Publications

Letter of response to Greenhawt et al. 'LEAPing Through the Looking Glass: Secondary Analysis of the Effect of Skin Test Size and Age of Introduction on Peanut Tolerance after Early Peanut Introduction'

(

2017

).‎ 

Allergy

, ‎

72

 (‎

8

)‎

1267-1271

https://doi.org/10.1111/all.13127

PMID: 

28691223

PMCID: 

PMC5796413

Lawson K, Bahnson HT, Brittain E, Sever M, Du Toit G, Lack G, Keet C, Greenhawt M, Fleischer D, Chan ES, Venter C, Stukus D, Gupta R, Spergel J

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

Statistical Considerations of Food Allergy Prevention Studies

(

2017

).‎ 

J Allergy Clin Immunol Pract

, ‎

5

 (‎

2

)‎

274-282

https://doi.org/10.1016/j.jaip.2016.12.007

PMID: 

28283152

PMCID: 

PMC5683073

Bahnson HT, du Toit G, Lack G

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

Food Allergy: Unmet Needs and New Perspectives

(

2017

).‎ 

J Allergy Clin Immunol Pract

, ‎

5

 (‎

2

)‎

295

https://doi.org/10.1016/j.jaip.2017.01.002

PMID: 

28283155

PMCID: 

Wang J, Lack G

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

LEAPing through the looking glass: secondary analysis of the effect of skin test size and age of introduction on peanut tolerance after early peanut introduction

(

2017

).‎ 

Allergy

, ‎

72

 (‎

8

)‎

1254-1260

https://doi.org/10.1111/all.13100

PMID: 

27896827

PMCID: 

PMC5447487

Greenhawt M, Fleischer DM, Chan ES, Venter C, Stukus D, Gupta R, Spergel JM

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

Effect of 2 Years of Treatment With Sublingual Grass Pollen Immunotherapy on Nasal Response to Allergen Challenge at 3 Years Among Patients With Moderate to Severe Seasonal Allergic Rhinitis: The GRASS Randomized Clinical Trial

(

2017

).‎ 

JAMA

, ‎

317

 (‎

6

)‎

615-625

https://doi.org/10.1001/jama.2016.21040

PMID: 

28196255

PMCID: 

PMC5479315

Scadding GW, Calderon MA, Shamji MH, Eifan AO, Penagos M, Dumitru F, Sever ML, Bahnson HT, Lawson K, Harris KM, Plough AG, Panza JL, Qin T, Lim N, Tchao NK, Togias A, Durham SR, Immune Tolerance Network GRASS Study Team

Associated Clinical Trial(s): 

ITN043AD

 

GRASS

Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants

(

2016

).‎ 

N Engl J Med

, ‎

374

 (‎

18

)‎

1733-43

https://doi.org/10.1056/NEJMoa1514210

PMID: 

26943128

PMCID: 

Perkin MR, Logan K, Tseng A, Raji B, Ayis S, Peacock J, Brough H, Marrs T, Radulovic S, Craven J, Flohr C, Lack G, EAT Study Team

Associated Clinical Trial(s): 

Features of patients screened for calibrate (rituximab plus cyclophosphamide followed by belimumab for the treatment of lupus nephritis); hypogammaglobulinemia is frequent in patients with marked elevation of urinary protein

(

2016

).‎ 

Lupus Sci Med

, ‎

 (‎

31 August 2016

)‎

https://doi.org/10.1136/lupus-2016-000179.74

PMID: 

PMCID: 

Associated Clinical Trial(s): 

International Consensus on Allergen Immunotherapy II: Mechanisms, standardization, and pharmacoeconomics

(

2016

).‎ 

J Allergy Clin Immunol

, ‎

137

 (‎

2

)‎

358-68

https://doi.org/10.1016/j.jaci.2015.12.1300

PMID: 

26853128

PMCID: 

Jutel M, Agache I, Bonini S, Burks AW, Calderon M, Canonica W, Cox L, Demoly P, Frew AJ, O'Hehir R, Kleine-Tebbe J, Muraro A, Lack G, Larenas D, Levin M, Martin BL, Nelson H, Pawankar R, Pfaar O, van Ree R, Sampson H, Sublett JL, Sugita K, Du Toit G, Werfel T, Gerth van Wijk R, Zhang L, Akdis M, Akdis CA

Associated Clinical Trial(s): 

Clinical trial data access: Opening doors with TrialShare

(

2016

).‎ 

J Allergy Clin Immunol

, ‎

138

 (‎

3

)‎

724-726

https://doi.org/10.1016/j.jaci.2016.05.034

PMID: 

27474121

PMCID: 

Asare AL, Carey VJ, Rotrosen D, Nepom GT

Associated Clinical Trial(s): 

Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes

(

2016

).‎ 

J Autoimmun

, ‎

71

 (‎

71

)‎

44-50

https://doi.org/10.1016/j.jaut.2016.02.009

PMID: 

26948997

PMCID: 

PMC4903876

Buckner JH, Nepom GT

Associated Clinical Trial(s): 

ITN045AI

 

T1DAL

ITN027AI

 

AbATE

Strategies for clinical trials in type 1 diabetes

(

2016

).‎ 

J Autoimmun

, ‎

71

 (‎

71

)‎

88-96

https://doi.org/10.1016/j.jaut.2016.03.008

PMID: 

27068279

PMCID: 

PMC4903883

Ehlers MR

Associated Clinical Trial(s): 

Immune interventions to preserve β cell function in type 1 diabetes

(

2016

).‎ 

J Investig Med

, ‎

64

 (‎

1

)‎

7-13

https://doi.org/10.1097/JIM.0000000000000227

PMID: 

26225763

PMCID: 

PMC4732932

Ehlers MR

Associated Clinical Trial(s): 

ITN045AI

 

T1DAL

ITN028AI

 

START

ITN027AI

 

AbATE

Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes

(

2016

).‎ 

Sci Immunol

, ‎

1

 (‎

5

)‎

pii: eaai7793

https://doi.org/10.1126/sciimmunol.aai7793

PMID: 

28664195

PMCID: 

PMC5486405

Long SA, Thorpe J, DeBerg HA, Gersuk V, Eddy J, Harris KM, Ehlers M, Herold KC, Nepom GT, Linsley PS

Associated Clinical Trial(s): 

ITN027AI

 

AbATE

Correlation Among Hypoglycemia, Glycemic Variability, and C-Peptide Preservation After Alefacept Therapy in Patients with Type 1 Diabetes Mellitus: Analysis of Data from the Immune Tolerance Network T1DAL Trial

(

2016

).‎ 

Clin Ther

, ‎

38

 (‎

6

)‎

1327-1339

https://doi.org/10.1016/j.clinthera.2016.04.032

PMID: 

27209482

PMCID: 

PMC4916002

Pinckney A, Rigby MR, Keyes-Elstein L, Soppe CL, Nepom GT, Ehlers MR

Associated Clinical Trial(s): 

ITN045AI

 

T1DAL

Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2 year results of a randomised trial

(

2016

).‎ 

Diabetologia

, ‎

59

 (‎

6

)‎

1153-61

https://doi.org/10.1007/s00125-016-3917-4

PMID: 

27053235

PMCID: 

PMC4869699

Gitelman SE, Gottlieb PA, Felner EI, Willi SM, Fisher LK, Moran A, Gottschalk M, Moore WV, Pinckney A, Keyes-Elstein L, Harris KM, Kanaparthi S, Phippard D, Ding L, Bluestone JA, Ehlers MR, ITN START Study Team

Associated Clinical Trial(s): 

ITN028AI

 

START

Two- and Four-Hour Tests Differ in Capture of C-Peptide Responses to a Mixed Meal in Type 1 Diabetes

(

2016

).‎ 

Diabetes Care

, ‎

39

 (‎

6

)‎

e76-8

https://doi.org/10.2337/dc15-2077

PMID: 

27208317

PMCID: 

PMC4878222

Boyle KD, Keyes-Elstein L, Ehlers MR, McNamara J, Rigby MR, Gitelman SE, Weiner LJ, Much KL, Herold KC

Associated Clinical Trial(s): 

ITN045AI

 

T1DAL

ITN028AI

 

START

ITN027AI

 

AbATE

A Preclinical Consortium Approach for Assessing the Efficacy of Combined Anti-CD3 Plus IL-1 Blockade in Reversing New-Onset Autoimmune Diabetes in NOD Mice

(

2016

).‎ 

Diabetes

, ‎

65

 (‎

5

)‎

1310-6

https://doi.org/10.2337/db15-0492

PMID: 

26718498

PMCID: 

PMC5860426

Gill RG, Pagni PP, Kupfer T, Wasserfall CH, Deng S, Posgai A, Manenkova Y, Bel Hani A, Straub L, Bernstein P, Atkinson MA, Herold KC, von Herrath M, Staeva T, Ehlers MR, Nepom GT

Associated Clinical Trial(s): 

Changes in T-cell subsets identify responders to FcR-nonbinding anti-CD3 mAb (teplizumab) in patients with type 1 diabetes

(

2016

).‎ 

Eur J Immunol

, ‎

46

 (‎

1

)‎

230-41

https://doi.org/10.1002/eji.201545708

PMID: 

26518356

PMCID: 

PMC4882099

Tooley JE, Vudattu N, Choi J, Cotsapas C, Devine L, Raddassi K, Ehlers MR, McNamara JG, Harris KM, Kanaparthi S, Phippard D, Herold KC

Associated Clinical Trial(s): 

ITN027AI

 

AbATE

Long-Term Follow-Up of the Edmonton Protocol of Islet Transplantation in the United States

(

2016

).‎ 

Am J Transplant

, ‎

16

 (‎

2

)‎

509-17

https://doi.org/10.1111/ajt.13458

PMID: 

26433206

PMCID: 

Brennan DC, Kopetskie HA, Sayre PH, Alejandro R, Cagliero E, Shapiro AM, Goldstein JS, DesMarais MR, Booher S, Bianchine PJ

Associated Clinical Trial(s): 

ITN005CT

 

ITN040CT

 

EXIIST

Myeloperoxidase-Antineutrophil Cytoplasmic Antibody (ANCA)-Positive and ANCA-Negative Patients With Granulomatosis With Polyangiitis (Wegener's): Distinct Patient Subsets

(

2016

).‎ 

Arthritis Rheumatol

, ‎

68

 (‎

12

)‎

2945-2952

https://doi.org/10.1002/art.39812

PMID: 

27428559

PMCID: 

PMC5541999

Miloslavsky EM, Lu N, Unizony S, Choi HK, Merkel PA, Seo P, Spiera R, Langford CA, Hoffman GS, Kallenberg CG, St Clair EW, Tchao NK, Fervenza F, Monach PA, Specks U, Stone JH

Associated Clinical Trial(s): 

ITN021AI

 

RAVE

A role for plasma cell targeting agents in immune tolerance induction in autoimmune disease and antibody responses to therapeutic proteins

(

2016

).‎ 

Clin Immunol

, ‎

165

 (‎

4/1/2016

)‎

55-9

https://doi.org/10.1016/j.clim.2016.02.009

PMID: 

26928739

PMCID: 

Rosenberg AS, Pariser AR, Diamond B, Yao L, Turka LA, Lacana E, Kishnani PS

Associated Clinical Trial(s): 

International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials

(

2016

).‎ 

Cytotherapy

, ‎

18

 (‎

2

)‎

151-9

https://doi.org/10.1016/j.jcyt.2015.11.008

PMID: 

26724220

PMCID: 

PMC4745114

Galipeau J, Krampera M, Barrett J, Dazzi F, Deans RJ, DeBruijn J, Dominici M, Fibbe WE, Gee AP, Gimble JM, Hematti P, Koh MB, LeBlanc K, Martin I, McNiece IK, Mendicino M, Oh S, Ortiz L, Phinney DG, Planat V, Shi Y, Stroncek DF, Viswanathan S, Weiss DJ, Sensebe L

Associated Clinical Trial(s): 

Factors Determining the Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3

(

2016

).‎ 

Arthritis Rheumatol

, ‎

68

 (‎

7

)‎

1700-10

https://doi.org/10.1002/art.39637

PMID: 

26882078

PMCID: 

PMC7137903

Fussner LA, Hummel AM, Schroeder DR, Silva F, Cartin-Ceba R, Snyder MR, Hoffman GS, Kallenberg CG, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, William St Clair E, Tchao NK, Stone JH, Specks U, Rituximab in ANCA-Associated Vasculitis-Immune Tolerance Network Research Group

Associated Clinical Trial(s): 

ITN021AI

 

RAVE

Vitamin D in clinically isolated syndrome: evidence for possible neuroprotection

(

2016

).‎ 

Eur J Neurol

, ‎

23

 (‎

2

)‎

327-32

https://doi.org/10.1111/ene.12844

PMID: 

26518224

PMCID: 

Mowry EM, Pelletier D, Gao Z, Howell MD, Zamvil SS, Waubant E

Associated Clinical Trial(s): 

ITN020AI

 

STAYCIS

Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type

(

2016

).‎ 

Ann Rheum Dis

, ‎

75

 (‎

6

)‎

1166-9

https://doi.org/10.1136/annrheumdis-2015-208073

PMID: 

26621483

PMCID: 

PMC4908815

Unizony S, Villarreal M, Miloslavsky EM, Lu N, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, Kallenberg CM, St Clair EW, Ikle D, Tchao NK, Ding L, Brunetta P, Choi HK, Monach PA, Fervenza F, Stone JH, Specks U, RAVE-ITN Research Group

Associated Clinical Trial(s): 

ITN021AI

 

RAVE

Prevention of food allergy

(

2016

).‎ 

J Allergy Clin Immunol

, ‎

137

 (‎

4

)‎

998-1010

https://doi.org/10.1016/j.jaci.2016.02.005

PMID: 

27059727

PMCID: 

du Toit G, Tsakok T, Lack S, Lack G

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

Impact of peanut consumption in the LEAP Study: Feasibility, growth, and nutrition

(

2016

).‎ 

J Allergy Clin Immunol

, ‎

138

 (‎

4

)‎

1108-1118

https://doi.org/10.1016/j.jaci.2016.04.016

PMID: 

27297994

PMCID: 

PMC5056823

Feeney M, Du Toit G, Roberts G, Sayre PH, Lawson K, Bahnson HT, Sever ML, Radulovic S, Plaut M, Lack G, Immune Tolerance Network LEAP Study Team

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

Effect of Avoidance on Peanut Allergy after Early Peanut Consumption

(

2016

).‎ 

N Engl J Med

, ‎

374

 (‎

15

)‎

1435-43

https://doi.org/10.1056/NEJMoa1514209

PMID: 

26942922

PMCID: 

Du Toit G, Sayre PH, Roberts G, Sever ML, Lawson K, Bahnson HT, Brough HA, Santos AF, Harris KM, Radulovic S, Basting M, Turcanu V, Plaut M, Lack G, Immune Tolerance Network LEAP-On Study Team

Associated Clinical Trial(s): 

ITN032AD

 

LEAP

ITN049AD

 

Leap-On

HLA-haploidentical blood or marrow transplantation with high-dose, post-transplantation cyclophosphamide

(

2015

).‎ 

Bone Marrow Transplant

, ‎

50 Suppl 2

 (‎

0 2

)‎

S31-6

https://doi.org/10.1038/bmt.2015.92

PMID: 

26039204

PMCID: 

PMC4634886

Fuchs EJ

Associated Clinical Trial(s): 

Is the use of epinephrine a good marker of severity of allergic reactions during oral food challenges?

(

2015

).‎ 

J Allergy Clin Immunol Pract

, ‎

3

 (‎

3

)‎

429-30

https://doi.org/10.1016/j.jaip.2014.12.009

PMID: 

25956314

PMCID: 

Santos AF, Du Toit G, Lack G

Associated Clinical Trial(s): 

No items found.