco MG, DeBerg HA, Presnell S, Haas B, Dufort MJ, Speake C, Greenbaum CJ, Serti E, Nepom GT, Blahnik G, Kus AM, James EA, Linsley PS, Long SA (2020). Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression. J Clin Invest, 130(1), 480-490. https://doi.org/10.1172/JCI126595 PMID: 31815738. PMCID: PMC6934185.
IgG4 donor-specific HLA antibody profile is associated with subclinical rejection in stable pediatric liver recipients
Jackson AM, Kanaparthi S, Burrell BE, Lucas DP, Vega RM, Demetris AJ, Feng S
Associated Clinical Trial(s):
Jackson AM, Kanaparthi S, Burrell BE, Lucas DP, Vega RM, Demetris AJ, Feng S (2020). IgG4 donor-specific HLA antibody profile is associated with subclinical rejection in stable pediatric liver recipients. Am J Transplant, 20(2), 513-524. https://doi.org/10.1111/ajt.15621 PMID: 31561279.
Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus
Levitsky J, Burrell BE, Kanaparthi S, Turka LA, Kurian S, Sanchez-Fueyo A, Lozano JJ, Demetris A, Lesniak A, Kirk AD, Stempora L, Yang GY, Mathew JM
Associated Clinical Trial(s):
Levitsky J, Burrell BE, Kanaparthi S, Turka LA, Kurian S, Sanchez-Fueyo A, Lozano JJ, Demetris A, Lesniak A, Kirk AD, Stempora L, Yang GY, Mathew JM (2020). Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus. Hepatology, 72(2), 569-583. https://doi.org/10.1002/hep.31036 PMID: 31721246. PMCID: PMC7217743.
Deletion of donor-reactive T cell clones after human liver transplant
Savage TM, Shonts BA, Lau S, Obradovic A, Robins H, Shaked A, Shen Y, Sykes M
Associated Clinical Trial(s):
Savage TM, Shonts BA, Lau S, Obradovic A, Robins H, Shaked A, Shen Y, Sykes M (2020). Deletion of donor-reactive T cell clones after human liver transplant. Am J Transplant, 20(2), 538-545. https://doi.org/10.1111/ajt.15592 PMID: 31509321. PMCID: PMC6984984.
Biomarkers of severity and threshold of allergic reactions during oral peanut challenges
Santos AF, Du Toit G, O'Rourke C, Becares N, Couto-Francisco N, Radulovic S, Khaleva E, Basting M, Harris KM, Larson D, Sayre P, Plaut M, Roberts G, Bahnson HT, Lack G
Associated Clinical Trial(s):
Santos AF, Du Toit G, O'Rourke C, Becares N, Couto-Francisco N, Radulovic S, Khaleva E, Basting M, Harris KM, Larson D, Sayre P, Plaut M, Roberts G, Bahnson HT, Lack G (2020). Biomarkers of severity and threshold of allergic reactions during oral peanut challenges. J Allergy Clin Immunol, 146(2), 344-355. https://doi.org/10.1016/j.jaci.2020.03.035 PMID: 32311390. PMCID: PMC7417812.
Precision transplant pathology
Wood-Trageser MA, Xu Q, Zeevi A, Randhawa P, Lesniak D, Demetris AJ
Associated Clinical Trial(s):
Wood-Trageser MA, Xu Q, Zeevi A, Randhawa P, Lesniak D, Demetris AJ (2020). Precision transplant pathology. Curr Opin Organ Transplant, 25(4), 412-419. https://doi.org/10.1097/MOT.0000000000000772 PMID: 32520786. PMCID: PMC7737245.
Fc receptor-like 5 and anti-CD20 treatment response in granulomatosis with polyangiitis and microscopic polyangiitis
Owczarczyk K, Cascino MD, Holweg C, Tew GW, Ortmann W, Behrens T, Schindler T, Langford CA, St Clair EW, Merkel PA, Spiera R, Seo P, Kallenberg CG, Specks U, Lim N, Stone J, Brunetta P, Prunotto M, RAVE-ITN Research Group
Associated Clinical Trial(s):
Owczarczyk K, Cascino MD, Holweg C, Tew GW, Ortmann W, Behrens T, Schindler T, Langford CA, St Clair EW, Merkel PA, Spiera R, Seo P, Kallenberg CG, Specks U, Lim N, Stone J, Brunetta P, Prunotto M, RAVE-ITN Research Group (2020). Fc receptor-like 5 and anti-CD20 treatment response in granulomatosis with polyangiitis and microscopic polyangiitis. JCI Insight, 5(18). https://doi.org/10.1172/jci.insight.136180 PMID: 32841219. PMCID: PMC7526555.
Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3 in ANCA-Associated Vasculitis
Thompson GE, Fussner LA, Hummel AM, Schroeder DR, Silva F, Snyder MR, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Stone JH, Specks U
Associated Clinical Trial(s):
Thompson GE, Fussner LA, Hummel AM, Schroeder DR, Silva F, Snyder MR, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Stone JH, Specks U (2020). Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3 in ANCA-Associated Vasculitis. Front Immunol, 11, 2053. https://doi.org/10.3389/fimmu.2020.02053 PMID: 33013868. PMCID: PMC7495134.
Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis
Harris KM, Lim N, Lindau P, Robins H, Griffith LM, Nash RA, Turka LA, Muraro PA
Associated Clinical Trial(s):
Harris KM, Lim N, Lindau P, Robins H, Griffith LM, Nash RA, Turka LA, Muraro PA (2020). Extensive intrathecal T cell renewal following hematopoietic transplantation for multiple sclerosis. JCI Insight, 5(2). https://doi.org/10.1172/jci.insight.127655 PMID: 31877116. PMCID: PMC7098711.
Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited
Bensalem A, Mulleman D, Paintaud G, Azzopardi N, Gouilleux-Gruart V, Cornec D, Specks U, Ternant D
Associated Clinical Trial(s):
Bensalem A, Mulleman D, Paintaud G, Azzopardi N, Gouilleux-Gruart V, Cornec D, Specks U, Ternant D (2020). Non-Linear Rituximab Pharmacokinetics and Complex Relationship between Rituximab Concentrations and Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in ANCA-Associated Vasculitis: The RAVE Trial Revisited. Clin Pharmacokinet, 59(4), 519-530. https://doi.org/10.1007/s40262-019-00826-5 PMID: 31586310.
IgE to epitopes of Ara h 2 enhance the diagnostic accuracy of Ara h 2-specific IgE
Santos AF, Barbosa-Morais NL, Hurlburt BK, Ramaswamy S, Hemmings O, Kwok M, O'Rourke C, Bahnson HT, Cheng H, James L, Gould HJ, Sutton BJ, Maleki SJ, Lack G
Associated Clinical Trial(s):
Santos AF, Barbosa-Morais NL, Hurlburt BK, Ramaswamy S, Hemmings O, Kwok M, O'Rourke C, Bahnson HT, Cheng H, James L, Gould HJ, Sutton BJ, Maleki SJ, Lack G (2020). IgE to epitopes of Ara h 2 enhance the diagnostic accuracy of Ara h 2-specific IgE. Allergy, 75(9), 2309-2318. https://doi.org/10.1111/all.14301 PMID: 32248566.
Epicutaneous sensitization in the development of food allergy: What is the evidence and how can this be prevented?
Brough HA, Nadeau KC, Sindher SB, Alkotob SS, Chan S, Bahnson HT, Leung DYM, Lack G
Associated Clinical Trial(s):
Brough HA, Nadeau KC, Sindher SB, Alkotob SS, Chan S, Bahnson HT, Leung DYM, Lack G (2020). Epicutaneous sensitization in the development of food allergy: What is the evidence and how can this be prevented? Allergy, 75(9), 2185-2205. https://doi.org/10.1111/all.14304 PMID: 32249942. PMCID: PMC7494573.
Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance
Logan K, Du Toit G, Giovannini M, Turcanu V, Lack G
Associated Clinical Trial(s):
Logan K, Du Toit G, Giovannini M, Turcanu V, Lack G (2020). Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance. Annu Rev Cell Dev Biol, 36, 511-528. https://doi.org/10.1146/annurev-cellbio-100818-125346 PMID: 32634325.
Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2
Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC
Associated Clinical Trial(s):
Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, Ober C, Gergen PJ, Becker P, Togias A, Gern JE, Altman MC (2020). Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2. J Allergy Clin Immunol, 146(1), 203-206.e3. https://doi.org/10.1016/j.jaci.2020.04.009 PMID: 32333915. PMCID: PMC7175851.
Nasal allergen challenge and environmental exposure chamber challenge: A randomized trial comparing clinical and biological responses to cat allergen
Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James EA, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR
Associated Clinical Trial(s):
Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James EA, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR (2020). Nasal allergen challenge and environmental exposure chamber challenge: A randomized trial comparing clinical and biological responses to cat allergen. J Allergy Clin Immunol, 145(6), 1585-1597. https://doi.org/10.1016/j.jaci.2020.02.024 PMID: 32169380. PMCID: PMC8958045.
Prevalence and Impact of De Novo Donor-Specific Antibodies During a Multicenter Immunosuppression Withdrawal Trial in Adult Liver Transplant Recipients
Jucaud V, Shaked A, DesMarais M, Sayre P, Feng S, Levitsky J, Everly MJ
Associated Clinical Trial(s):
Jucaud V, Shaked A, DesMarais M, Sayre P, Feng S, Levitsky J, Everly MJ (2019). Prevalence and Impact of De Novo Donor-Specific Antibodies During a Multicenter Immunosuppression Withdrawal Trial in Adult Liver Transplant Recipients. Hepatology, 69(3), 1273-1286. https://doi.org/10.1002/hep.30281 PMID: 30229989.
Establishing Surrogate Kidney End Points for Lupus Nephritis Clinical Trials: Development and Validation of a Novel Approach to Predict Future Kidney Outcomes
Mackay M, Dall'Era M, Fishbein J, Kalunian K, Lesser M, Sanchez-Guerrero J, Levy DM, Silverman E, Petri M, Arriens C, Lewis EJ, Korbet SM, Conti F, Tesar V, Hruskova Z, Borba EF, Bonfa E, Chan TM, Rathi M, Gupta KL, Jha V, Hasni S, West MR, Solomons N, Houssiau FA, Romero-Diaz J, Mejia-Vilet J, Rovin BH
Associated Clinical Trial(s):
Mackay M, Dall'Era M, Fishbein J, Kalunian K, Lesser M, Sanchez-Guerrero J, Levy DM, Silverman E, Petri M, Arriens C, Lewis EJ, Korbet SM, Conti F, Tesar V, Hruskova Z, Borba EF, Bonfa E, Chan TM, Rathi M, Gupta KL, Jha V, Hasni S, West MR, Solomons N, Houssiau FA, Romero-Diaz J, Mejia-Vilet J, Rovin BH (2019). Establishing Surrogate Kidney End Points for Lupus Nephritis Clinical Trials: Development and Validation of a Novel Approach to Predict Future Kidney Outcomes. Arthritis Rheumatol, 71(3), 411-419. https://doi.org/10.1002/art.40724 PMID: 30225865.
Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis
Perdigoto AL, Preston-Hurlburt P, Clark P, Long SA, Linsley PS, Harris KM, Gitelman SE, Greenbaum CJ, Gottlieb PA, Hagopian W, Woodwyk A, Dziura J, Herold KC, Immune Tolerance Network
Associated Clinical Trial(s):
Perdigoto AL, Preston-Hurlburt P, Clark P, Long SA, Linsley PS, Harris KM, Gitelman SE, Greenbaum CJ, Gottlieb PA, Hagopian W, Woodwyk A, Dziura J, Herold KC, Immune Tolerance Network (2019). Treatment of type 1 diabetes with teplizumab: clinical and immunological follow-up after 7 years from diagnosis. Diabetologia, 62(4), 655-664. https://doi.org/10.1007/s00125-018-4786-9 PMID: 30569273. PMCID: PMC6402971.
Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables
Wentworth JM, Bediaga NG, Giles LC, Ehlers M, Gitelman SE, Geyer S, Evans-Molina C, Harrison LC, Type 1 Diabetes TrialNet Study Group, Immune Tolerance Network Study Group
Associated Clinical Trial(s):
Wentworth JM, Bediaga NG, Giles LC, Ehlers M, Gitelman SE, Geyer S, Evans-Molina C, Harrison LC, Type 1 Diabetes TrialNet Study Group, Immune Tolerance Network Study Group (2019). Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables. Diabetologia, 62(1), 33-40. https://doi.org/10.1007/s00125-018-4722-z PMID: 30167735. PMCID: PMC6518395.
A composite immune signature parallels disease progression across T1D subjects
Speake C, Skinner SO, Berel D, Whalen E, Dufort MJ, Young WC, Odegard JM, Pesenacker AM, Gorus FK, James EA, Levings MK, Linsley PS, Akirav EM, Pugliese A, Hessner MJ, Nepom GT, Gottardo R, Long SA
Associated Clinical Trial(s):
Speake C, Skinner SO, Berel D, Whalen E, Dufort MJ, Young WC, Odegard JM, Pesenacker AM, Gorus FK, James EA, Levings MK, Linsley PS, Akirav EM, Pugliese A, Hessner MJ, Nepom GT, Gottardo R, Long SA (2019). A composite immune signature parallels disease progression across T1D subjects. JCI Insight, 4(23). https://doi.org/10.1172/jci.insight.126917 PMID: 31671072. PMCID: PMC6962023.
Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study
Speake C, Bahnson HT, Wesley JD, Perdue N, Friedrich D, Pham MN, Lanxon-Cookson E, Kwok WW, Sehested Hansen B, von Herrath M, Greenbaum CJ
Associated Clinical Trial(s):
Speake C, Bahnson HT, Wesley JD, Perdue N, Friedrich D, Pham MN, Lanxon-Cookson E, Kwok WW, Sehested Hansen B, von Herrath M, Greenbaum CJ (2019). Systematic Assessment of Immune Marker Variation in Type 1 Diabetes: A Prospective Longitudinal Study. Front Immunol, 10, 2023. https://doi.org/10.3389/fimmu.2019.02023 PMID: 31572352. PMCID: PMC6753618.
Elicited and pre-existing anti-Neu5Gc antibodies differentially affect human endothelial cells transcriptome
Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Arye S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP
Associated Clinical Trial(s):
Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Arye S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP (2019). Elicited and pre-existing anti-Neu5Gc antibodies differentially affect human endothelial cells transcriptome. Xenotransplantation, 26(6), e12535. https://doi.org/10.1111/xen.12535 PMID: 31293002.
Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes
Linsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ
Associated Clinical Trial(s):
Linsley PS, Greenbaum CJ, Rosasco M, Presnell S, Herold KC, Dufort MJ (2019). Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes. Genes Immun, 20(4), 293-307. https://doi.org/10.1038/s41435-018-0032-1 PMID: 29925930. PMCID: PMC6477779.
Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA(1c), and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data
Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer JP, Bundy BN, Geyer SM, Warnock MV, Miller JL, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell WE, Wilson DM, Greenbaum CJ, Type 1 Diabetes TrialNet ATG-GCSF Study Group
Associated Clinical Trial(s):
Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer JP, Bundy BN, Geyer SM, Warnock MV, Miller JL, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell WE, Wilson DM, Greenbaum CJ, Type 1 Diabetes TrialNet ATG-GCSF Study Group (2019). Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA(1c), and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data. Diabetes, 68(6), 1267-1276. https://doi.org/10.2337/db19-0057 PMID: 30967424. PMCID: PMC6610026.
Treg gene signatures predict and measure type 1 diabetes trajectory
Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK
Associated Clinical Trial(s):
Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK (2019). Treg gene signatures predict and measure type 1 diabetes trajectory. JCI Insight, 4(6). https://doi.org/10.1172/jci.insight.123879 PMID: 30730852. PMCID: PMC6483004.